Product image of Kloramfenikol Santen (Chloramphenicol) supplied by GNH India

Kloramfenikol Santen

Active Ingredient:
Chloramphenicol
Origin:
EU

Kloramfenikol Santen (Chloramphenicol)

Chloramphenicol, the active ingredient in Kloramfenikol Santen, is an amphenicol presented as an ophthalmic solution for ocular use. It treats bacterial conjunctivitis and other ocular bacterial infections in patients of all ages.

GNH India supplies Kloramfenikol Santen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Santen Oy

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Chloramphenicol acts as a broad‑spectrum antibacterial for ocular surface infections.

  • Bacterial conjunctivitis: reduces bacterial load and relieves redness, discharge and irritation.
  • Post‑operative ocular infection: prevents or treats bacterial contamination after eye surgery.
  • Other ocular bacterial infections: effective against susceptible Gram‑positive and Gram‑negative organisms causing keratitis or blepharitis.

How It Works

  • Chloramphenicol inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, blocking peptide bond formation. This action halts bacterial growth and leads to a bacteriostatic effect against a wide range of Gram‑positive and Gram‑negative organisms that may colonize the ocular surface.

Side Effects

Adverse ocular reactions may occur with chloramphenicol eye drops.

Common Side Effects

  • Eye irritation or burning sensation.
  • Redness of the conjunctiva.
  • Itching or mild pruritus.
  • Temporary blurred vision.
  • Mild allergic conjunctivitis.
  • Stinging upon instillation.

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis) with swelling and systemic symptoms.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis involving the eye.
  • Toxic keratopathy or corneal ulceration.
  • Vision loss due to severe ocular inflammation.
  • Bone marrow suppression with systemic absorption (rare).

Precautions & Warnings

When using chloramphenicol ophthalmic solution, consider the following precautions.

  • Allergy: discontinue if hypersensitivity to chloramphenicol or any component is known.
  • Duration: limit treatment to the prescribed period to reduce resistance risk.
  • Contact lenses: avoid wearing lenses during therapy unless advised.
  • Systemic absorption: use caution in patients with pre‑existing bone‑marrow disorders.
  • Pregnancy and lactation: safety not established; avoid unless benefits outweigh risks.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Chloramphenicol eye drops may interact with other systemic or topical agents.

Major Interactions (Avoid)

  • Systemic chloramphenicol: concurrent use may increase systemic toxicity.
  • Live vaccines: may diminish vaccine efficacy due to immunosuppression.
  • Other ophthalmic antibiotics: potential antagonistic effects.

Moderate Interactions (Monitor Closely)

  • Topical non‑steroidal anti‑inflammatory drugs: may increase ocular irritation.
  • Anticoagulants: monitor for bleeding if systemic absorption occurs.
  • Alcohol: may potentiate bone‑marrow suppression in susceptible individuals.

Frequently Asked Questions

Kloramfenikol Santen is an ophthalmic solution containing chloramphenicol. It is used to treat bacterial infections of the eye, such as bacterial conjunctivitis, postoperative ocular infections, and other susceptible bacterial keratitis or blepharitis.

Chloramphenicol works by binding to the bacterial 50S ribosomal subunit, inhibiting protein synthesis. This stops bacterial growth, providing a bacteriostatic effect that helps clear the infection on the ocular surface.

The dosing regimen for Kloramfenikol Santen is determined by the prescribing clinician based on the type and severity of the infection, patient age, and response to therapy. The prescriber will specify the number of drops and frequency.

Safety of chloramphenicol eye drops in pregnancy and lactation has not been definitively established. Use is generally avoided unless the potential benefit justifies the potential risk, and the decision should be made by a healthcare professional.

To order, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Chloramphenicol offers broad‑spectrum coverage against many Gram‑positive and Gram‑negative bacteria and is often used when resistance to other agents is a concern. Compared with fluoroquinolone eye drops, it may have a lower risk of promoting resistance but requires careful monitoring for rare systemic toxicity.

Store the ophthalmic solution at ambient temperature, below 25 °C, in its original packaging. Protect it from direct light and moisture to maintain stability and potency.

The solution is applied directly to the affected eye(s) as drops, according to the prescriber’s instructions. Typically, the recommended number of drops is placed into the conjunctival sac, avoiding contact with the eyelid or lashes.

Serious risks include severe allergic reactions such as anaphylaxis, toxic keratopathy, Stevens‑Johnson syndrome, and, rarely, systemic bone‑marrow suppression if significant absorption occurs. Immediate medical attention is required if any of these symptoms develop.

Patients with a known hypersensitivity to chloramphenicol or any component of the formulation should avoid use. Caution is also advised for individuals with pre‑existing bone‑marrow disorders, and it is generally contraindicated in pregnancy unless clearly needed.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Chloramphenicol

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT