Kyleena (Levonorgestrel)

Levonorgestrel released from the device binds to progesterone receptors in the cervical mucus and endometrium. This thickens the mucus to block sperm, thins the uterine lining, and suppresses ovulation, creating conditions that prevent fertilisation and implantation.

Kyleena is supplied as a pre‑loaded intrauterine system that releases a fixed low dose of levonorgestrel continuously. The exact dosing regimen is determined by the prescribing clinician based on the product’s specifications and the patient’s clinical needs.

Kyleena must not be used by women who are pregnant; it is intended for contraception in non‑pregnant individuals. After insertion, breastfeeding is generally considered safe, but patients should discuss any concerns with their healthcare provider.

To place an order, submit an enquiry on the Kyleena product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Kyleena and other levonorgestrel‑releasing IUSs such as Mirena share a similar mechanism but differ in size, hormone release rate and approved duration of use. Compared with copper IUDs, Kyleena delivers hormonal contraception, which can reduce menstrual bleeding, whereas copper devices are non‑hormonal and may increase bleeding.

Kyleena should be stored at ambient temperature, below 25 °C, in its original sealed packaging. Protect the device from moisture, direct sunlight and extreme temperatures to maintain its integrity until insertion.

Kyleena is inserted by a trained healthcare professional into the uterine cavity using a specialised inserter. The procedure is performed in a clinical setting, typically after confirming a negative pregnancy test and ensuring the patient has no contraindications.

Serious risks include uterine perforation during insertion, device expulsion or displacement, and pelvic inflammatory infection. Although rare, an ectopic pregnancy can occur if contraception fails. Patients should seek immediate medical attention if they experience severe abdominal pain, fever or abnormal bleeding.

Kyleena is contraindicated in women with active pelvic infection, unexplained vaginal bleeding, known or suspected uterine anomalies, current pregnancy, or a history of hormone‑sensitive cancers. It should also be avoided in individuals with severe liver disease or those who are allergic to levonorgestrel or the device’s materials.