Klacid Uno (Clarithromycin)

Clarithromycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, blocking the translocation step of peptide chain elongation. This action stops bacterial growth (bacteriostatic) and, at higher concentrations, can kill bacteria (bactericidal). The drug also concentrates in phagocytes, enhancing activity against intracellular pathogens.

The appropriate dose of Klacid Uno is determined by the prescribing healthcare professional based on the specific infection, patient age, weight, renal and hepatic function, and any concomitant medications. Dosage regimens are individualized and should follow the prescriber’s instructions.

Safety data for clarithromycin in pregnancy and lactation are limited. The product is classified as pregnancy category unknown, and use should only be considered when the potential benefit justifies any potential risk to the fetus. Breastfeeding mothers should consult their physician, as clarithromycin is excreted in breast milk.

To order Klacid Uno, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials. The sales team then provides pricing, availability, shipping details (including any cold‑chain requirements) and assists with import documentation.

Klacid Uno (clarithromycin) belongs to the macrolide class, offering a broad spectrum against many respiratory and skin pathogens. Compared with azithromycin, clarithromycin has a slightly longer half‑life and may achieve higher tissue concentrations, but it has a higher potential for CYP3A4 drug interactions. Choice depends on the infection, patient tolerance and interaction profile.

Klacid Uno tablets should be stored at ambient temperature, below 25 °C, in the original blister or container to protect from moisture and light. Keep the product out of reach of children and do not use after the expiry date printed on the packaging.

Klacid Uno is taken orally as a tablet. It can be swallowed whole with a glass of water, with or without food, unless the prescriber advises otherwise. Patients should follow the dosing schedule provided by their healthcare professional and complete the full course, even if symptoms improve early.

Serious adverse reactions to clarithromycin include hepatotoxicity (elevated liver enzymes or jaundice) and QT‑interval prolongation, which can lead to potentially life‑threatening arrhythmias. Rarely, severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome may occur. Patients should seek immediate medical attention if they experience chest pain, palpitations, severe abdominal pain, or signs of an allergic reaction.

Klacid Uno should not be used by individuals with a known hypersensitivity to clarithromycin, other macrolides, or any component of the formulation. It is also contraindicated in patients with a history of significant QT prolongation or those taking other medications that strongly prolong the QT interval. Caution is advised in severe hepatic impairment.