Product image of Klaximol (Amoxicillin, Clavulanic Acid) supplied by GNH India

Klaximol

Active Ingredient:
Amoxicillin, Clavulanic Acid
Origin:
EU

Klaximol (Amoxicillin, Clavulanic Acid)

Amoxicillin/clavulanic acid, the active ingredient in Klaximol, is a beta‑lactam antibiotic with beta‑lactamase inhibitor presented as an oral tablet for systemic use. It treats a range of bacterial infections in adults and children when prescribed by a healthcare professional.

GNH India supplies Klaximol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aristo Pharma Gmbh (Art 57)

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Indications & Clinical Uses

Klaximol is used to treat bacterial infections affecting several organ systems.

  • Sinusitis: reduces bacterial load and relieves sinus inflammation.
  • Otitis media: clears middle‑ear infection and improves hearing symptoms.
  • Pneumonia: eradicates causative pathogens in community‑acquired lung infection.
  • Urinary tract infections: eliminates uropathogens and resolves urinary symptoms.
  • Skin and soft tissue infections: treats cellulitis and wound infections caused by susceptible bacteria.

How It Works

  • Amoxicillin binds to penicillin‑binding proteins, inhibiting the final step of bacterial cell‑wall peptidoglycan synthesis, which leads to cell lysis. Clavulanic acid acts as a suicide inhibitor of bacterial beta‑lactamases, protecting amoxicillin from enzymatic degradation and extending its antibacterial spectrum against beta‑lactamase‑producing organisms.

Side Effects

Adverse reactions may occur with any antibiotic therapy.

Common Side Effects

  • Diarrhea: mild to moderate loose stools.
  • Nausea: transient feeling of queasiness.
  • Rash: erythematous skin eruption.
  • Headache: mild to moderate head discomfort.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction with airway compromise.
  • Stevens‑Johnson syndrome: rare mucocutaneous blistering disorder.
  • Hepatotoxicity: elevated liver enzymes or jaundice.
  • Clostridioides difficile colitis: severe diarrhea due to bacterial overgrowth.

Precautions & Warnings

Before prescribing Klaximol, consider patient‑specific factors and safety measures.

  • Allergy assessment: avoid in patients with known hypersensitivity to penicillins or clavulanic acid.
  • Renal function: adjust dose in severe renal impairment.
  • Hepatic disease: monitor liver enzymes in patients with liver dysfunction.
  • Pregnancy and lactation: use only if clearly needed after risk‑benefit evaluation.
  • Drug interactions: review concomitant medications for potential interactions.
  • Store at ambient temperature: keep below 25 °C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Klaximol may alter the efficacy or safety of other medicines.

Major Interactions (Avoid)

  • Allopurinol: increased risk of rash.
  • Methotrexate: reduced clearance leading to toxicity.
  • Oral contraceptives: decreased hormonal effectiveness.

Moderate Interactions (Monitor Closely)

  • Warfarin: potential enhancement of anticoagulant effect.
  • Probenecid: may increase amoxicillin plasma levels.
  • Antacids containing aluminum or magnesium: may reduce absorption if taken simultaneously.

Frequently Asked Questions

Klaximol is prescribed for bacterial infections such as acute sinusitis, otitis media, community‑acquired pneumonia, uncomplicated urinary tract infections, and skin or soft‑tissue infections caused by susceptible organisms. The choice of therapy depends on culture results and clinical judgment.

Amoxicillin interferes with bacterial cell‑wall synthesis by binding to penicillin‑binding proteins, while clavulanic acid inhibits beta‑lactamase enzymes that some bacteria produce to inactivate amoxicillin. This combination broadens the antibacterial spectrum and enhances bacterial killing.

The dosage of Klaximol is individualized by the prescribing clinician based on the infection type, severity, patient age, weight, and renal function. Healthcare providers determine the appropriate strength, frequency, and duration of therapy.

Safety data for amoxicillin/clavulanic acid in pregnancy are limited, and the product is classified as pregnancy category unknown. It should be used only when clearly needed, after weighing potential benefits against risks. Breastfeeding mothers should consult their physician, as small amounts may be excreted in milk.

To place an order, submit an enquiry on the Klaximol product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Klaximol combines amoxicillin with clavulanic acid, offering protection against beta‑lactamase‑producing bacteria that can inactivate amoxicillin alone. This broader spectrum makes it useful for infections where resistance mechanisms are suspected, whereas plain amoxicillin may be sufficient for beta‑lactamase‑negative organisms.

Klaximol tablets should be stored at ambient temperature, preferably below 25 °C. Keep them in the original blister pack, protect from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Klaximol is taken orally, usually with a full glass of water. It can be taken with or without food, but consistency with meals may reduce gastrointestinal upset. Patients should follow the prescribing clinician’s instructions regarding timing and duration.

Serious adverse reactions include anaphylaxis, Stevens‑Johnson syndrome, severe hepatic injury, and Clostridioides difficile‑associated colitis. Any signs of severe rash, difficulty breathing, jaundice, or persistent diarrhea warrant immediate medical attention.

Klaximol is contraindicated in individuals with a known hypersensitivity to amoxicillin, clavulanic acid, or other beta‑lactam antibiotics. Patients with a history of severe allergic reactions to penicillins should avoid this medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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