Product image of Kohle-Tabletten (Charcoal, Activated) supplied by GNH India

Kohle-Tabletten

Active Ingredient:
Charcoal, Activated
Origin:
EU

Kohle-Tabletten (Charcoal, Activated)

Activated charcoal, the active ingredient in Kohle-Tabletten, is an intestinal adsorbent presented as a tablet for oral use. It treats acute oral poisoning, drug overdose, and reduction of intestinal gas in adults and children as directed by a healthcare professional.

GNH India supplies Kohle-Tabletten as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Cheplapharm Arzneimittel Gmbh

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Indications & Clinical Uses

Activated charcoal is used as an intestinal adsorbent for gastrointestinal decontamination.

  • Acute oral poisoning: binds ingested toxins and limits systemic absorption.
  • Drug overdose: adsorbs excess medication in the gut to reduce toxicity.
  • Intestinal gas: reduces bloating by binding gas‑producing substances.

How It Works

  • Activated charcoal consists of a porous carbon matrix with a large surface area that physically adsorbs a wide range of organic molecules, toxins, and gases in the gastrointestinal tract. By binding these substances, it prevents their passage across the intestinal mucosa, thereby lowering systemic exposure and facilitating elimination via feces.

Side Effects

Activated charcoal may cause several adverse reactions, most of which are mild and transient.

Common Side Effects

  • Constipation: reduced bowel movements may occur.
  • Black stools: discoloration due to charcoal passage.
  • Nausea or vomiting: gastrointestinal irritation.
  • Abdominal discomfort: mild cramping or bloating.
  • Flatulence: excess gas production.
  • Taste alteration: temporary metallic taste.

Serious or Rare Side Effects

  • Aspiration: risk if vomited and inhaled, leading to respiratory complications.
  • Allergic reactions: rash, itching, or urticaria indicating hypersensitivity.
  • Severe constipation or bowel obstruction: may require medical intervention.
  • Electrolyte imbalance: rare but possible with prolonged use.
  • Gastrointestinal hemorrhage: uncommon but serious bleeding event.

Precautions & Warnings

When using Kohle-Tabletten, consider the following safety measures.

  • Dosage adjustment: modify dose in patients with reduced gastrointestinal motility.
  • Medical supervision: required for children, pregnant or breastfeeding women.
  • Avoid concurrent use: do not take with oral medications that require absorption unless spaced appropriately.
  • Hydration: maintain adequate fluid intake to prevent constipation.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Activated charcoal can affect the absorption of several concomitant agents.

Major Interactions (Avoid)

  • Antacids: may reduce charcoal's adsorption capacity.
  • Oral medications: charcoal can bind many drugs, decreasing their effectiveness.
  • Iron supplements: adsorption may impair iron absorption.

Moderate Interactions (Monitor Closely)

  • Warfarin: monitor INR as charcoal may affect anticoagulant levels.
  • Lithium: observe serum lithium concentrations.
  • Phenobarbital: may require dose adjustment due to reduced absorption.

Frequently Asked Questions

Kohle-Tabletten contain activated charcoal and are used as an intestinal adsorbent for gastrointestinal decontamination. They are indicated for acute oral poisoning, drug overdose, and the reduction of intestinal gas, helping to bind toxins or gas‑producing substances in the gut.

Activated charcoal works by providing a highly porous carbon surface that physically adsorbs a broad spectrum of organic molecules, toxins, and gases within the gastrointestinal tract. This adsorption prevents the substances from being absorbed into the bloodstream, allowing them to be eliminated in the feces.

The dose of Kohle-Tabletten is determined by the prescribing healthcare professional based on factors such as the patient’s age, weight, the severity of the poisoning or overdose, and the time elapsed since ingestion. No fixed regimen is provided here; the prescriber sets the appropriate amount.

Safety data for activated charcoal in pregnancy and lactation are limited. It should only be used when the potential benefit outweighs any possible risk to the fetus or infant, and only under medical supervision.

To order Kohle-Tabletten, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Compared with other decontamination agents such as sodium sulfate or sorbitol, activated charcoal offers broad‑spectrum adsorption of many toxins and drugs but does not enhance gastric emptying. It is generally well‑tolerated, though it may interfere with the absorption of concomitant oral medications, a consideration less prominent with some alternative agents.

Kohle-Tabletten should be stored at ambient temperature, below 25 °C, in their original packaging. Protect them from moisture, direct sunlight, and excessive heat to maintain product integrity.

Kohle-Tabletten are taken orally with a sufficient amount of water. They are usually administered as soon as possible after ingestion of a toxin or drug, following the dosage instructions provided by a healthcare professional.

Serious risks include aspiration if the tablet is vomited and inhaled, severe constipation or bowel obstruction, allergic reactions such as rash or urticaria, and rare cases of gastrointestinal hemorrhage. Prompt medical attention is required if any of these occur.

Kohle-Tabletten should be avoided in patients with known gastrointestinal obstruction, perforation, or severe motility disorders, as well as in individuals with a documented hypersensitivity to activated charcoal. Use in these situations may exacerbate the underlying condition.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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