Kliogest (Norethisterone Acetate, Estradiol)

Norethisterone acetate suppresses the hypothalamic‑pituitary‑ovarian axis, lowering LH and FSH release and thereby preventing ovulation. Estradiol stabilises the endometrial lining and thickens cervical mucus, creating a hostile environment for sperm and implantation.

The specific dosing regimen for Kliogest is determined by the prescribing healthcare professional based on the product’s formulation and the patient’s clinical needs. Patients should follow the prescriber’s instructions and not alter the dose on their own.

Kliogest is contraindicated in pregnancy (Category X) because it may harm the fetus. It is also not recommended while breastfeeding, as hormonal components can pass into breast milk and affect the infant. Women should use alternative contraception if they become pregnant or plan to breastfeed.

To request Kliogest, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Kliogest contains norethisterone acetate and estradiol, whereas many other combined pills use ethinyl‑estradiol as the estrogen component. The estradiol in Kliogest may offer a more physiological estrogen profile, potentially resulting in different side‑effect patterns, but efficacy in preventing pregnancy remains comparable.

Kliogest tablets should be stored at room temperature, below 25 °C, in the original container to protect from moisture and light. Keep the medication out of reach of children and do not use after the expiry date.

Kliogest is taken orally, usually once daily at the same time each day, as directed by the prescriber. The tablet is swallowed whole with water and should not be split, crushed, or chewed unless specifically instructed.

Serious risks include thromboembolic events such as deep‑vein thrombosis or pulmonary embolism, severe hypertension, liver dysfunction, and rare cases of stroke or visual disturbances. Patients should seek immediate medical attention if they experience unexplained leg pain, severe headache, visual changes, or sudden swelling.

Kliogest should not be used by women who are pregnant, have a known clotting disorder, uncontrolled hypertension, active liver disease, breast cancer, or who smoke heavily and are over 35 years of age. It is also contraindicated in individuals with known hypersensitivity to any component of the product.