Product image of Klaricid Adult (Clarithromycin) supplied by GNH India

Klaricid Adult

Active Ingredient:
Clarithromycin
Origin:
EU

Klaricid Adult (Clarithromycin)

Clarithromycin, the active ingredient in Klaricid Adult, is a macrolide antibiotic presented as an oral formulation for oral use. It treats bacterial infections in adult patients, including respiratory and skin infections.
GNH India supplies Klaricid Adult as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Mylan Products Limited

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Indications & Clinical Uses

Clarithromycin is a macrolide antibiotic used to treat infections caused by susceptible bacteria.

  • Community‑acquired pneumonia: effective treatment of bacterial pneumonia in adults.
  • Acute bacterial sinusitis: eradicates the causative organisms and relieves sinus inflammation.
  • Acute bacterial exacerbation of chronic bronchitis: reduces bacterial load and improves respiratory symptoms.
  • Skin and soft tissue infections: combats susceptible skin pathogens and promotes healing.
  • Helicobacter pylori eradication regimens: part of combination therapy to eliminate H. pylori infection.

How It Works

  • Clarithromycin binds to the 50S subunit of bacterial ribosomes, blocking the translocation step of protein synthesis. This inhibition prevents elongation of the peptide chain, halting bacterial growth and leading to a bacteriostatic effect against susceptible organisms.

Side Effects

Clarithromycin may cause a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, sometimes watery.
  • Abdominal pain: cramping or discomfort in the stomach area.
  • Taste disturbance: altered or metallic taste perception.

Serious or Rare Side Effects

  • Severe allergic reactions: rash, swelling, or anaphylaxis.
  • Clostridioides difficile‑associated diarrhea: severe colitis requiring medical attention.
  • QT interval prolongation: potential cardiac arrhythmias.
  • Hepatotoxicity: elevated liver enzymes or liver injury.

Precautions & Warnings

Before prescribing Klaricid Adult, consider the following safety measures.

  • Assess renal function: dose adjustment may be needed in renal impairment.
  • Monitor liver enzymes: watch for signs of hepatotoxicity during therapy.
  • Check for drug interactions: especially with agents that affect QT interval or CYP3A4 metabolism.
  • Avoid use in patients with known macrolide hypersensitivity: discontinue if allergic reaction occurs.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Clarithromycin interacts with several medicines; awareness of the interaction level guides management.

Major Interactions (Avoid)

  • Other macrolides (e.g., erythromycin): additive risk of QT prolongation.
  • Cisapride: may cause serious cardiac arrhythmias.
  • Pimozide: increased plasma concentrations leading to toxicity.
  • Theophylline: elevated levels can cause seizures or cardiac effects.

Moderate Interactions (Monitor Closely)

  • Warfarin: enhanced anticoagulant effect, monitor INR.
  • Statins (lovastatin, simvastatin): increased risk of myopathy, consider dose adjustment.
  • Carbamazepine: reduced clarithromycin exposure, may require efficacy monitoring.

Frequently Asked Questions

Klaricid Adult contains clarithromycin, a macrolide antibiotic indicated for treating bacterial infections such as community‑acquired pneumonia, acute bacterial sinusitis, exacerbations of chronic bronchitis, skin and soft‑tissue infections, and as part of Helicobacter pylori eradication regimens.

Clarithromycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, blocking peptide chain elongation. This action stops bacterial growth, providing a bacteriostatic effect against susceptible organisms.

The dosage of Klaricid Adult is determined by the prescribing clinician based on the infection being treated, patient age, weight, renal and hepatic function, and local prescribing guidelines. Patients should follow the prescriber’s instructions precisely.

Safety of clarithromycin in pregnancy or while breastfeeding has not been definitively established. Clinicians should weigh potential benefits against possible risks and consider alternative therapies when appropriate.

To order Klaricid Adult, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Clarithromycin offers a broader spectrum against certain respiratory pathogens and better tissue penetration compared with older macrolides like erythromycin. It also has a more convenient dosing schedule, though drug‑interaction potential remains significant and must be managed.

Store Klaricid Adult at ambient temperature, below 25 °C, in the original packaging. Protect it from moisture, heat and direct sunlight to maintain stability and potency.

Klaricid Adult is taken orally, usually with or without food as directed by the prescriber. The tablets or suspension should be swallowed whole or measured accurately, and the full prescribed course should be completed.

Serious risks include severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, QT interval prolongation leading to cardiac arrhythmias, and hepatotoxicity. Patients should seek immediate medical attention if they experience symptoms like rash, persistent diarrhea, chest pain, or jaundice.

Klaricid Adult should not be used by individuals with known hypersensitivity to clarithromycin, other macrolides, or any component of the formulation. Caution is also advised for patients with significant hepatic impairment, prolonged QT interval, or those taking contraindicated medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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