Kybernin P 500 - Antithrombin III

Trade Name : Kybernin P 500

Csl Behring Switzerland

Vials

Strength 500IE
In Stock

Storage/Handling:

Store at room temperature at a maximum of 25°C. Do not freeze.


Uses of Kybernin P 500 - Antithrombin III:

Used in the treatment of Prophylaxis and treatment of thromboembolic complications in:
1. Hereditary deficiency of antithrombin III
2. Acquired deficiency of antithrombin III


Product Introduction:

Kybernin P is recommended as a replacement therapy for individuals diagnosed with congenital antithrombin III deficiency in the following circumstances:

- Prevention of thrombosis in situations where the administration of oral anticoagulants or heparin is contraindicated, particularly during surgery and during pregnancy.

- Treatment of thrombosis in cases of extensive thrombosis combined with heparin as well as in cases of disseminated intravascular coagulation. In cases of congenital deficiency, the dosage should be individualized for each patient. Here, the family history with regard to thromboembolic events, the actual clinical risk factors, and the laboratory assessment should be taken into account.

The dosage and duration of substitution therapy for acquired deficiency are contingent upon factors such as the individual's plasma antithrombin level, the presence of indicators of heightened turnover, the underlying medical condition, and the severity of clinical symptoms. Determining the appropriate amount and frequency of administration should always rely on a case-specific assessment of clinical effectiveness and laboratory results.


Pack Size: 1s

Pack Size refers to the Quantity of Packs available in 1 order

Delivery Process

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You can fill in a request for your medicine through the form provided. You can access the form by clicking on the ‘Get Price’ button.

Submit a Request

You can fill in a request for your medicine through the form provided. You can access the form by clicking on the ‘Get Price’ button.

Side Effects of Kybernin P 500 - Antithrombin III:

Patients should be informed with the early signs of Hypersensitivity reactions-
- Angiodema
- Hives
- Generalized urticaria
- Tightness of the chest
- Wheezing
- Hypotension
- Anaphylaxsis (including shock) (severe case)
- Headache
- Burning and stinging at infusion site
- Chills
- Flushing
- Lethargy
- Nausea
- Tightness of chest
- Tingling
- Vomiting


Drug Interactions:

The presence of heparin significantly amplifies the effectiveness of antithrombin. However, when antithrombin is replaced while administering therapeutic doses of heparin, it raises the potential for bleeding complications. It should be kept in mind that the half-life of antithrombin may be substantially shortened in certain clinical conditions, such as disseminated intravascular coagulation due to accelerated antithrombin turnover. Therefore the patient should be increasingly monitored.


How Kybernin P 500 - Antithrombin III Works:

Kybernin P 500 Injection contains an active ingredient antithrombin 3 and it works by inactivating the thrombin.


How To Use Kybernin P 500 - Antithrombin III:

The dosage and duration of the substitution therapy in acquired deficiency depends on the plasma antthrombin level, the presence of signs for increased turnover, the underlying disorder, and the severity of the clinical condition. The amount to be administered and the frequency of administration should always be based on the clinical efficacy and laboratory assessment in the indiavidual case.


Safety Instructions For Kybernin P 500 - Antithrombin III:

Alcohol svgALCOHOL Exercise Caution Safety of Kybernin P 500 for use with alcohol has not been established. Please consult your doctor. Pregnancy svgPREGNANCY Unsafe Kybernin P 500 may not be safe for use during pregnancy. Exercise caution and consult your doctor before use. BREAST FEEDINGBREAST FEEDING Consult your Doctor Kybernin P 500 may not be safe for use during lactation. Exercise caution and consult your doctor before use. Driving svgDriving Safe Driving is considered safe even during the consumption of Kybernin P 500


Habit Forming

No


Remember:

1. 40-60 IU antithrombin per kg of body weight per day depending on the coagulation status.
2. In congenital deficiency, dosage should be individualised for each patient taking into account the family history with regard to thromboembolic events, the actual clinical risk factors and the laboratory assessment.
3. The number of units of antithrombin administered is expressed in International Units (IU), which are related to the current WHO standard for antithrombin.
4. Has a shelf life of 3 years
5. Once the container has been opened the contents have to be used immediately.
6. It is highly advisable to record the name and batch number of the Kybernin product every time it is administered to a patient. This practice helps maintain a clear association between the patient and the specific product batch.
7. Kybernin P 500 should be administered to pregnant and lactating antithrombin deficient women only if clearly indicated takin into consideration that pregnancy confers an increased risk of thrombeombolic events in these patients.
8. The reconstituted product should be inspected visually for participate matter and discoloration prior to administration. The solution should appear clear or mildly opalescent. Avoid using solutions that appear cloudy or contain deposits.


FAQs:

1. What if we missed the dose?

If you happen to miss a dose, take it as soon as you realize it. However, if your next scheduled dose is approaching, simply skip the missed one and continue with your regular dosing routine. Do not take an additional dose to compensate for the one you missed. If you are regularly missing doses,consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses

2. What happens if i overdose?

Do not use more than prescribed dose. Increasing your medication dosage will not enhance your symptoms; instead, it could lead to poisoning or severe side effects.

3. Is it safe to drive or operate heavy machinery when using this product?

Do not operate a vehicle if taking this medication causes drowsiness, dizziness, or significantly reduces your blood pressure. Please monitor your body for these effects when using Kybernin P 500 Injection.

4. Is this medicine or product addictive or habit forming?

The majority of medications do not carry a risk of addiction or abuse. Also, do not self-medicate and increase your body's dependence on medicines without the advice of a doctor.

5. How to dispose of the Kypernin P 500?

Do not flush medications down the toilet or pour them into the drain unless instructed to do so. Disposing of medication in this way can potentially pollute the environment. Please consult your pharmacist or doctor for more details on how to safely discard Kybernin P 500 Injection.

Product information is meant for

Wholesalers Suppliers Exporters Doctors MOH Tender Supplies Hospitals Brand CROs Comparator Supplies Generic Cooperate Sourcing Individual Patients Indian Institutional Buyers

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Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Kybernin P 500 - Antithrombin III which is also known as Kybernin P 500 and Manufactured by Csl Behring Switzerland. It is available in strength of 500IE per ml. Read more

Kybernin P 500 - Antithrombin III is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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