Kynteles - Vedolizumab

Trade Name : Kynteles

Takeda Austria Gmbh

Vials

Strength 300mg
In Stock

Storage/Handling:

Store in refrigerator at 2°C - 8°C. Do not let it freeze.


Uses of Kynteles - Vedolizumab:

Used in the treatment of -
Ulcerative colitis
Crohn’s disease


Product Introduction:

Kynteles Injection, commonly known as Entvyio, is a medication prescribed for various conditions such as ulcerative colitis and Crohn’s disease. It effectively alleviates symptoms associated with these disorders, including pain, redness, and swelling.

Administration of Kynteles Injection should be performed by a healthcare professional and not attempted by the patient. To maximize its benefits, it is essential to use the medication regularly at the same time each day. Even if symptoms improve, it is crucial to follow the doctor's recommendations and complete the prescribed dose.

While Kynteles Injection is generally well-tolerated, some common side effects may include nasopharyngitis, headache, arthralgia, nausea, fever, upper respiratory tract infection, and fatigue. If these side effects persist or worsen over time, consulting with a doctor is advised, and they can provide guidance on managing or preventing these symptoms.

Prior to taking Kynteles Injection, it is important to inform your doctor about any existing heart, kidney, or liver issues. Additionally, disclose all other medications you are currently taking. Pregnant and breastfeeding women should seek advice from their healthcare providers before initiating this medication to ensure its safety in such situations. Following these guidelines helps ensure the medicine's effectiveness while prioritizing your overall health and well-being.


Pack Size: 1s

Pack Size refers to the Quantity of Packs available in 1 order

Expiry - 7/25

Delivery Process

Submit a Request

You can fill in a request for your medicine through the form provided. You can access the form by clicking on the ‘Get Price’ button.

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Once we review your request, we’ll send you an estimated price for the medicine within 2-5 days.

Confirmation and Payment

You can fill in a request for your medicine through the form provided. You can access the form by clicking on the ‘Get Price’ button.

Submit a Request

You can fill in a request for your medicine through the form provided. You can access the form by clicking on the ‘Get Price’ button.

Benefits of Kynteles - Vedolizumab:

1. Ulcerative Colitis: Kynteles is used in adults with moderately to severely active ulcerative colitis who haven't responded well to conventional treatment or lost their response to other medications like tumor necrosis factor (TNF) alpha antagonists.

2. Crohn's Disease: Kynteles is used in adults with moderately to severely active Crohn's disease who also haven't had sufficient response to conventional treatment or lost their response to TNF alpha antagonists.


Side Effects of Kynteles - Vedolizumab:

Though Kynteles 300mg Vedolizumab offers hope for managing moderate to severe IBD, like any medication, it carries the potential for side effects. It's crucial to be aware of these before embarking on treatment, so you can make informed decisions alongside your doctor.

Common vedolizumab side effects-
#Upper respiratory tract infections.
#Headache
#Nausea and vomiting
#Diarrhea
#Joint and back pain
#Fatigue
#Fever
#Skin reactions

Less common vedolizumab side effects-
#Infections
#Severe allergic reactions
#Infusion-related reactions
#Liver problems

Rare common vedolizumab side effects- -
#Progressive multifocal leukoencephalopathy (PML)
#Cancers


Drug Interactions:

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with kynteles 300mg injection and can cause undesirable side effects, especially if you are under immunosuppressant or corticosteroid therapy.

Drug-Drug Interaction: Kynteles 300 mg Inj may interact with live vaccines, Natalizumab, TNF blockers (infliximab, etanercept, adalimumab, golimumab), etc.

Drug-Food Interaction: Avoid alcohol consumption and smoking.

Drug-Disease Interaction: Kynteles 300 vedolizumab should be used with caution in patients with liver or kidney disease, weak immune systems, and serious infections.


How Kynteles - Vedolizumab Works:

Kynteles works by targeting alpha4beta7 integrins, which are proteins found on the surface of certain white blood cells. These cells play a role in the inflammation process associated with IBD. By binding to these integrins, Kynteles prevents these white blood cells from reaching the inflamed areas in the gut, reducing inflammation and improving symptoms.


