Product image of Kreon (Pancreas Powder) supplied by GNH India

Kreon

Active Ingredient:
Pancreas Powder
Origin:
EU

Kreon (Pancreas Powder)

Pancreatin, the active ingredient in Kreon, is a pancreatic enzyme replacement therapy presented as an enteric‑coated capsule for oral use. It supplies the digestive enzymes amylase, lipase and protease to patients with exocrine pancreatic insufficiency caused by cystic fibrosis, chronic pancreatitis, pancreatic cancer, or after pancreatic resection, helping to improve nutrient digestion.

GNH India supplies Kreon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company ensures quality, regulatory compliance and reliable logistics for global healthcare providers.

Manufacturer / TM Owner

Viatris Healthcare Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Kreon is indicated for conditions involving exocrine pancreatic insufficiency, where it supplements deficient digestive enzymes.

  • Cystic fibrosis: improves digestion and nutrient absorption by providing pancreatic enzymes.
  • Chronic pancreatitis: reduces steatorrhea and abdominal discomfort associated with malabsorption.
  • Pancreatic cancer: supports digestive function when tumor involvement impairs pancreatic secretion.
  • Post‑pancreatic resection: aids in the breakdown of fats, proteins and carbohydrates after surgical loss of pancreatic tissue.

How It Works

  • Pancreatin contains a blend of the pancreatic enzymes amylase, lipase and protease. The enteric coating protects the enzymes from gastric acid, allowing them to reach the duodenum intact. Once released, the enzymes hydrolyze carbohydrates, fats and proteins, compensating for the patient’s deficient endogenous pancreatic secretion and facilitating normal nutrient absorption. This enzymatic activity restores the digestive cascade and reduces fecal fat loss.

Side Effects

Kreon may cause adverse reactions related to its enzyme content or capsule formulation.

Common Side Effects

  • Abdominal discomfort: mild cramping or pain after meals
  • Flatulence: increased gas production and bloating
  • Oily or fatty stools: steatorrhea due to unabsorbed fat
  • Nausea: feeling of sickness without vomiting
  • Constipation: reduced bowel movements and hard stools
  • Diarrhea: loose, watery stools

Serious or Rare Side Effects

  • Allergic reactions: rash, urticaria or anaphylaxis requiring immediate care
  • Severe abdominal pain: intense pain that may indicate obstruction
  • Intestinal obstruction: blockage of the intestinal tract
  • Fecal incontinence: loss of control over bowel movements
  • Pancreatitis exacerbation: worsening of pancreatic inflammation

Precautions & Warnings

Before prescribing Kreon, healthcare professionals should consider the following precautions.

  • Assess enzyme deficiency: evaluate stool fat content and clinical symptoms before initiating therapy.
  • Adjust dose individually: titrate based on nutritional status, weight and response.
  • Monitor for hypersensitivity: watch for signs of allergic reaction, especially in patients with porcine protein sensitivity.
  • Use with meals and snacks: take capsules at the start of each main meal for optimal enzyme activation.
  • Avoid concomitant use of antacids containing aluminum or magnesium: they may reduce enzyme efficacy.
  • Store at below 25°C: keep in the original container, protect from moisture and heat.

Avoid Interactions

Kreon can interact with certain medicines, affecting either its efficacy or the partner drug’s action.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: may bind enzymes and lower digestive activity.
  • Orlistat: reduces fat absorption and can diminish the benefit of pancreatic enzymes.
  • High‑dose proton pump inhibitors: may alter capsule dissolution and enzyme release.

Moderate Interactions (Monitor Closely)

  • Warfarin: changes in vitamin K absorption could affect anticoagulation control.
  • Digoxin: altered intestinal absorption may modify serum levels.
  • Tetracycline antibiotics: may chelate with enzymes and reduce their activity.

Frequently Asked Questions

Kreon is a prescription pancreatic enzyme replacement that provides the digestive enzymes amylase, lipase and protease. It is used to treat exocrine pancreatic insufficiency, a condition in which the pancreas does not produce enough enzymes to properly digest food. Indications include cystic fibrosis, chronic pancreatitis, pancreatic cancer and patients who have had part of the pancreas removed.

Pancreatin contains a mixture of pancreatic enzymes that break down carbohydrates, fats and proteins. The enteric coating protects the enzymes from stomach acid, allowing them to be released in the duodenum where they act on ingested nutrients. By supplementing the body’s own enzyme production, pancreatin restores normal digestion and improves absorption of nutrients.

The dosage of Kreon is individualized. A physician determines the appropriate number of capsules based on the patient’s weight, dietary fat intake, severity of enzyme deficiency and clinical response. Dosing is typically expressed in lipase units per meal and is adjusted to achieve optimal stool consistency and nutritional status.

Safety data for Kreon in pregnancy and lactation are limited. Because the product contains porcine‑derived enzymes, it should be used only if the potential benefit outweighs any possible risk to the fetus or infant. The prescribing clinician must evaluate the individual situation and discuss it with the patient.

To order Kreon, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides a quotation, availability, shipping details (including any temperature requirements) and assistance with import documentation.

Kreon is a high‑potency pancreatin formulation with an enteric coating, similar to other pancreatic enzyme products such as Creon or Pancreaze. Compared with non‑coated preparations, Kreon’s coating improves enzyme delivery to the intestine and may provide more consistent symptom control. Choice of product often depends on physician preference, dosing convenience and patient tolerance.

Kreon capsules should be stored at temperatures below 25 °C in their original blister pack, protected from moisture and direct sunlight. Do not refrigerate or freeze the product. Keep the containers tightly closed and out of reach of children. If the capsules become damaged or discoloured, discard them.

Kreon is taken orally with each main meal and snack. The enteric‑coated capsules are swallowed whole with water; they should not be crushed, chewed or opened, as this would destroy the protective coating and reduce efficacy. The dose may be adjusted according to the fat content of the meal and the patient’s clinical response.

Serious adverse events, although rare, include severe allergic reactions such as anaphylaxis, intestinal obstruction, and exacerbation of pancreatitis. Patients should be instructed to seek immediate medical attention if they develop rash, swelling, difficulty breathing, intense abdominal pain or signs of bowel blockage. Prompt reporting of these events allows timely management.

Kreon is contraindicated in individuals with a known hypersensitivity to porcine proteins or any component of the formulation. It should also be avoided in patients with active intestinal obstruction or severe gastrointestinal disease where enzyme therapy would not be effective. Clinicians must review the patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.