Product image of Klaira (Dienogest, Estradiol Valerate | Estradiol Valerate | Lactose Monohydrate) supplied by GNH India

Klaira

Active Ingredient:
Dienogest, Estradiol Valerate | Estradiol Valerate | Lactose Monohydrate
Origin:
EU

Klaira (Dienogest, Estradiol Valerate | Estradiol Valerate | Lactose Monohydrate)

Dienogest and Estradiol valerate, the active ingredients in Klaira, are a combined oral contraceptive presented as a tablet for oral use. They prevent pregnancy in women of reproductive age.

GNH India supplies Klaira as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bayer Spa

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Klaira, a combined oral contraceptive, is used to prevent pregnancy by inhibiting ovulation.

  • Contraception (prevention of pregnancy): provides reliable hormonal birth control for women of child‑bearing potential.

How It Works

  • Klaira combines dienogest, a progestogen, with estradiol valerate, an estrogen. The estrogen suppresses the mid‑cycle surge of luteinising hormone (LH) and follicle‑stimulating hormone (FSH), while the progestogen reinforces this suppression, preventing ovulation. The hormonal milieu also thickens cervical mucus and alters the endometrium, reducing the chance of fertilisation and implantation.

Side Effects

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: tension‑type or migraine‑like pain.
  • Breast tenderness: discomfort or swelling of the breasts.
  • Irregular bleeding: spotting or changes in menstrual flow.

Serious or Rare Side Effects

  • Deep vein thrombosis: blood clot formation in deep veins.
  • Severe allergic reaction: rash, swelling, or difficulty breathing.

Precautions & Warnings

Klaira should be used with caution and under medical supervision.

  • Contraindicated in pregnancy: must not be taken during pregnancy.
  • Contraindicated in active thromboembolic disease: avoid use if clotting disorders are present.
  • Avoid in smokers over 35 years: increased cardiovascular risk.
  • Monitor blood pressure regularly: hormonal contraceptives may elevate blood pressure.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Klaira may interact with other medicines, requiring attention to avoid reduced efficacy or increased risk.

Major Interactions (Avoid)

  • Antiepileptic enzyme inducers (e.g., carbamazepine, phenytoin): may lower contraceptive effectiveness.
  • Rifampin: reduces hormone levels, risking contraceptive failure.
  • St. John’s wort: herbal inducer that can diminish drug exposure.
  • Griseofulvin: antibiotic that may decrease hormone concentrations.

Moderate Interactions (Monitor Closely)

  • Antifungals (e.g., ketoconazole): can increase estrogen levels.
  • Selective serotonin reuptake inhibitors (SSRIs): may raise bleeding risk.
  • Hormone therapy (e.g., estrogen replacement): may augment overall estrogen exposure.

Frequently Asked Questions

Klaira is a combined oral contraceptive tablet that is prescribed to prevent pregnancy in women of reproductive age by suppressing ovulation and creating an environment that is unfavorable for fertilisation and implantation.

The estradiol component suppresses the mid‑cycle surge of luteinising hormone (LH) and follicle‑stimulating hormone (FSH), while dienogest, a progestogen, reinforces this suppression. Together they prevent ovulation, thicken cervical mucus, and alter the endometrium, reducing the likelihood of fertilisation and implantation.

The dosing regimen for Klaira is determined by the prescribing healthcare professional. Typically, it is taken as a daily oral tablet according to the schedule provided on the prescription label.

Klaira is contraindicated in pregnancy and must not be used by women who are pregnant or suspect they might be. It is also not recommended during breastfeeding unless the prescriber determines the benefits outweigh potential risks.

To order Klaira, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Klaira contains dienogest and estradiol valerate, offering a specific estrogen‑progestogen balance that may provide a different side‑effect profile compared with products containing ethinyl estradiol and other progestins. Clinical choice depends on individual risk factors, tolerability and physician preference.

Klaira tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the container tightly closed and out of reach of children.

Klaira is taken orally, usually once daily at the same time each day, with or without food, following the dosing schedule indicated by the prescriber.

Serious risks include venous thromboembolism, deep vein thrombosis, pulmonary embolism, stroke, myocardial infarction, and severe allergic reactions. Patients should seek immediate medical attention if they experience symptoms such as leg pain, shortness of breath, chest pain, or signs of an allergic reaction.

Klaira should not be used by women who are pregnant, have a history of thromboembolic disorders, are smokers over 35 years of age, have uncontrolled hypertension, have severe liver disease, or have known hypersensitivity to any of its ingredients.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.