Product image of Klopidogrel Pharmas (Clopidogrel) supplied by GNH India

Klopidogrel Pharmas

Active Ingredient:
Clopidogrel
Origin:
EU

Klopidogrel Pharmas (Clopidogrel)

Clopidogrel, the active ingredient in Klopidogrel Pharmas, is a P2Y12 receptor antagonist presented as a tablet for oral use. It helps prevent thrombotic events in patients with recent myocardial infarction, prior ischemic stroke or transient ischemic attack, and established peripheral arterial disease.

GNH India supplies Klopidogrel Pharmas as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pharmas

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Clopidogrel acts on platelet aggregation pathways to reduce the risk of arterial thrombotic events. It is indicated for:

  • Recent myocardial infarction: lowers the chance of cardiovascular death, recurrent MI or stroke.
  • Ischemic stroke or transient ischemic attack: reduces the risk of a subsequent stroke.
  • Peripheral arterial disease: decreases major adverse limb events and cardiovascular complications.

How It Works

  • Clopidogrel is an irreversible inhibitor of the platelet P2Y12 ADP receptor. By blocking this receptor, it prevents ADP‑mediated activation of the glycoprotein IIb/IIIa complex, thereby inhibiting platelet aggregation and reducing thrombus formation in arterial circulation.

Side Effects

Clopidogrel may cause a range of adverse reactions. Patients should be aware of both common and serious possibilities.

Common Side Effects

  • Bleeding gums
  • Easy bruising
  • Nausea
  • Diarrhea
  • Headache
  • Skin rash

Serious or Rare Side Effects

  • Intracranial or gastrointestinal hemorrhage
  • Severe thrombocytopenia
  • Anaphylactic or severe allergic reactions
  • Liver enzyme elevation
  • Thrombotic thrombocytopenic purpura (TTP)

Precautions & Warnings

Before prescribing clopidogrel, clinicians should evaluate individual risk factors and monitor patients closely.

  • Assess bleeding risk: review history of hemorrhage or surgery.
  • Monitor platelet function: consider laboratory testing if unexpected bleeding occurs.
  • Avoid in active pathological bleeding: discontinue if severe bleeding develops.
  • Caution with hepatic impairment: dose adjustment may be required.
  • Review concomitant drugs: anticoagulants, NSAIDs and other antiplatelets increase bleeding risk.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Clopidogrel interacts with several drug classes; some combinations should be avoided while others require careful monitoring.

Major Interactions (Avoid)

  • Warfarin: markedly increased bleeding risk.
  • Other antiplatelet agents (aspirin, ticagrelor): additive hemorrhagic effect.
  • CYP2C19 inhibitors (omeprazole, fluconazole): may raise clopidogrel plasma levels.
  • NSAIDs (ibuprofen, naproxen): heightened gastrointestinal bleeding.
  • Heparin or low‑molecular‑weight heparin: synergistic anticoagulation.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (rifampin, carbamazepine): may reduce antiplatelet efficacy.
  • SSRIs (fluoxetine, sertraline): modest increase in bleeding tendency.
  • ACE inhibitors: monitor for hypotension when combined with antiplatelet therapy.

Frequently Asked Questions

Klopidogrel Pharmas contains clopidogrel, an antiplatelet medication used to reduce the risk of serious cardiovascular events. It is prescribed for patients who have had a recent myocardial infarction, those with a history of ischemic stroke or transient ischemic attack, and individuals with established peripheral arterial disease to prevent further clot‑related complications.

Clopidogrel irreversibly blocks the platelet P2Y12 ADP receptor, which is essential for ADP‑mediated platelet activation and aggregation. By inhibiting this pathway, the drug reduces the ability of platelets to clump together, thereby lowering the likelihood of arterial thrombus formation that can lead to heart attacks, strokes, or limb‑ischaemia.

The dosage of Klopidogrel Pharmas is determined by the prescribing healthcare professional based on the patient’s specific clinical situation, renal and hepatic function, and concomitant medications. Patients should follow the exact regimen provided by their physician and not adjust the dose on their own.

The safety of clopidogrel in pregnancy and lactation has not been definitively established, and it is classified as having an unknown pregnancy category. Healthcare providers will weigh potential benefits against possible risks before prescribing it to pregnant or nursing mothers, and alternative therapies may be considered when appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the sales team provides pricing, availability, shipping details (including any cold‑chain requirements), and assists with import documentation.

Clopidogrel belongs to the thienopyridine class and is a P2Y12 receptor antagonist, similar to ticagrelor and prasugrel. Compared with aspirin, clopidogrel provides more potent inhibition of platelet aggregation without affecting cyclo‑oxygenase pathways. Relative to newer agents, clopidogrel has a longer track record, a once‑daily dosing schedule, and a lower cost, but its activation depends on CYP2C19 metabolism, which can affect efficacy in certain patients.

Store Klopidogrel Pharmas at room temperature, preferably below 25 °C. Keep the tablets in the original blister pack or container, protect them from moisture, excessive heat, and direct sunlight to maintain stability and potency throughout the shelf life.

Klopidogrel Pharmas is taken orally, usually with a glass of water. The tablet should be swallowed whole and can be taken with or without food, unless the prescribing physician advises otherwise. Patients should not crush, chew, or split the tablet unless instructed to do so.

The most serious risks include severe or life‑threatening bleeding such as intracranial hemorrhage, gastrointestinal bleeding, and bleeding that requires transfusion or surgery. Rare but critical reactions can involve thrombocytopenia, allergic anaphylaxis, and thrombotic thrombocytopenic purpura. Patients should seek immediate medical attention if they experience unusual bruising, blood in stool or urine, or signs of an allergic reaction.

Clopidogrel is contraindicated in individuals with active pathological bleeding, known hypersensitivity to clopidogrel or any component of the formulation, and patients with severe hepatic impairment. Caution is also advised for those with a history of hemorrhagic stroke, uncontrolled hypertension, or concurrent use of strong anticoagulants without appropriate medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.