Product image of Kloramfenikol Santen (Chloramphenicol) supplied by GNH India

Kloramfenikol Santen

Active Ingredient:
Chloramphenicol
Origin:
EU

Kloramfenikol Santen (Chloramphenicol)

Chloramphenicol, the active ingredient in Kloramfenikol Santen, is an antibiotic presented as an ophthalmic preparation for ocular use. It treats bacterial eye infections in patients requiring topical therapy.

GNH India supplies Kloramfenikol Santen as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Santen Oy

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Chloramphenicol is used to manage bacterial infections of the eye.

  • Conjunctivitis: reduces bacterial load and alleviates ocular inflammation.
  • Keratitis: treats corneal bacterial infection and promotes healing.
  • Blepharitis: controls bacterial overgrowth on eyelid margins and improves symptoms.

How It Works

  • Chloramphenicol inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing peptide chain elongation. This action halts bacterial growth and leads to bacteriostatic effects in susceptible ocular pathogens.

Side Effects

Chloramphenicol may cause ocular and systemic adverse reactions.

Common Side Effects

  • Eye irritation or burning sensation.
  • Redness of the conjunctiva.
  • Excessive tearing.
  • Foreign body sensation.
  • Blurred vision.
  • Mild localized allergic reaction.

Serious or Rare Side Effects

  • Aplastic anemia or bone‑marrow suppression.
  • Severe allergic reactions including anaphylaxis.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Visual loss unrelated to infection.
  • Systemic toxicity from prolonged absorption.
  • Severe dermatitis.

Precautions & Warnings

When using chloramphenicol eye drops, consider the following precautions.

  • Avoid use in patients with known hypersensitivity to chloramphenicol: discontinue immediately if reaction occurs.
  • Do not use for viral or fungal eye infections: confirm bacterial etiology before treatment.
  • Limit duration of therapy: follow prescriber guidance to reduce resistance risk.
  • Monitor for systemic absorption signs in prolonged use: report unusual fatigue or bruising.
  • Store at below 25°C: keep in original container, protect from moisture and light.

Avoid Interactions

Chloramphenicol can interact with certain systemic medications and ocular agents.

Major Interactions (Avoid)

  • Systemic aminoglycosides: may increase ototoxicity.
  • Oral anticoagulants (e.g., warfarin): potential enhancement of anticoagulant effect.
  • Oral contraceptives: possible reduction of contraceptive efficacy.

Moderate Interactions (Monitor Closely)

  • Concurrent topical antibiotics: risk of additive ocular toxicity.
  • Non‑steroidal anti‑inflammatory eye drops: may increase irritation.
  • Drugs metabolized by CYP2C9 (e.g., certain NSAIDs): chloramphenicol may alter plasma levels.

Frequently Asked Questions

Kloramfenikol Santen is a chloramphenicol‑based ophthalmic preparation indicated for the treatment of bacterial eye infections such as conjunctivitis, keratitis and blepharitis. It is applied topically to the eye to reduce bacterial load and promote healing.

Chloramphenicol interferes with bacterial protein synthesis by binding to the 50S subunit of the ribosome. This blocks peptide chain formation, halting bacterial growth and providing a bacteriostatic effect against susceptible ocular pathogens.

The dosing regimen for Kloramfenikol Santen is determined by the prescribing clinician based on the type and severity of the infection, patient age and response to therapy. The prescriber will specify the number of drops, frequency and duration of treatment.

Safety data for chloramphenicol eye drops in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified health professional.

To place an order, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Chloramphenicol offers broad‑spectrum activity against many Gram‑positive and Gram‑negative bacteria and is often used when resistance to fluoroquinolones or macrolides is a concern. Unlike some newer agents, it is bacteriostatic rather than bactericidal and may have a different safety profile, particularly regarding rare systemic toxicity.

Store the product at temperatures below 25 °C, in its original container, protected from moisture and direct light. Do not freeze. Keep out of reach of children and avoid exposure to excessive heat or humidity.

The eye drops are applied directly to the affected eye(s) as directed by the prescriber, typically by pulling down the lower eyelid and instilling the prescribed number of drops. Hands should be washed before use, and the dropper tip should not touch the eye or any surface.

Serious adverse events include aplastic anemia, severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome and other severe skin reactions, as well as visual loss unrelated to infection. Any signs of systemic toxicity, unexplained bruising, or severe eye discomfort should prompt immediate medical evaluation.

Patients with a known hypersensitivity to chloramphenicol or any component of the formulation should avoid its use. It is also contraindicated for viral, fungal or non‑infectious inflammatory eye conditions, and should be used with caution in individuals with a history of bone‑marrow disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.