Product image of Kostival (Preparation Of Symphytum X Uplandicum Herb (Der 0.5-0.7:1), Composed Of 40 % Liquid Extract From Sym) supplied by GNH India

Kostival

Active Ingredient:
Preparation Of Symphytum X Uplandicum Herb (Der 0.5-0.7:1), Composed Of 40 % Liquid Extract From Sym
Origin:
EU

Kostival (Preparation Of Symphytum X Uplandicum Herb (Der 0.5-0.7:1), Composed Of 40 % Liquid Extract From Sym)

Symphytum x uplandicum herb preparation, the active ingredient in Kostival, is a herbal botanical presented as a topical preparation for cutaneous use. It is traditionally applied to support skin health and aid the management of minor skin irritations, bruises and superficial burns in adults.
GNH India supplies Kostival as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Dr. Theiss Naturwaren Gmbh

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Indications & Clinical Uses

Kostival is a topical herbal preparation used for conditions affecting the skin and superficial tissues.

  • Minor skin abrasions: helps support the natural healing process and reduces discomfort.
  • Bruises and contusions: may lessen discoloration and soreness associated with superficial trauma.
  • Superficial burns: provides a soothing effect and assists in skin recovery.

How It Works

  • The preparation contains a 40 % liquid extract of Symphytum x uplandicum, which is rich in allantoin, rosmarinic acid and phenolic compounds. These constituents promote cellular proliferation, enhance collagen synthesis and exhibit anti‑inflammatory activity, thereby supporting tissue repair and reducing local inflammation when applied to the skin.

Side Effects

Kostival is generally well tolerated when used as directed, but skin reactions can occur.

Common Side Effects

  • Mild redness at the application site: transient irritation that resolves spontaneously.
  • Itching: occasional pruritus that subsides after discontinuation.
  • Dryness or flaking: mild desquamation of the treated area.

Serious or Rare Side Effects

  • Contact dermatitis: allergic reaction requiring cessation of use and medical evaluation.
  • Photosensitivity: increased skin sensitivity to sunlight, necessitating protection from UV exposure.
  • Systemic toxicity: unlikely but possible if large amounts are absorbed through broken skin, especially due to pyrrolizidine alkaloids.

Precautions & Warnings

Before using Kostival, consider the following safety measures.

  • Pregnancy: avoid use because of potential pyrrolizidine alkaloid exposure.
  • Breastfeeding: do not apply to nursing mothers to prevent transfer to infant.
  • Open wounds: do not apply on broken or ulcerated skin to limit systemic absorption.
  • Children under 12 years: avoid use unless specifically directed by a healthcare professional.
  • Allergy: discontinue immediately if signs of skin irritation or allergic reaction appear.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Kostival may interact with other topical agents or systemic medications.

Major Interactions (Avoid)

  • Concurrent use with other herbal preparations containing pyrrolizidine alkaloids: risk of cumulative toxicity.
  • Application together with potent topical corticosteroids on the same area: may mask irritation and delay detection of adverse reactions.

Moderate Interactions (Monitor Closely)

  • Systemic drugs metabolized by hepatic CYP450 enzymes: potential alteration of herbal component metabolism.
  • Phototoxic agents (e.g., certain antibiotics or retinoids): increased risk of skin photosensitivity.
  • Anticoagulant therapy: monitor for exaggerated bruising when used on contused skin.

Frequently Asked Questions

Kostival is a cutaneous herbal preparation containing Symphytum x uplandicum extract. It is applied to the skin to support the healing of minor abrasions, bruises, contusions and superficial burns, helping to reduce discomfort and promote tissue repair.

The herb extract is rich in allantoin and phenolic compounds that stimulate cell proliferation, enhance collagen formation and provide anti‑inflammatory effects. These actions collectively aid the skin’s natural repair mechanisms when the product is applied locally.

The appropriate amount and frequency of Kostival are determined by the prescribing healthcare professional based on the specific skin condition, size of the area treated and patient characteristics. No fixed dosing regimen is provided in the product information.

Because the preparation contains pyrrolizidine alkaloids, which may pose a risk to the fetus or infant, Kostival is not recommended for use during pregnancy or while breastfeeding unless a qualified clinician explicitly advises otherwise.

To place an order, submit an enquiry on the Kostival product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Kostival is a botanical topical formulation, whereas many conventional skin‑healing products are synthetic or contain corticosteroids. The herbal extract offers a natural approach with anti‑inflammatory and cell‑regenerative properties, but it may have a slower onset of action compared with potent steroidal preparations.

Kostival should be stored at room temperature, ideally below 25 °C, in its original packaging. Keep the container tightly closed, protect it from direct sunlight, and avoid exposure to moisture to maintain product stability.

The product is intended for external use only. Apply a thin layer to clean, dry skin over the affected area, gently massaging it in until absorbed. Frequency of application is determined by the prescriber, typically 1–3 times daily.

The most serious concerns involve allergic reactions such as contact dermatitis and, rarely, systemic toxicity from pyrrolizidine alkaloids if applied to large broken skin areas. Users should discontinue use and seek medical advice if severe skin irritation or systemic symptoms develop.

Kostival should not be used by pregnant or breastfeeding women, children under 12 years of age, individuals with known allergy to comfrey or related plants, or anyone with open wounds, ulcerated skin or compromised skin integrity unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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