Kloramfenikol Santen (Chloramphenicol)

Chloramphenicol inhibits bacterial protein synthesis by binding to the 50S subunit of the bacterial ribosome. This blocks peptide bond formation, halting bacterial growth and leading to a bacteriostatic effect against a wide range of ocular pathogens.

The dosing regimen for Kloramfenikol Santen is determined by the prescribing clinician based on the specific infection, severity, and patient factors. Typical regimens involve one to two drops per eye several times daily for a limited period, but the exact schedule should follow the prescriber’s instructions.

Safety data for chloramphenicol ophthalmic use in pregnancy and lactation are limited. It is classified as a precautionary drug, and use should only be considered if the potential benefit outweighs any possible risk. Healthcare providers should evaluate each case individually.

To order Kloramfenikol Santen, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Chloramphenicol offers broad‑spectrum coverage against many Gram‑positive and Gram‑negative ocular bacteria and is often used when resistance to fluoroquinolones or macrolides is a concern. Unlike some newer agents, it is not associated with significant corneal toxicity but requires careful monitoring for rare systemic effects.

Kloramfenikol Santen should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from direct light and moisture, and discard any solution that appears discolored or contaminated.

The product is applied topically to the affected eye(s) as drops. The patient should wash their hands, tilt the head back, pull down the lower eyelid, and place the prescribed number of drops into the conjunctival sac. Avoid touching the tip of the bottle to the eye or any surface.

Serious risks, though rare, include allergic contact dermatitis, Stevens‑Johnson syndrome, toxic epidermal necrolysis, and systemic bone‑marrow suppression such as aplastic anemia. Immediate medical attention is required if severe skin reactions, unexplained bruising, or sudden vision changes occur.

Patients with a known hypersensitivity to chloramphenicol or any component of the formulation should avoid using Kloramfenikol Santen. It is also contraindicated in viral conjunctivitis, and caution is advised in pregnant or nursing women, infants, and individuals with compromised corneal integrity.