Product image of Kopaq (Iohexol) supplied by GNH India

Kopaq

Active Ingredient:
Iohexol
Origin:
EU

Kopaq (Iohexol)

Iohexol, the active ingredient in Kopaq, is an iodinated contrast agent presented as an injectable solution for intraarterial, intrathecal, and intravenous use. It enhances radiographic contrast in patients undergoing angiography, computed tomography, myelography and other diagnostic imaging procedures.
GNH India supplies Kopaq as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Onko Pharmaceuticals Ltd.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Kopaq (iohexol) is an iodinated contrast agent used in radiographic imaging procedures.

  • Angiography: Improves vessel visualization by increasing X‑ray attenuation.
  • Computed tomography (CT) imaging: Enhances tissue contrast for better diagnostic detail.
  • Myelography: Provides clear delineation of spinal structures during contrast studies.
  • Other diagnostic imaging procedures requiring contrast: Facilitates visualization of anatomical structures.

How It Works

  • Iohexol is a non‑ionic, water‑soluble iodine‑based compound. After intra‑arterial, intravenous or intrathecal administration, its high‑density iodine atoms absorb X‑ray photons, increasing attenuation of the X‑ray beam in the vascular or cerebrospinal spaces. This creates a marked difference in radiodensity between contrast‑filled structures and surrounding tissues, thereby enhancing image contrast for radiographic, CT and myelographic studies.

Side Effects

Adverse reactions may occur following administration of iohexol.

Common Side Effects

  • Warm sensation at injection site: transient feeling of heat or flushing.
  • Nausea: mild to moderate upset stomach.
  • Metallic taste: temporary alteration of taste perception.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe allergic response requiring immediate medical attention.
  • Contrast‑induced nephropathy: acute kidney injury in susceptible patients.
  • Cardiac arrhythmia: irregular heart rhythm potentially triggered by rapid injection.

Precautions & Warnings

Prior to using Kopaq, consider the following precautions.

  • Assess renal function: evaluate serum creatinine before administration.
  • Screen for iodine allergy: obtain a detailed allergy history.
  • Use lowest effective dose: limit volume to the amount necessary for imaging.
  • Monitor vital signs: observe for hypotension or arrhythmia during injection.
  • Avoid rapid injection in high‑risk patients: inject slowly as recommended.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Iohexol may interact with other medications or agents.

Major Interactions (Avoid)

  • Concurrent nephrotoxic drugs: may increase risk of renal injury.
  • High‑dose iodinated contrast within 24 h: cumulative iodine load.
  • Radioactive iodine therapy: interference with iodine uptake.

Moderate Interactions (Monitor Closely)

  • Diuretics: may affect renal clearance of contrast.
  • Beta‑blockers: may mask hypotensive response.
  • ACE inhibitors: potential additive effect on renal function.

Frequently Asked Questions

Kopaq contains iohexol, an iodinated contrast medium used to improve the visibility of blood vessels, organs, and tissues during diagnostic imaging procedures such as angiography, computed tomography (CT) scans, and myelography. It helps radiologists obtain clearer images for accurate diagnosis.

Iohexol is a non‑ionic, iodine‑rich compound. When injected, its high‑density iodine atoms absorb X‑ray photons, increasing the attenuation of the X‑ray beam in the area where it circulates. This creates a contrast between the enhanced structures and surrounding tissues, allowing better image definition.

The dose of Kopaq is determined by the prescribing physician based on the specific imaging study, patient size, renal function, and the route of administration. Healthcare professionals calculate the appropriate volume and concentration required for each procedure.

Safety of iohexol in pregnancy or while breastfeeding has not been fully established. It should only be used if the potential diagnostic benefit outweighs any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To order Kopaq, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Kopaq (iohexol) is a non‑ionic, low‑osmolality contrast medium, offering a favorable safety profile compared with older high‑osmolality agents. Compared with other non‑ionic agents such as iopamidol, iohexol provides similar image quality and is often chosen based on availability, cost, and specific institutional preferences.

Kopaq should be stored at room temperature, below 25 °C, in its original packaging. Protect the solution from direct light and moisture. Do not freeze. Before use, inspect the vial for particulate matter or discoloration and handle with aseptic technique.

Kopaq is administered by a qualified healthcare professional via intra‑arterial, intravenous, or intrathecal injection, depending on the imaging study. The injection rate and volume are controlled to achieve optimal contrast enhancement while minimizing adverse reactions.

The most serious risks include severe allergic reactions (anaphylaxis), contrast‑induced nephropathy leading to acute kidney injury, and cardiac arrhythmias that may occur with rapid injection. Immediate medical attention is required if any of these events are suspected.

Kopaq should be avoided in patients with a known hypersensitivity to iodine‑based contrast media, severe renal impairment, uncontrolled hyperthyroidism, or those who have experienced severe reactions to previous contrast agents. The prescribing clinician must assess each patient’s suitability before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.