Korylan (Paracetamol, Codeine Phosphate Hemihydrate)

Paracetamol reduces pain and fever by centrally inhibiting cyclo‑oxygenase enzymes, lowering prostaglandin production. Codeine phosphate hemihydrate is converted in the liver to morphine, which activates μ‑opioid receptors in the brain and spinal cord, providing additional analgesia and a mild cough‑suppressant effect.

The specific dose of Korylan is determined by the prescribing clinician based on the individual’s age, weight, pain severity, and overall health status. Healthcare professionals follow local prescribing guidelines and adjust the regimen as needed for safety and efficacy.

Safety of Korylan in pregnancy and lactation has not been definitively established. Paracetamol is generally considered low‑risk, but codeine may pose risks to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential benefits and risks with their healthcare provider.

To order Korylan, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements if applicable) and necessary import documentation.

Compared with non‑opioid analgesics such as ibuprofen, Korylan adds an opioid component that can provide stronger pain relief for moderate pain but carries a higher risk of dependence and respiratory depression. Pure codeine products lack the antipyretic benefit of paracetamol. The choice depends on pain intensity, patient comorbidities, and risk‑benefit assessment by the prescriber.

Korylan tablets should be stored at room temperature, below 25 °C, in the original container to protect them from moisture and light. Keep the product out of reach of children and do not use after the expiry date printed on the packaging.

Korylan is taken orally, usually with a full glass of water. The tablet should be swallowed whole and not chewed or crushed, unless a healthcare professional advises otherwise. It is typically taken with or without food, as directed by the prescriber.

The most serious risks include respiratory depression, especially in patients with compromised breathing, severe allergic reactions (anaphylaxis), hepatic injury from paracetamol overdose, and the potential for dependence, abuse, or addiction related to the codeine component. Prompt medical attention is required if any of these symptoms appear.

Korylan should be avoided in individuals with known hypersensitivity to paracetamol, codeine, or any excipients, in patients with severe respiratory depression, uncontrolled asthma, or acute head injury. It is also contraindicated in children under 12 years of age and in patients taking monoamine oxidase inhibitors within two weeks of therapy.