Product image of Kontracept (Ethinylestradiol, Gestodene) supplied by GNH India

Kontracept

Active Ingredient:
Ethinylestradiol, Gestodene
Origin:
EU

Kontracept (Ethinylestradiol, Gestodene)

Ethinylestradiol and Gestodene, the active ingredients in Kontracept, are a combined estrogen‑progestogen presented as a tablet for oral use. They prevent pregnancy in women of childbearing age.

GNH India supplies Kontracept as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Adamed Pharma S.A.

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Indications & Clinical Uses

Kontracept, a combined estrogen‑progestogen oral contraceptive, is indicated for hormonal contraception.

  • Prevention of pregnancy: provides reliable contraceptive protection for women of reproductive potential.
  • Regulation of menstrual cycle: helps achieve more regular bleeding patterns and reduces menstrual discomfort.
  • Treatment of acne: can improve mild to moderate acne associated with hormonal fluctuations.

How It Works

  • Kontracept works by delivering ethinylestradiol and gestodene, which bind to estrogen and progesterone receptors respectively. The estrogen component suppresses the mid‑cycle luteinizing hormone surge, preventing ovulation, while the progestogen thickens cervical mucus and alters the endometrial lining, creating an environment hostile to fertilisation and implantation.

Side Effects

Common Side Effects

  • Nausea or mild gastrointestinal upset.
  • Breast tenderness or enlargement.
  • Headache or migraine.
  • Spotting or breakthrough bleeding.
  • Weight gain or fluid retention.
  • Mood changes or irritability.

Serious or Rare Side Effects

  • Venous thromboembolism (deep‑vein thrombosis, pulmonary embolism).
  • Arterial thrombosis (stroke, myocardial infarction).
  • Severe hypertension.
  • Hepatic adenoma or other liver tumours.
  • Anaphylactic or severe allergic reactions.

Precautions & Warnings

Kontracept should be used only after a thorough medical assessment.

  • Contraindications: known thromboembolic disease, pregnancy, estrogen‑dependent tumours, severe liver dysfunction.
  • Smoking: avoid use in women over 35 who smoke due to increased cardiovascular risk.
  • Cardiovascular risk: assess blood pressure and lipid profile before initiation.
  • Drug interactions: review concomitant medications that may alter hormone levels.
  • Monitoring: schedule periodic evaluation of blood pressure and any signs of thrombosis.
  • Store at ambient temperature: keep tablets below 25 °C in the original container, protected from moisture and light.

Avoid Interactions

Kontracept may interact with several medicines that affect hormone metabolism.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin) can markedly reduce contraceptive efficacy.
  • Anticoagulants (e.g., warfarin) may have altered anticoagulant effect, requiring closer INR monitoring.
  • Certain antiretrovirals (e.g., efavirenz) can diminish hormone levels and increase pregnancy risk.

Moderate Interactions (Monitor Closely)

  • SSRIs and other antidepressants may increase bleeding tendency.
  • Azole antifungals (e.g., ketoconazole) can raise plasma hormone concentrations, potentially increasing side‑effect risk.
  • Herbal supplements such as St. John’s wort may lower contraceptive effectiveness.
  • Antibiotics (e.g., clarithromycin) may modestly affect hormone levels.
  • Anticonvulsants with moderate enzyme induction (e.g., phenobarbital) require monitoring of contraceptive reliability.

Frequently Asked Questions

Kontracept is a prescription oral tablet that combines ethinylestradiol and gestodene to provide hormonal contraception. It is used to prevent pregnancy in women of reproductive age and may also help regulate menstrual cycles and improve hormone‑related acne.

Ethinylestradiol suppresses the mid‑cycle luteinising hormone surge, preventing ovulation, while gestodene thickens cervical mucus and alters the endometrial lining. Together they create conditions that block fertilisation and implantation.

The dosing regimen for Kontracept is determined by the prescribing clinician based on the product’s label and the patient’s individual needs. Patients should follow the prescriber’s instructions and not alter the schedule without medical advice.

Kontracept is contraindicated during pregnancy and should not be started in women who are already pregnant. Safety during breastfeeding has not been established; clinicians usually advise alternative contraception for nursing mothers.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Kontracept contains ethinylestradiol and gestodene, a low‑dose estrogen‑progestogen combination similar to many other COCs. Compared with products using higher‑dose estrogen or different progestogens, it may offer a favorable balance of efficacy and tolerability, but individual response varies and should be assessed by a healthcare professional.

Kontracept tablets should be stored at ambient temperature, below 25 °C, in the original blister pack or container. Protect them from moisture, heat and direct sunlight to maintain potency throughout the shelf‑life.

Kontracept is taken orally, usually once daily at the same time each day, as directed by the prescriber. The tablet is swallowed whole with water and should not be chewed or split unless specifically instructed.

The most serious risks include venous and arterial thromboembolic events such as deep‑vein thrombosis, pulmonary embolism, stroke, and myocardial infarction. Other rare but severe concerns are severe hypertension, hepatic tumours, and life‑threatening allergic reactions. Patients should seek immediate medical attention if they experience symptoms suggestive of these conditions.

Kontracept is contraindicated in women with a history of thromboembolic disorders, known or suspected pregnancy, estrogen‑dependent tumours, uncontrolled hypertension, severe liver disease, or those who smoke and are over 35 years old. A thorough medical evaluation is required before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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