Product image of Kruidvat Antischimmel (Terbinafine Hydrochloride) supplied by GNH India

Kruidvat Antischimmel

Active Ingredient:
Terbinafine Hydrochloride
Origin:
EU

Kruidvat Antischimmel (Terbinafine Hydrochloride)

Terbinafine, the active ingredient in Kruidvat Antischimmel, is an allylamine antifungal presented as a topical formulation for topical use. It treats dermatophyte skin infections and nail fungus in patients with superficial fungal conditions.

GNH India supplies Kruidvat Antischimmel as a licensed, GDP-compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Healthypharm B.V.

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Indications & Clinical Uses

Terbinafine is an allylamine antifungal used to treat superficial fungal infections of the skin and nails.

  • Athlete's foot (tinea pedis): reduces itching and clears the infection on the feet.
  • Ringworm (tinea corporis): eliminates the fungal lesions on the body.
  • Nail fungus (onychomycosis): improves nail appearance and eradicates the causative fungus.

How It Works

  • Terbinafine inhibits the fungal enzyme squalene epoxidase, which blocks the conversion of squalene to ergosterol. This disruption prevents the synthesis of ergosterol, an essential component of fungal cell membranes, leading to accumulation of toxic squalene and ultimately causing fungal cell death.

Side Effects

Terbinafine may cause local and systemic reactions, most of which are mild and reversible.

Common Side Effects

  • Skin irritation at the application site: redness, burning, or itching.
  • Pruritus: mild itching around the treated area.
  • Dryness: localized skin dryness or flaking.
  • Erythema: mild redness of the skin.

Serious or Rare Side Effects

  • Allergic reaction: swelling, hives, or difficulty breathing.
  • Contact dermatitis: severe rash or blistering.
  • Hepatotoxicity: abnormal liver function tests (rare with topical use).
  • Stevens‑Johnson syndrome: severe skin detachment (extremely rare).

Precautions & Warnings

Before using Kruidvat Antischimmel, consider the following precautions.

  • Pregnancy: safety not established; consult a healthcare professional before use.
  • Breastfeeding: unknown safety; discuss with a physician.
  • Pre‑existing skin conditions: avoid use on damaged or inflamed skin.
  • Concomitant topical agents: do not apply other medicated creams to the same area.
  • Allergies: discontinue if signs of an allergic reaction appear.
  • Store at ambient temperature: keep in the original packaging, protect from moisture and excessive heat.

Avoid Interactions

Terbinafine topical has limited systemic absorption, but interactions may still occur.

Major Interactions (Avoid)

  • Concurrent use of other topical antifungals containing azoles: may increase local irritation.
  • Application over large areas combined with systemic terbinafine: risk of systemic exposure.

Moderate Interactions (Monitor Closely)

  • Use with corticosteroid creams: may mask signs of infection.
  • Use with occlusive dressings: can enhance absorption and irritation.
  • Use on compromised skin barrier: may increase systemic absorption.

Frequently Asked Questions

Kruidvat Antischimmel contains terbinafine and is indicated for the topical treatment of superficial fungal infections such as athlete's foot (tinea pedis), ringworm (tinea corporis) and nail fungus (onychomycosis). It works by targeting the fungus directly on the skin or nail surface.

Terbinafine inhibits the fungal enzyme squalene epoxidase, which blocks the synthesis of ergosterol, a vital component of fungal cell membranes. Without ergosterol, the fungal cell membrane becomes unstable, leading to accumulation of squalene and ultimately causing fungal cell death.

The specific dose and duration are determined by the prescribing healthcare professional based on the infection type, severity, and patient factors. Patients should follow the instructions provided by their clinician or the product label.

Safety data for terbinafine topical use in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Terbinafine belongs to the allylamine class, which generally provides rapid fungicidal activity and requires shorter treatment courses compared with many azole antifungals. It is particularly effective against dermatophytes, making it a preferred option for tinea infections.

Store the product at ambient temperature, away from direct sunlight and moisture. Keep it in the original container with the lid tightly closed to maintain stability and prevent contamination.

Apply a thin layer of the cream or gel to the affected area once or twice daily, as directed by a healthcare professional. Gently rub it in until fully absorbed, and continue use for the full prescribed period, even if symptoms improve.

Serious but rare risks include severe allergic reactions such as swelling, hives, difficulty breathing, and rare skin conditions like Stevens‑Johnson syndrome. If any of these occur, discontinue use immediately and seek medical attention.

Individuals with known hypersensitivity to terbinafine or any component of the formulation should avoid using the product. It is also contraindicated on severely damaged, inflamed or infected skin without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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