Product image of L-Flox IV Infusion (Levofloxacin) 500mg Injection supplied by GNH India

L-Flox IV Infusion

Active Ingredient:
Levofloxacin
Form:
Injection

L-Flox IV Infusion (Levofloxacin Injection) 500mg

L-Flox IV Infusion is a prescription fluoroquinolone antibacterial agent containing Levofloxacin as its active ingredient. Administered intravenously, this 500mg strength injection is utilized to treat severe bacterial infections when oral therapy is not feasible or appropriate. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes required for bacterial DNA replication, transcription, repair, and recombination.

Strength

500mg

Pack Size

1s

Storage

Ambient

1
Pack/s
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Indications & Clinical Uses

  • L-Flox IV Infusion is indicated for the treatment of adults with mild, moderate, or severe infections caused by susceptible strains of designated microorganisms. Key clinical indications include community-acquired pneumonia, nosocomial pneumonia, complicated urinary tract infections, acute pyelonephritis, and complicated skin and skin structure infections.

Side Effects

  • Common side effects associated with L-Flox IV Infusion include nausea, headache, diarrhea, constipation, dizziness, and localized injection site reactions. Serious adverse reactions associated with fluoroquinolones include tendonitis, tendon rupture, peripheral neuropathy, central nervous system effects (such as convulsions or anxiety), and prolongation of the QT interval. Patients should contact their healthcare provider immediately if they experience joint pain, muscle weakness, tingling sensations, or severe skin rashes.

Precautions & Warnings

  • L-Flox IV Infusion should be used with caution in patients with known predisposing factors for seizures, renal impairment, or a history of tendon disorders. Dosage adjustments are required for patients with impaired renal function. This medication is classified under Pregnancy Category C and should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus. Patients should avoid excessive sunlight or artificial UV exposure during treatment due to the risk of phototoxicity.

Avoid Interactions

  • Levofloxacin may interact with class IA or class III antiarrhythmic agents, potentially increasing the risk of QT interval prolongation. Concomitant administration with nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the risk of central nervous system stimulation and convulsive seizures. Systemic corticosteroids can elevate the risk of tendon rupture, and concurrent use of antidiabetic agents requires close monitoring of blood glucose levels due to the risk of hypoglycemia or hyperglycemia.

Frequently Asked Questions

L-Flox IV Infusion is prescribed for the treatment of moderate to severe bacterial infections, including community-acquired pneumonia, nosocomial pneumonia, complicated urinary tract infections, acute pyelonephritis, and complicated skin infections.

L-Flox IV Infusion is administered as a slow intravenous infusion by a qualified healthcare professional in a clinical setting. It is not intended for self-administration.

Levofloxacin, like other fluoroquinolones, carries warnings regarding the risk of tendonitis, tendon rupture, peripheral neuropathy, central nervous system effects, and the exacerbation of muscle weakness in patients with myasthenia gravis.

L-Flox IV Infusion is classified as Pregnancy Category C. It should only be used during pregnancy if the potential therapeutic benefit to the mother outweighs the potential risks to the developing fetus, as determined by a medical professional.

Yes, Levofloxacin can interact with several drugs, including certain antiarrhythmics, NSAIDs, systemic corticosteroids, and antidiabetic medications. Always inform your healthcare provider of all medications you are currently taking.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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