Product image of Kruidvat (Paracetamol) supplied by GNH India

Kruidvat

Active Ingredient:
Paracetamol
Origin:
EU

Kruidvat (Paracetamol)

Paracetamol, the active ingredient in Kruidvat, is an analgesic presented as an oral tablet for oral use. It is classified as a pain reliever and antipyretic and is commonly employed to treat mild to moderate pain such as headache, muscular aches, and to lower elevated body temperature in both adults and children when taken as directed.

GNH India supplies Kruidvat as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies, hospitals and clinics worldwide. The company adheres to stringent quality standards and regulatory requirements across EU markets.

Manufacturer / TM Owner

Vemedia Manufacturing B. V.

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Indications & Clinical Uses

Paracetamol acts centrally to alleviate pain and reduce fever.

  • Headache: provides relief of tension‑type and mild migraine pain.
  • Fever: lowers elevated body temperature in febrile illnesses.
  • Muscular pain: eases soreness associated with minor strains or over‑exertion.
  • Toothache: reduces discomfort from dental pain.
  • Arthralgia: helps manage mild joint pain.

How It Works

  • Paracetamol inhibits prostaglandin synthesis in the central nervous system by blocking the cyclooxygenase (COX) pathway, primarily COX‑3, which reduces the formation of pain‑inducing and fever‑inducing prostaglandins, thereby providing analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset after ingestion.
  • Abdominal discomfort: transient stomach pain.
  • Rash: mild skin irritation or itching.
  • Dizziness: occasional light‑headedness.

Serious or Rare Side Effects

  • Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatotoxicity: liver injury, especially with overdose or chronic high dosing.
  • Blood disorders: rare cases of agranulocytosis or thrombocytopenia.
  • Anaphylaxis: rare allergic reaction requiring immediate medical attention.

Precautions & Warnings

Paracetamol should be used with attention to specific safety considerations.

  • Dosage adjustment: reduce dose in patients with hepatic impairment.
  • Alcohol consumption: avoid excessive alcohol while using.
  • Allergy: discontinue if hypersensitivity reactions occur.
  • Pregnancy: use only if benefit outweighs risk (Category B).
  • Drug interactions: review concomitant medications for potential interactions.
  • Store at ambient temperature: keep below 25°C in the original pack, protect from moisture.

Avoid Interactions

Paracetamol can interact with several medicines; monitoring is advised.

Major Interactions (Avoid)

  • Warfarin: may increase anticoagulant effect and bleeding risk.
  • Isoniazid: combined use raises risk of hepatotoxicity.
  • Carbamazepine: may reduce paracetamol efficacy.
  • Alcohol: potentiates liver toxicity.

Moderate Interactions (Monitor Closely)

  • Ciprofloxacin: may increase plasma concentration of paracetamol.
  • Phenobarbital: may increase metabolism, lowering effectiveness.

Frequently Asked Questions

Kruidvat Paracetamol is used to relieve mild to moderate pain such as headache, muscular aches, toothache, and to reduce fever. It is an over‑the‑counter analgesic and antipyretic commonly employed in adults and children when taken according to label directions.

Paracetamol works by inhibiting the synthesis of prostaglandins in the central nervous system, primarily through blocking the COX‑3 enzyme. This reduces the formation of chemicals that signal pain and raise body temperature, providing analgesic and antipyretic effects without strong peripheral anti‑inflammatory activity.

The appropriate dose of Kruidvat Paracetamol is determined by the prescribing healthcare professional based on the patient’s age, weight, and clinical condition. Patients should follow the dosage instructions on the product label or those provided by their doctor or pharmacist.

Paracetamol is classified as Category B for pregnancy, indicating that it is generally considered safe when used at the recommended dose and only if the benefit outweighs any potential risk. It is also excreted in breast milk in small amounts, and short‑term use is usually regarded as compatible with breastfeeding, but consultation with a healthcare provider is advised.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Compared with non‑steroidal anti‑inflammatory drugs (NSAIDs), paracetamol provides effective pain relief and fever reduction without the gastrointestinal irritation or platelet inhibition associated with NSAIDs. However, it lacks significant anti‑inflammatory activity, so for conditions where inflammation is a major component, an NSAID may be preferred.

Kruidvat Paracetamol should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use it after the expiry date printed on the label.

Kruidvat Paracetamol is taken orally, usually with a glass of water. The tablet should be swallowed whole and not chewed or crushed unless the product label specifically permits it. Dosing intervals and total daily dose should follow the instructions provided by a healthcare professional.

The most serious risks include severe liver injury, especially with overdose or chronic high dosing, and rare but life‑threatening skin reactions such as Stevens‑Johnson syndrome. Patients should avoid exceeding the recommended maximum daily dose and seek immediate medical attention if they notice signs of liver dysfunction or severe skin rash.

Individuals with known hypersensitivity to paracetamol or any of the tablet excipients should avoid it. Patients with severe liver disease, chronic alcohol misuse, or those taking medications that strongly interact with paracetamol (e.g., certain anticoagulants) should consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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