Product image of Klyx (Docusate Sodium, Sorbitol (E420)) supplied by GNH India

Klyx

Active Ingredient:
Docusate Sodium, Sorbitol (E420)
Origin:
EU

Klyx (Docusate Sodium, Sorbitol (E420))

Docusate sodium and sorbitol, the active ingredient in Klyx, is a stool softener and osmotic laxative presented as a rectal suppository for rectal use. It helps relieve occasional constipation in adult patients by softening stool and promoting easier evacuation, and may be used when dietary measures are insufficient.

GNH India supplies Klyx as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality, regulatory compliance, and reliable logistics for global distribution, with full traceability and support for regulatory filings.

Manufacturer / TM Owner

Ferring Läkemedel Ab

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Klyx, containing docusate sodium and sorbitol, is used to manage constipation, a disorder of reduced bowel motility, by softening stool and increasing intestinal water content.
  • Constipation: softens stool and facilitates easier passage in adults
  • Hard stool: increases water content to reduce stool hardness
  • Delayed bowel movements: promotes regularity by enhancing stool moisture
  • Occasional constipation after surgery: helps restore normal bowel function
  • Anal fissure prevention: reduces straining during defecation
  • Pregnancy‑related constipation: provides gentle stool softening when other measures fail

How It Works

  • Docusate sodium acts as a surfactant that lowers the surface tension of fecal material, allowing water and fatty acids to penetrate the stool matrix. Sorbitol, an osmotic agent, draws water into the intestinal lumen by osmosis, increasing stool hydration. The combined effect results in softer, bulkier stool that can be expelled more easily through the rectum. This dual action helps normalize bowel movements without stimulating intestinal muscle activity.

Side Effects

Klyx may cause adverse reactions, most of which are mild and transient.

Common Side Effects

  • Rectal irritation: mild burning or itching at the application site
  • Abdominal cramping: mild discomfort or spasms
  • Diarrhea: loose stools
  • Nausea: feeling of sickness
  • Flatulence: increased gas production

Serious or Rare Side Effects

  • Severe abdominal pain: intense pain requiring medical attention
  • Allergic reaction: rash, swelling, or difficulty breathing
  • Rectal bleeding: unexpected blood in stool
  • Electrolyte imbalance: abnormal potassium or sodium levels
  • Persistent diarrhea: prolonged watery stools leading to dehydration

Precautions & Warnings

  • Before using Klyx, consider the following precautions.
  • Assess hydration status: ensure patient is adequately hydrated before use
  • Avoid in bowel obstruction: contraindicated if mechanical blockage is present
  • Use cautiously in renal impairment: monitor fluid balance
  • Do not exceed recommended frequency: follow prescriber instructions
  • Pregnancy and breastfeeding: consult healthcare professional before use
  • Store at room temperature: keep in original packaging, protect from moisture and direct sunlight

Avoid Interactions

Klyx may interact with other medications; review the following.

Major Interactions (Avoid)

  • Concurrent use with mineral oil: risk of fat malabsorption and reduced efficacy
  • Combination with other sorbitol‑containing laxatives: may cause severe diarrhea
  • Use with high‑dose electrolyte supplements: potential for electrolyte disturbances

Moderate Interactions (Monitor Closely)

  • Anticholinergic agents: may diminish laxative effect
  • Opioid analgesics: can counteract stool softening
  • Diuretics: monitor electrolytes during combined use

Frequently Asked Questions

Klyx is an over‑the‑counter rectal formulation containing docusate sodium and sorbitol, indicated for the temporary relief of occasional constipation in adults. It works by softening stool and increasing intestinal water content, making bowel movements easier.

Docusate sodium is a surfactant that reduces the surface tension of fecal material, allowing water and fatty acids to penetrate the stool matrix. This increases stool moisture and softness, facilitating smoother passage through the rectum without stimulating intestinal muscle activity.

The appropriate dose of Klyx is determined by a qualified healthcare professional based on the patient’s condition, age, and response. The prescriber will specify the number of suppositories and frequency of administration, and patients should follow that guidance exactly.

Safety data for Klyx in pregnancy or lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before using the product to weigh potential benefits against any unknown risks.

To place an order, submit an enquiry on the Klyx product page at gnhindia.com, providing the required quantity and your institutional credentials. GNH India works with hospitals, pharmacies and procurement teams worldwide, then replies with pricing, availability, shipping details and any necessary import documentation.

Compared with stimulant laxatives, Klyx offers a gentler, stool‑softening approach that does not stimulate intestinal contractions, reducing the risk of cramping. It differs from bulk‑forming agents by directly increasing stool moisture, making it suitable for patients who need rapid relief without added fiber.

Klyx should be stored at room temperature, preferably below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keeping the product in a dry, cool environment helps maintain its stability and effectiveness.

Klyx is supplied as a rectal suppository. The patient should wash hands, lie on their side with the lower leg straightened, gently insert the suppository into the rectum, and remain lying down for a few minutes to allow it to melt and be absorbed.

Although rare, serious adverse events can include severe abdominal pain, rectal bleeding, allergic reactions such as rash or breathing difficulty, and electrolyte imbalance from prolonged diarrhea. Any of these symptoms require immediate medical attention.

Klyx is contraindicated in individuals with known hypersensitivity to docusate sodium or sorbitol, those with mechanical bowel obstruction, and patients with severe inflammatory bowel disease unless directed by a physician. It should also be used with caution in patients with renal impairment or electrolyte disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Docusate Sodium, Sorbitol (E420)

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT