Product image of Klimadynon (Dry Extract From Cimicifuga Racemosa (L.) Nutt., Rhizoma (Black Cohosh) (5-10:1), Extraction Solvent) supplied by GNH India

Klimadynon

Active Ingredient:
Dry Extract From Cimicifuga Racemosa (L.) Nutt., Rhizoma (Black Cohosh) (5-10:1), Extraction Solvent
Origin:
EU

Klimadynon (Dry Extract From Cimicifuga Racemosa (L.) Nutt., Rhizoma (Black Cohosh) (5-10:1), Extraction Solvent)

Dry Extract From Cimicifuga Racemosa (L.) Nutt., Rhizoma (Black Cohesh) (5-10:1), Extraction Solvent, the active ingredient in Klimadynon, is a herbal botanical presented as a dry extract for oral use. It is traditionally used to support women’s health, particularly during the menopausal transition. GNH India supplies Klimadynon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bionorica Se

1
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Indications & Clinical Uses

  • Klimadynon, a black cohosh extract, is traditionally used to address hormonal‑related conditions in women.
  • Menopausal symptoms: may help reduce hot flashes and night sweats.
  • Premenstrual syndrome (PMS): may alleviate breast tenderness and mood swings.
  • Menstrual discomfort: may support regularity and reduce cramps.

How It Works

  • The dry extract of Cimicifuga racemosa contains phytochemicals such as triterpene glycosides, flavonoids and phenolic acids that are thought to modulate serotonergic pathways and interact with estrogen receptors. These actions may influence neuroendocrine regulation of temperature, mood and uterine smooth‑muscle activity, providing symptomatic relief in hormone‑related conditions.

Side Effects

Common Side Effects

  • Mild gastrointestinal upset (nausea, abdominal discomfort).
  • Headache.
  • Dizziness or light‑headedness.
  • Minor skin irritation at the site of contact.
  • Fatigue.

Serious or Rare Side Effects

  • Elevated liver enzymes or hepatitis.
  • Severe allergic reaction (anaphylaxis, rash, swelling).
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Unexplained bleeding or bruising.
  • Acute cardiovascular events (rare).

Precautions & Warnings

Klimadynon should be used with professional guidance, especially in special populations.

  • Pregnancy: avoid use due to insufficient safety data.
  • Breastfeeding: avoid until safety is established.
  • Liver disease: use with caution and monitor liver function.
  • Concomitant hormone therapy: discuss potential additive effects with a clinician.
  • Known allergy to black cohosh: discontinue immediately.

Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Klimadynon may interact with several medication classes.

Major Interactions (Avoid)

  • Concurrent estrogen therapy: may increase hormonal effects.
  • Anticoagulants or antiplatelet agents: may heighten bleeding risk.

Moderate Interactions (Monitor Closely)

  • CYP450 substrates (e.g., certain statins): may alter drug metabolism.
  • SSRIs or other serotonergic agents: may enhance serotonergic activity.
  • Diuretics: may affect electrolyte balance.

Frequently Asked Questions

Klimadynon contains a dry extract of black cohosh (Cimicifuga racemosa) and is traditionally used to support women during menopause, helping to reduce hot flashes, night sweats, and other hormonal‑related discomforts. It may also be used for premenstrual syndrome and menstrual irregularities, although clinical evidence varies.

The extract provides phytochemicals that can influence serotonergic pathways and interact with estrogen receptors. By modulating these neuroendocrine signals, the product may help stabilize temperature regulation, mood, and uterine smooth‑muscle activity, which are often disrupted during hormonal transitions.

The appropriate dose of Klimadynon is determined by the prescribing healthcare professional based on the individual’s condition, age, and overall health. Patients should follow the specific instructions provided by their clinician and not adjust the dose without medical advice.

Safety data for Klimadynon in pregnancy and lactation are limited. Current recommendations advise avoiding its use during pregnancy and while breastfeeding until more robust safety information becomes available. Women who are pregnant, planning pregnancy, or nursing should discuss alternatives with their healthcare provider.

To request Klimadynon, visit the product page on gnhindia.com, enter the required quantity, and submit the enquiry form. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Klimadynon’s active ingredient is a standardized black cohosh extract, which differs from phytoestrogen‑based supplements such as soy isoflavones. While both aim to alleviate menopausal symptoms, black cohosh is thought to act primarily through serotonergic modulation rather than direct estrogenic activity, offering an alternative mechanism for symptom relief.

Klimadynon should be stored at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, direct sunlight, and excessive heat to maintain its stability and potency over time.

Klimadynon is taken orally, typically as a capsule or tablet, depending on the specific commercial preparation. The exact administration schedule—such as frequency and timing—should be prescribed by a qualified healthcare professional and taken with water as directed.

Serious risks, though rare, include liver toxicity (elevated enzymes or hepatitis) and severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they notice signs of liver dysfunction, rash, swelling, or breathing difficulties while using the product.

Individuals with known hypersensitivity to black cohosh, those with active liver disease, pregnant or breastfeeding women, and patients taking estrogen‑containing therapies without medical supervision should avoid Klimadynon. Consultation with a healthcare provider is essential before starting the product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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