Product image of Klimadynon (Dry Extract From Cimicifuga Racemosa (L.) Nutt., Rhizoma (Black Cohosh) (5-10:1), Extraction Solvent) supplied by GNH India

Klimadynon

Active Ingredient:
Dry Extract From Cimicifuga Racemosa (L.) Nutt., Rhizoma (Black Cohosh) (5-10:1), Extraction Solvent
Origin:
EU

Klimadynon (Dry Extract From Cimicifuga Racemosa (L.) Nutt., Rhizoma (Black Cohosh) (5-10:1), Extraction Solvent)

Cimicifuga racemosa dry extract, the active ingredient in Klimadynon, is a herbal botanical presented as a dry extract for oral use. It is traditionally employed to support women experiencing menopausal symptoms, particularly vasomotor disturbances such as hot flashes and night sweats. Klimadynon is manufactured in the European Union and complies with applicable quality standards for botanical medicines.

GNH India supplies Klimadynon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bionorica Se

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Klimadynon, containing black cohosh dry extract, is used primarily in the management of menopausal symptoms.

  • Menopausal hot flashes: reduction in frequency and intensity of episodes.
  • Night sweats: alleviation of disruptive nocturnal sweating.
  • Mood swings associated with menopause: support for emotional stability.
  • Sleep disturbances during menopause: improvement in sleep quality.
  • Minor vaginal dryness: modest relief of discomfort.

How It Works

  • The dry extract of Cimicifuga racemosa contains phytoestrogenic triterpene glycosides and flavonoids that can bind to estrogen receptors and modulate serotonergic pathways in the central nervous system. These actions are thought to stabilize hypothalamic thermoregulatory centers, thereby reducing vasomotor symptoms such as hot flashes and night sweats, while also influencing mood-related neurotransmission.

Side Effects

Klimadynon is generally well tolerated, but some users may experience adverse reactions.

Common Side Effects

  • Mild gastrointestinal upset, such as nausea or stomach discomfort.
  • Headache.
  • Dizziness.
  • Skin rash or mild itching.
  • Fatigue.
  • Mild insomnia.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis).
  • Significant liver enzyme elevation.
  • Unexplained bleeding or bruising.
  • Thromboembolic events.
  • Severe hypertension.
  • Acute liver injury.

Precautions & Warnings

When considering Klimadynon, certain precautions should be observed.

  • Pregnancy: avoid use unless specifically advised by a healthcare professional.
  • Breastfeeding: exercise caution and consult a physician before use.
  • Liver disease: monitor liver function during therapy.
  • Concurrent hormonal therapy: assess potential additive estrogenic effects.
  • Known allergy to black cohosh: contraindicated.
  • Store at ambient temperature below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Klimadynon may interact with other medicines; awareness of these interactions helps ensure safe use.

Major Interactions (Avoid)

  • Concomitant estrogen‑containing therapies: may increase overall estrogenic activity.
  • Anticoagulants (e.g., warfarin): potential for enhanced bleeding risk.
  • Selective serotonin reuptake inhibitors (SSRIs): possible serotonin syndrome.

Moderate Interactions (Monitor Closely)

  • Hormonal contraceptives: may alter contraceptive effectiveness.
  • Lithium: potential increase in lithium serum levels.
  • CYP450 substrate drugs: possible modulation of metabolism leading to altered drug concentrations.

Frequently Asked Questions

Klimadynon is a herbal product that contains a dry extract of Cimicifuga racemosa, commonly known as black cohosh. It is primarily used to help alleviate vasomotor symptoms associated with menopause, such as hot flashes, night sweats, and related mood changes.

The extract contains phytoestrogenic compounds and triterpene glycosides that can interact with estrogen receptors and influence serotonergic pathways in the brain. This dual activity is believed to stabilize the hypothalamic temperature regulation center, reducing the frequency and severity of hot flashes and improving mood stability.

The appropriate dose of Klimadynon is determined by the prescribing healthcare professional based on individual needs, severity of symptoms, and overall health status. Patients should follow the prescriber’s instructions and not adjust the dose without medical guidance.

Safety of black cohosh extracts during pregnancy and lactation has not been conclusively established. It is generally recommended to avoid Klimadynon during pregnancy and to use it with caution while breastfeeding, unless a qualified healthcare provider advises otherwise.

To order Klimadynon, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Klimadynon offers a botanical alternative to hormone‑replacement therapy (HRT) and synthetic pharmaceuticals. While HRT directly supplies estrogen, black cohosh works through phytoestrogenic and serotonergic mechanisms, which may be preferred by patients seeking a non‑hormonal option. Clinical efficacy varies, and individual response should be discussed with a healthcare professional.

Klimadynon should be stored at ambient temperature below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Klimadynon is taken orally, typically in tablet or capsule form, as directed by a healthcare provider. It is usually swallowed with water, and the dosing schedule (once or twice daily) is individualized based on the prescriber’s recommendation.

Serious risks, although rare, include severe allergic reactions such as anaphylaxis, significant liver enzyme elevations indicating potential liver injury, and rare cardiovascular events like hypertension or thromboembolic complications. Patients should seek immediate medical attention if they experience symptoms such as rash, jaundice, unexplained bruising, or sudden severe headache.

Individuals with a known allergy to black cohosh or any component of the formulation should avoid Klimadynon. It is also contraindicated for women who are pregnant, those with severe liver disease, and patients taking certain estrogen‑containing medications or anticoagulants without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.