Product image of Klimadynon (Dry Extract From Cimicifuga Racemosa (L.) Nutt., Rhizoma (Black Cohosh) (5-10:1), Extraction Solvent) supplied by GNH India

Klimadynon

Active Ingredient:
Dry Extract From Cimicifuga Racemosa (L.) Nutt., Rhizoma (Black Cohosh) (5-10:1), Extraction Solvent
Origin:
EU

Klimadynon (Dry Extract From Cimicifuga Racemosa (L.) Nutt., Rhizoma (Black Cohosh) (5-10:1), Extraction Solvent)

Dry Extract From Cimicifuga Racemosa (Black Cohosh), the active ingredient in Klimadynon, is a herbal botanical presented as a dry extract for oral use. It has been traditionally employed to support women experiencing menopausal vasomotor symptoms and related discomfort. The extract is standardized to a typical ratio of 5‑10:1, ensuring consistent phytochemical content across batches.

GNH India supplies Klimadynon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU GMP guidelines and provides regulatory documentation for global distribution, supported by robust quality assurance and traceability measures.

Manufacturer / TM Owner

Bionorica Se

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Klimadynon, a black cohosh dry extract, is used primarily in the management of menopausal‑related conditions.

  • Menopausal vasomotor symptoms: helps reduce frequency and intensity of hot flashes and night sweats.
  • Menstrual discomfort: may alleviate irregular cycles and associated pelvic pain.
  • Mood disturbances linked to menopause: can support emotional stability and reduce irritability.

How It Works

  • The exact mechanism of black cohosh is not fully elucidated, but research suggests that its phytochemicals interact with serotonergic receptors in the central nervous system and may exert weak estrogenic activity on peripheral tissues. These actions are thought to modulate thermoregulatory pathways and influence neurotransmitter balance, contributing to relief of vasomotor and mood symptoms associated with menopause.

Side Effects

Adverse reactions to Klimadynon are generally mild, but clinicians should be aware of both common and rare events.

Common Side Effects

  • Mild gastrointestinal upset: nausea, abdominal discomfort, or diarrhea.
  • Headache: transient mild to moderate headache.
  • Dizziness: occasional light‑headedness.
  • Skin rash: mild erythema or itching.

Serious or Rare Side Effects

  • Liver injury: signs of hepatitis or elevated liver enzymes.
  • Severe allergic reaction: anaphylaxis, angioedema, or bronchospasm.
  • Skin disorders: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

When prescribing Klimadynon, consider the following precautions to ensure safe use.

  • Liver function assessment: evaluate hepatic health before initiating therapy.
  • Hypersensitivity: avoid if the patient has known allergy to black cohosh.
  • Hormone‑sensitive conditions: use with caution in estrogen‑dependent tumors.
  • Anticoagulant therapy: monitor bleeding risk when combined with warfarin or similar agents.
  • Pregnancy and lactation: contraindicated due to insufficient safety data.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Klimadynon may interact with several medicines; awareness of interaction severity guides clinical decisions.

Major Interactions (Avoid)

  • Warfarin or other anticoagulants: may enhance bleeding risk.
  • Hormonal contraceptives or estrogen therapy: potential additive estrogenic effects.

Moderate Interactions (Monitor Closely)

  • Selective serotonin reuptake inhibitors (SSRIs): possible serotonergic synergy.
  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): increased gastrointestinal irritation.
  • Antihypertensive agents: may modestly affect blood pressure control.

Frequently Asked Questions

Klimadynon is a dry extract of black cohosh that is traditionally used to alleviate menopausal vasomotor symptoms such as hot flashes and night sweats, as well as to support menstrual comfort and mood stability during the perimenopausal period.

The black cohosh extract contains phytochemicals that appear to modulate serotonergic pathways in the brain and may exert weak estrogen‑like activity on peripheral tissues. These actions help regulate body temperature and influence neurotransmitter balance, which can reduce hot flashes and improve emotional well‑being.

The appropriate dose of Klimadynon is determined by the prescribing healthcare professional based on the individual’s clinical condition, age, and response. No standardized regimen is provided here; the prescriber will specify the exact amount and frequency.

Safety data for black cohosh use in pregnancy or while nursing are limited. Because of the lack of conclusive evidence, Klimadynon is generally not recommended for pregnant or breastfeeding women.

To request Klimadynon, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Klimadynon offers a botanical alternative to hormone replacement therapy (HRT). While HRT provides direct estrogen supplementation, black cohosh works through indirect pathways and may be preferred by patients seeking non‑hormonal options. Efficacy varies, and individual response should be evaluated by a clinician.

Store Klimadynon at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, direct sunlight and extreme heat to maintain stability.

Klimadynon is taken orally, usually with a glass of water. It can be taken with or without food, according to the prescriber’s instructions, and should be swallowed whole rather than chewed.

The most serious adverse events reported with black cohosh include potential liver injury, such as hepatitis or elevated liver enzymes, and severe allergic reactions like anaphylaxis or Stevens‑Johnson syndrome. Patients should be monitored for signs of hepatic dysfunction or hypersensitivity.

Klimadynon should be avoided by individuals with known hypersensitivity to black cohosh, those with active liver disease, patients taking anticoagulants without medical supervision, and women who are pregnant, breastfeeding, or have estrogen‑dependent cancers.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Dry Extract From Cimicifuga Racemosa (L.) Nutt., Rhizoma (Black Cohosh) (5-10:1), Extraction Solvent

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT