Product image of Klyx (Docusate Sodium, Sorbitol (E420)) supplied by GNH India

Klyx

Active Ingredient:
Docusate Sodium, Sorbitol (E420)
Origin:
EU

Klyx (Docusate Sodium, Sorbitol (E420))

Docusate Sodium and Sorbitol, the active ingredients in Klyx, are a stool softener and osmotic laxative presented as a suppository for rectal use. They treat constipation in adults by softening stool and drawing water into the intestinal lumen.
GNH India supplies Klyx as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ferring Lægemidler A/S

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Indications & Clinical Uses

Klyx, a stool softener and osmotic laxative, is indicated for the management of constipation.

  • Constipation: softens stool and promotes bowel movement in patients with functional constipation.
  • Occasional constipation: provides short‑term relief for intermittent constipation episodes.
  • Post‑operative constipation: aids in restoring regular bowel movements after surgical procedures.

How It Works

  • Docusate sodium acts as a surfactant that lowers surface tension, allowing water and fat to penetrate the stool and soften it. Sorbitol functions as an osmotic agent, drawing water into the intestinal lumen, increasing stool volume and stimulating peristalsis, thereby facilitating bowel evacuation.

Side Effects

Common Side Effects

  • Rectal irritation: mild burning or discomfort at the site of insertion.
  • Abdominal cramping: transient stomach cramps after use.
  • Diarrhea: loose stools occurring shortly after administration.
  • Nausea: occasional feeling of queasiness.
  • Flatulence: increased gas production.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Severe rectal bleeding: unexpected blood loss from the rectum.
  • Electrolyte imbalance: abnormal levels of sodium or potassium with prolonged use.

Precautions & Warnings

Before using Klyx, consider the following precautions.

  • Pregnancy: safety not established; consult a healthcare provider before use.
  • Breastfeeding: unknown safety; use only if benefits outweigh potential risks.
  • Rectal disorders: avoid if there is active rectal bleeding, ulceration, or severe hemorrhoids.
  • Concomitant laxatives: review use of other laxatives to prevent excessive bowel movements.
  • Hydration: maintain adequate fluid intake to support stool softening.
  • Store at room temperature: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Klyx may interact with other medications as follows.

Major Interactions (Avoid)

  • Other stimulant laxatives: increased risk of electrolyte disturbances.
  • Anticholinergic drugs: may reduce the laxative effect.
  • Mineral oil: can interfere with absorption of other oral medications.

Moderate Interactions (Monitor Closely)

  • Diuretics: monitor electrolyte levels during combined use.
  • Magnesium‑containing antacids: may enhance the laxative effect.
  • Opioid analgesics: may diminish efficacy of Klyx in relieving constipation.

Frequently Asked Questions

Klyx is an over‑the‑counter rectal suppository containing docusate sodium and sorbitol. It is used to relieve constipation by softening stool and drawing water into the intestine, facilitating easier bowel movements.

Docusate sodium acts as a surfactant, reducing surface tension of the stool so that water and fatty substances can penetrate, which softens the stool and makes it easier to pass.

The appropriate dose of Klyx is determined by the prescribing healthcare professional based on the patient’s condition, age, and response. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Safety of Klyx in pregnancy and breastfeeding has not been established. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their healthcare provider before using this product.

To order Klyx, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Klyx combines a stool‑softening agent (docusate sodium) with an osmotic agent (sorbitol), offering a dual mechanism that can be gentler than stimulant laxatives. It is typically preferred for mild to moderate constipation when a rapid, harsh effect is not required.

Klyx should be stored at room temperature, kept in its original packaging, and protected from moisture and excessive heat to maintain its stability and effectiveness.

Klyx is administered rectally as a suppository. The patient should lie on one side, insert the suppository gently into the rectum, and remain lying down for a few minutes to allow it to melt and take effect.

Serious risks, though rare, include severe allergic reactions such as rash, swelling or breathing difficulty, significant rectal bleeding, and electrolyte imbalances with prolonged or excessive use.

Klyx should be avoided by individuals with known hypersensitivity to docusate sodium, sorbitol, or any excipients, as well as patients with active rectal bleeding, severe hemorrhoids, or inflammatory bowel disease without medical advice.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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