Product image of Klarmin (Clarithromycin) supplied by GNH India

Klarmin

Active Ingredient:
Clarithromycin
Origin:
EU

Klarmin (Clarithromycin)

Clarithromycin, the active ingredient in Klarmin, is a macrolide antibiotic presented as a tablet for oral use. It treats bacterial infections such as community‑acquired pneumonia, acute bacterial sinusitis, chronic bronchitis exacerbations, and skin and soft‑tissue infections in adults and children as prescribed.

GNH India supplies Klarmin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bausch Health Ireland Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Clarithromycin acts on bacterial protein synthesis, making it effective for several respiratory and skin infections.

  • Community‑acquired pneumonia: eradicates causative bacteria and improves clinical recovery.
  • Acute bacterial sinusitis: reduces bacterial load and alleviates sinus inflammation.
  • Acute exacerbations of chronic bronchitis: shortens illness duration and prevents complications.
  • Skin and soft‑tissue infections: treats staphylococcal and streptococcal skin infections.

How It Works

  • Clarithromycin binds to the 50S subunit of bacterial ribosomes, blocking the translocation step of protein synthesis. This inhibition prevents elongation of the peptide chain, halting bacterial growth and leading to a bacteriostatic effect against susceptible organisms.

Side Effects

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools that may be watery.
  • Abdominal pain: cramping or discomfort in the abdomen.
  • Taste disturbance: altered sense of taste, often metallic.
  • Headache: mild to moderate head pain.
  • Vomiting: occasional expulsion of stomach contents.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction with rash, swelling, and breathing difficulty.
  • Clostridioides difficile‑associated diarrhea: severe colitis requiring medical attention.
  • Hepatotoxicity: elevated liver enzymes or jaundice.
  • QT prolongation: heart rhythm changes that may lead to arrhythmia.
  • Stevens‑Johnson syndrome: rare skin blistering disorder.
  • Severe cardiac arrhythmias: irregular heartbeats that can be life‑threatening.

Precautions & Warnings

Clarithromycin should be used with caution in specific patient groups and clinical situations.

  • Pregnancy: Category B; prescribe only when benefit outweighs potential risk.
  • Renal impairment: dose adjustment may be necessary; monitor kidney function.
  • Hepatic impairment: monitor liver enzymes; consider dose reduction.
  • Drug interactions: avoid concomitant use with strong CYP3A4 inhibitors.
  • QT prolongation risk: monitor ECG in patients with cardiac history.
  • Store at ambient temperature (below 25°C): keep in original packaging, protect from moisture.

Avoid Interactions

Clarithromycin can interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Erythromycin: additive risk of QT prolongation.
  • Cisapride: may cause serious cardiac arrhythmias.
  • Astemizole: increased risk of QT prolongation.
  • Terfenadine: heightened potential for cardiac events.

Moderate Interactions (Monitor Closely)

  • Simvastatin: elevated plasma levels may increase myopathy risk.
  • Warfarin: enhanced anticoagulant effect; monitor INR closely.

Frequently Asked Questions

Klarmin contains clarithromycin, a macrolide antibiotic indicated for community‑acquired pneumonia, acute bacterial sinusitis, acute exacerbations of chronic bronchitis, and skin and soft‑tissue infections caused by susceptible bacteria.

Clarithromycin binds to the 50S ribosomal subunit of bacteria, inhibiting protein synthesis. This blocks the translocation step of peptide chain elongation, resulting in a bacteriostatic effect that stops bacterial growth.

The dosage of Klarmin is determined by the prescribing clinician based on the specific infection, patient age, weight, renal and hepatic function, and local treatment guidelines. Patients should follow the prescriber’s instructions precisely.

Clarithromycin is classified as Pregnancy Category B, indicating that animal studies have not shown risk but there are limited human data. It may be used during pregnancy only if the potential benefit justifies the risk. Use while breastfeeding only if recommended by a healthcare professional.

To order Klarmin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Klarmin (clarithromycin) offers a broader spectrum against certain Gram‑positive and atypical organisms compared with erythromycin, and it has a longer half‑life allowing twice‑daily dosing. However, drug‑interaction potential, especially with CYP3A4 substrates, may differ and should be evaluated by the prescriber.

Klarmin tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect from moisture and light. Do not store in areas of high humidity or extreme heat.

Klarmin is taken orally, usually with or without food as directed by the prescriber. The tablets should be swallowed whole with a full glass of water and not chewed or crushed unless specifically advised.

Serious risks include severe allergic reactions (anaphylaxis), Clostridioides difficile‑associated colitis, hepatotoxicity, QT interval prolongation leading to arrhythmias, and rare skin disorders such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience symptoms like rash, persistent diarrhea, jaundice, or irregular heartbeat.

Klarmin should be avoided in patients with known hypersensitivity to clarithromycin or other macrolides, those with a history of prolonged QT interval, and individuals taking contraindicated medications such as cisapride, astemizole, or terfenadine. Clinicians should assess renal and hepatic function before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.