Product image of Kruidvat Noodanticonceptie Ulipristal (Ulipristal Acetate) supplied by GNH India

Kruidvat Noodanticonceptie Ulipristal

Active Ingredient:
Ulipristal Acetate
Origin:
EU

Kruidvat Noodanticonceptie Ulipristal (Ulipristal Acetate)

Ulipristal acetate, the active ingredient in Kruidvat Noodanticonceptie Ulipristal, is a selective progesterone receptor modulator presented as an oral formulation for oral use. It is employed as emergency contraception to delay or inhibit ovulation and thereby prevent fertilisation in women of reproductive age.

GNH India supplies Kruidvat Noodanticonceptie Ulipristal as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Medical Valley Invest Ab

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Indications & Clinical Uses

Ulipristal acetate is a selective progesterone receptor modulator used in emergency contraception to prevent pregnancy after unprotected intercourse.

  • Unprotected intercourse: provides effective contraception when taken within 120 hours after exposure.
  • Contraceptive failure: offers an alternative to copper IUD when other emergency methods are unavailable.
  • Late‑cycle contraception: can be used in the luteal phase when regular hormonal methods are not feasible.

How It Works

  • Ulipristal acetate binds selectively to progesterone receptors in the hypothalamus and ovary, acting as a modulator that blocks the progesterone‑mediated luteinising hormone surge. By delaying or inhibiting ovulation, it prevents the release of an oocyte and thus blocks fertilisation. The drug does not interfere with implantation once fertilisation has occurred.

Side Effects

Ulipristal acetate may cause a range of adverse reactions. Most are mild and resolve without intervention.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Headache: transient tension‑type headache.
  • Fatigue: feeling of tiredness or low energy.
  • Abdominal pain: cramp‑like discomfort in the lower abdomen.
  • Menstrual changes: spotting or delayed next period.
  • Dizziness: brief episodes of light‑headedness.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Liver injury: jaundice, dark urine, or elevated liver enzymes.
  • Persistent vomiting: may lead to dehydration.
  • Severe abdominal pain: could indicate ovarian torsion.
  • Anaphylaxis: rapid onset of systemic hypersensitivity.
  • Thromboembolic events: rare clot formation in veins or arteries.

Precautions & Warnings

Before using Kruidvat Noodanticonceptie Ulipristal, consider the following safety measures.

  • Timing of administration: take as soon as possible after unprotected intercourse, ideally within 5 days.
  • Pregnancy status: confirm that the user is not already pregnant before taking the tablet.
  • Hormonal contraception: avoid initiating combined hormonal contraceptives on the same day, as efficacy may be reduced.
  • Known hypersensitivity: do not use if the individual has a documented allergy to ulipristal acetate or any excipients.
  • Drug interactions: be aware of concomitant use of strong CYP3A4 inducers which may lower effectiveness.
  • Store at ambient temperature: keep in the original pack, protect from moisture and excessive heat.

Avoid Interactions

Ulipristal acetate can interact with other medicines, influencing its efficacy or safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin): may markedly reduce contraceptive effectiveness.
  • Simultaneous initiation of combined hormonal contraceptives: can diminish the emergency pill’s action.

Moderate Interactions (Monitor Closely)

  • Anticonvulsants (e.g., valproate): may modestly lower drug levels.
  • Antiretroviral agents (e.g., efavirenz): potential reduction in efficacy.
  • Herbal supplements such as St. John’s wort: may decrease plasma concentration.
  • Hormone‑based therapies (e.g., hormone replacement): monitor for reduced contraceptive effect.

Frequently Asked Questions

Kruidvat Noodanticonceptie Ulipristal is an oral emergency‑contraception product. It is taken after unprotected sexual intercourse or contraceptive failure to reduce the risk of pregnancy by delaying or inhibiting ovulation. The medication is intended for women of reproductive age who need a post‑coital contraceptive option.

Ulipristal acetate acts as a selective progesterone receptor modulator. By binding to progesterone receptors in the hypothalamus and ovary, it blocks the luteinising hormone surge that triggers ovulation. This delay or inhibition of ovulation prevents the release of an egg, thereby reducing the chance of fertilisation and subsequent pregnancy.

The exact dose is determined by the prescribing healthcare professional. In most clinical settings a single oral tablet is administered, but the prescriber may adjust the regimen based on individual medical history, timing of intercourse, and other relevant factors. Patients should follow the specific instructions provided by their clinician.

The product is not intended for use during an established pregnancy, and its safety in pregnant women has not been established. Limited data are available regarding use while breastfeeding; therefore, a healthcare provider should be consulted to weigh potential risks and benefits before administration to nursing mothers.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams across international markets. After the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any required cold‑chain handling), and import documentation.

Ulipristal acetate remains effective up to 120 hours after unprotected intercourse, whereas levonorgestrel’s efficacy declines sharply after 72 hours. Ulipristal also works in later phases of the menstrual cycle by more directly inhibiting ovulation, making it a preferred option for later‑presenting users. Both are oral tablets, but ulipristal generally offers higher overall pregnancy‑prevention rates.

Store the tablets at ambient temperature, below 25 °C, in the original packaging to protect them from moisture and direct sunlight. Keep the container tightly closed and out of reach of children. Do not use the product if the packaging is damaged or if the tablets appear discoloured.

The medication is taken orally, usually as a single tablet, with or without water. It should be swallowed whole and not chewed or crushed. For optimal effectiveness, it is recommended to take the tablet as soon as possible after the unprotected event, ideally within the first 24 hours.

Serious adverse reactions, although rare, include severe allergic responses such as anaphylaxis, liver injury indicated by jaundice or dark urine, and persistent vomiting that may lead to dehydration. If any of these symptoms occur, medical attention should be sought immediately. Users should also be alert for signs of severe abdominal pain.

The product should be avoided by individuals with a known hypersensitivity to ulipristal acetate or any of its excipients. It is also contraindicated in women who are already pregnant, and caution is advised for those taking strong CYP3A4‑inducing drugs, as efficacy may be compromised. Consultation with a healthcare professional is essential before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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