Safety Instructions For Kynteles - Vedolizumab:

Alcohol svgALCOHOL Unsafe Limit or avoid alcohol consumption while taking Kynteles. Alcohol can increase the risk of side effects like nausea, vomiting, and dizziness, and may affect the medication's effectiveness. Consult your doctor about safe alcohol intake during treatment. Pregnancy svgPREGNANCY Unsafe Do not use Kynteles 300mg during pregnancy. There is limited data on its safety in pregnant women and potential risks to the developing fetus. Discuss alternative treatment options with your doctor if needed. BREAST FEEDINGBREAST FEEDING Unsafe Stop breastfeeding while taking Kynteles 300mg inj. Vedolizumab medication can pass through breast milk and potentially harm your baby. Talk to your doctor about safe feeding options during treatment. Driving svgDriving Caution Exercise caution when driving or operating machinery after receiving vedolizumab. The medication can cause dizziness and fatigue, which may impair your judgment and coordination. Consult your doctor about potential driving restrictions. LIVER svgLIVER Caution Inform your doctor of any pre-existing liver problems before taking Kynteles 300mg. The medication can affect liver function, and your doctor may need to adjust the dosage or monitor you closely. KIDNEY svgKIDNEY Inform your doctor Disclose any kidney problems to your doctor. Similar to the liver, kidneys can be impacted by Kynteles 300mg, requiring dosage adjustments or close monitoring. Children  svgCHILDREN Not recommended Kynteles 300mg is not approved for use in children. The safety and effectiveness haven't been established in this age group.


Habit Forming

No


Remember:

1. Tell your doctor or nurse immediately if you experience a rash, itching, difficulty breathing or swallowing, swelling of the eyes, mouth, throat, tongue, or lips, dizziness or a fast heartbeat during or after administration of Kynteles Injection.
2. Inform your doctor if you have liver problems, tuberculosis or have been in close contact with someone with tuberculosis, if you currently have an infection, or infections that come and go or ongoing infections that do not go away.
Inform your doctor if you are going to have any vaccinations or if you have had one recently.
3. Tell your doctor or nurse immediately if you experience a rash, itching, difficulty breathing or swallowing, swelling of the eyes, mouth, throat, tongue, or lips, dizziness or a fast heartbeat during or after administration of Kynteles Injection.
4. Inform your doctor if you have liver problems, tuberculosis or have been in close contact with someone with tuberculosis, if you currently have an infection, or infections that come and go or ongoing infections that do not go away.
5. Inform your doctor if you are going to have any vaccinations or if you have had one recently.


FAQs:

1. Is Kynteles a self-administered injection?

No, Kynteles should be administered by a healthcare professional and should not be self-administered by the patient.

2. How often should Kynteles injections be taken?

The frequency of Kynteles injections may vary based on the individual's treatment plan. It is typically administered at specific intervals as determined by the prescribing healthcare provider.

3. Can Kynteles be used for other conditions besides ulcerative colitis and Crohn's disease?

Kynteles is specifically indicated for the treatment of ulcerative colitis and Crohn's disease and is not approved for other conditions.

4. Who shouldn't use Kynteles 300mg?

Individuals with a history of hypersensitivity to Vedolizumab or any of the other ingredients in the medication.
People with active serious infections.
Pregnant or breastfeeding women.

5. What are the common side effects of Kynteles 300 mg injection?

Common side effects may include nasopharyngitis, headache, arthralgia, nausea, fever, upper respiratory tract infection, and fatigue.

6. Should Kynteles be taken even if symptoms improve?

Yes, it is important to continue using Kynteles as recommended by the doctor, even if symptoms improve. Abruptly stopping the medication may impact its effectiveness.

GNH India exports Kynteles 300 Vedolizumab to various countries such as UK, Netherlands, Ireland, Australia and New Zealand.


Product information is meant for

Wholesalers Suppliers Exporters Doctors MOH Tender Supplies Hospitals Brand CROs Comparator Supplies Generic Cooperate Sourcing Individual Patients Indian Institutional Buyers

Disclaimer

Trade Marks displayed in compliance with provisions of: Trademark Act, 1999 u/s 30 and 30 (1) of "Fair use"

GNH India is WHO GDP and ISO 9001 2015 Certified Pharmaceutical Wholesaler/ Supplier/ Exporters/ Importer from India of Kynteles - Vedolizumab which is also known as Kynteles and Manufactured by Takeda Austria Gmbh. It is available in strength of 300mg per ml. Read more

Kynteles - Vedolizumab is supplied for Tenders/ Emergency imports/ Un - licensed, Specials, Orphan drug/ Name patient line/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples For Clinical trials.  Click to know price.     Read less

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

We deliver your medicines through a validated cold chain shipment process. This process is used as these medicines need to manufactured, transported and stored at very specific temperatures, utilizing thermal and refrigerated packaging methods.

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