Kochsalz Mit Glucose B. Braun Melsungen (Sodium Chloride, Glucose Monohydrate)

Kochsalz Mit Glucose is used in clinical situations that require rapid restoration of intravascular volume, electrolyte balance, or blood glucose.

• Fluid replacement: restores extracellular fluid volume after dehydration or blood loss.
• Electrolyte balance: corrects sodium deficits and maintains osmotic equilibrium.
• Hypoglycemia treatment: supplies glucose to raise blood sugar in acute low‑glucose states.
• Parenteral nutrition support: provides both electrolytes and an energy source as part of total nutrient admixtures.

• The solution delivers sodium chloride, which expands extracellular fluid and stabilises osmotic pressure, while glucose monohydrate enters cells via facilitated transport and serves as an immediate metabolic substrate. Together they increase intravascular volume, correct hyponatremia, and prevent or treat hypoglycaemia by supplying readily utilizable carbohydrate.

Adverse reactions may occur with any intravenous solution. Monitoring during infusion is recommended.

Common Side Effects

• Phlebitis or irritation at the infusion site.
• Mild hypernatremia if large volumes are administered rapidly.
• Transient hyperglycaemia, especially in diabetic patients.
• Electrolyte imbalance such as hyperchloremia.
• Allergic skin rash or urticaria.
• Localized swelling or edema.

Serious or Rare Side Effects

• Severe hypernatremia leading to neurological symptoms.
• Acute pulmonary oedema from rapid volume overload.
• Anaphylactic reaction requiring emergency intervention.
• Metabolic acidosis due to chloride load.
• Infection related to catheter use.
• Hemolysis in patients with glucose‑6‑phosphate dehydrogenase deficiency.

Use the solution only under medical supervision and according to prescribed infusion rates.

• Patient assessment: evaluate fluid status, electrolyte levels and blood glucose before initiation.
• Infusion rate: avoid rapid bolus administration unless specifically indicated.
• Compatibility: verify compatibility with other IV drugs before co‑administration.
• Monitoring: observe vital signs, serum electrolytes and glucose during therapy.
• Special populations: adjust dosing in renal or cardiac failure, and in neonates.
• Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Certain drugs may alter the safety or efficacy of the solution.

Major Interactions (Avoid)

• Concurrent administration of hypertonic glucose solutions: risk of severe hyperglycaemia.
• High‑dose sodium‑containing medications (e.g., hypertonic saline): may cause dangerous sodium overload.
• Certain antibiotics that precipitate with chloride (e.g., ceftriaxone) when mixed in the same line.

Moderate Interactions (Monitor Closely)

• Loop diuretics: may enhance electrolyte shifts, requiring closer monitoring.
• ACE inhibitors or ARBs: can potentiate hypotension when large volumes are infused.
• Insulin therapy: glucose content may affect insulin dosing requirements.
• Beta‑blockers: may mask tachycardia that signals fluid overload.
• Anticoagulants: volume expansion can influence haemodilution and affect coagulation parameters.