Kliogest (Norethisterone Acetate, Estradiol)

Norethisterone acetate acts as a progestogen, suppressing the mid‑cycle surge of luteinising hormone (LH) and follicle‑stimulating hormone (FSH), which blocks ovulation. Estradiol, an estrogen, stabilises the endometrial lining and contributes to negative feedback on the hypothalamic‑pituitary axis, enhancing cycle regularity.

The specific dosing regimen for Kliogest is determined by the prescribing healthcare professional based on individual patient factors. Patients should follow the prescriber’s instructions and not alter the dose without medical advice.

Kliogest is intended for use as a contraceptive and is not recommended for women who are pregnant or planning to become pregnant. It is generally contraindicated during breastfeeding unless the prescriber determines that the benefits outweigh the risks. Consultation with a healthcare provider is essential.

To order Kliogest, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Kliogest contains the same class of active ingredients—an estrogen (estradiol) and a progestogen (norethisterone acetate)—as many other combined oral contraceptives. Its efficacy and safety profile are comparable, though individual formulations may differ in hormone doses, which can influence side‑effect frequency and specific clinical preferences.

Kliogest tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged.

Kliogest is taken orally, usually once daily at the same time each day, as directed by the prescriber. Consistent daily intake helps maintain hormone levels and maximises contraceptive effectiveness.

The most serious risks include venous thromboembolism, pulmonary embolism, stroke, myocardial infarction, severe hypertension, and rare liver disorders such as hepatic adenoma. Patients should seek immediate medical attention if they experience symptoms such as unexplained leg pain, chest pain, severe headache, or visual changes.

Kliogest is contraindicated in women with a history of thromboembolic disorders, active liver disease, known or suspected breast cancer, uncontrolled hypertension, or those who are pregnant or breastfeeding. It should also be avoided by smokers over 35 years of age and by individuals taking certain interacting medications without medical supervision.