Product image of Kloramfenikol Minims Bausch + Lomb Ireland Limited (Chloramphenicol) supplied by GNH India

Kloramfenikol Minims Bausch + Lomb Ireland Limited

Active Ingredient:
Chloramphenicol
Origin:
EU

Kloramfenikol Minims Bausch + Lomb Ireland Limited (Chloramphenicol)

Chloramphenicol, the active ingredient in Kloramfenikol Minims, is an amphenicol presented as an ophthalmic solution for ocular use. It treats bacterial conjunctivitis and other ocular surface infections in patients requiring topical antibiotic therapy.

GNH India supplies Kloramfenikol Minims as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bausch + Lomb Ireland Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Chloramphenicol is an antibiotic used to treat bacterial infections of the eye.

  • Bacterial conjunctivitis: reduces bacterial load, relieving redness, discharge and discomfort.
  • Ocular surface infection: eradicates susceptible organisms and supports healing of corneal lesions.
  • Post‑operative ocular prophylaxis: prevents bacterial contamination after eye surgery.

How It Works

  • Chloramphenicol inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, blocking peptide bond formation. This action halts bacterial growth and leads to bacteriostatic effects against a broad range of Gram‑positive and Gram‑negative ocular pathogens, allowing the host immune system to clear the infection.

Side Effects

Adverse reactions may occur with topical chloramphenicol use.

Common Side Effects

  • Stinging or burning sensation on instillation.
  • Temporary blurred vision.
  • Mild eye irritation or redness.
  • Localized allergic contact dermatitis.

Serious or Rare Side Effects

  • Corneal ulceration.
  • Severe allergic reaction, including anaphylaxis.
  • Vision loss.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Toxic keratitis.

Precautions & Warnings

Use chloramphenicol eye drops only as directed and consider the following precautions.

  • Hypersensitivity: avoid in patients with known allergy to chloramphenicol or other amphenicols.
  • Severe ocular surface damage: do not use on compromised corneas without specialist advice.
  • Duration of therapy: limit to the prescribed period to reduce resistance risk.
  • Monitor for allergic reactions: discontinue if severe irritation or systemic signs develop.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Chloramphenicol eye drops can interact with systemic and topical agents.

Major Interactions (Avoid)

  • Systemic aminoglycosides: may increase ototoxicity risk.
  • Systemic anticoagulants: potential enhancement of anticoagulant effect.
  • Systemic carbamazepine: heightened risk of bone‑marrow suppression.

Moderate Interactions (Monitor Closely)

  • Topical non‑steroidal anti‑inflammatory drugs: may increase ocular irritation.
  • Other topical antibiotics: possible antagonistic effects.
  • Systemic CYP450 inhibitors: could raise chloramphenicol plasma levels.

Frequently Asked Questions

Kloramfenikol Minims is a chloramphenicol‑based ophthalmic solution indicated for the treatment of bacterial conjunctivitis, ocular surface infections and for prophylaxis after eye surgery. It works by delivering a topical antibiotic directly to the eye to eliminate susceptible bacteria.

Chloramphenicol interferes with bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing peptide bond formation. This bacteriostatic action stops bacterial growth on the ocular surface, allowing the body's immune defenses to clear the infection.

The dosing regimen for Kloramfenikol Minims is determined by the prescribing eye‑care professional. Typical regimens involve one to two drops per affected eye, administered several times daily for a limited period, but the exact schedule should follow the prescriber’s instructions.

Safety data for chloramphenicol ophthalmic use in pregnancy and lactation are limited. The product should be used only if the potential benefit justifies any potential risk to the fetus or infant, and the decision should be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with fluoroquinolone eye drops, chloramphenicol offers a broad spectrum against Gram‑positive and some Gram‑negative organisms but has a lower risk of developing resistance. However, fluoroquinolones may be preferred for resistant strains, while chloramphenicol remains a cost‑effective option for many routine infections.

Store the ophthalmic solution at room temperature, below 25 °C, in its original container. Protect it from direct sunlight, moisture and extreme temperatures. Keep the bottle tightly closed when not in use to maintain sterility.

The solution is applied topically as eye drops. The patient should wash hands, tilt the head back, pull down the lower eyelid, and instill the prescribed number of drops into the conjunctival sac. Avoid touching the dropper tip to any surface.

Serious risks include corneal ulceration, severe allergic reactions such as anaphylaxis, and rare systemic effects like bone‑marrow suppression if absorbed in significant amounts. Immediate medical attention is required if vision changes, severe pain or systemic symptoms occur.

Patients with a known hypersensitivity to chloramphenicol or other amphenicols should avoid this product. It is also contraindicated in eyes with severe epithelial damage unless directed by a specialist, and it should not be used for prolonged periods without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.