Product image of L-Optic (Levofloxacin) supplied by GNH India

L-Optic

Active Ingredient:
Levofloxacin
Origin:
EU

L-Optic (Levofloxacin)

Levofloxacin, the active ingredient in L-Optic, is a fluoroquinolone antibiotic presented as an ophthalmic solution for ocular use. It treats bacterial conjunctivitis, bacterial keratitis and other ocular bacterial infections in patients requiring prescription therapy.

GNH India supplies L-Optic as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

S.C. Rompharm Company S.R.L.

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Indications & Clinical Uses

Levofloxacin is a fluoroquinolone antibiotic used to treat bacterial infections of the eye.

  • Bacterial conjunctivitis: reduces bacterial load and resolves inflammation.
  • Bacterial keratitis: eradicates causative organisms and promotes corneal healing.
  • Other ocular bacterial infections: controls infection and prevents complications.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription. By binding to the ATP‑binding sites of these enzymes, it prevents DNA supercoiling and strand separation, leading to bacterial cell death. This bactericidal action covers a broad range of Gram‑positive and Gram‑negative ocular pathogens.

Side Effects

Levofloxacin ophthalmic solution may cause ocular and systemic adverse reactions.

Common Side Effects

  • Eye irritation: transient burning or stinging after use.
  • Redness: mild conjunctival hyperemia.
  • Tearing: increased lacrimation.
  • Blurred vision: temporary visual disturbance.

Serious or Rare Side Effects

  • Corneal ulceration: worsening corneal lesions.
  • Severe allergic reaction: eyelid swelling, rash, or anaphylaxis.
  • Tendon rupture: rare systemic tendon injury.

Precautions & Warnings

When prescribing L-Optic, clinicians should observe several safety precautions.

  • Assess allergy: confirm no known hypersensitivity to fluoroquinolones or ophthalmic preservatives.
  • Monitor ocular surface: watch for signs of worsening inflammation or corneal damage.
  • Use as directed: limit duration to the prescribed period to reduce resistance risk.
  • Avoid contact lenses: discontinue lens wear during treatment unless advised.
  • Caution in systemic disease: consider renal or hepatic impairment when systemic absorption is possible.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Levofloxacin ophthalmic may interact with certain systemic and topical agents.

Major Interactions (Avoid)

  • Systemic fluoroquinolones: concurrent use may increase risk of tendon toxicity.
  • Anticholinergic eye drops: may reduce drug absorption.
  • Non‑steroidal anti‑inflammatory eye drops: potential for additive ocular irritation.

Moderate Interactions (Monitor Closely)

  • Corticosteroid eye preparations: may mask infection signs.
  • Anticoagulants: systemic absorption could potentiate bleeding risk.
  • Herbal supplements (e.g., ginkgo): monitor for tendon‑related effects.

Frequently Asked Questions

L-Optic is an ophthalmic formulation containing levofloxacin, a fluoroquinolone antibiotic indicated for the treatment of bacterial infections of the eye, such as bacterial conjunctivitis, bacterial keratitis, and other ocular bacterial infections. It is prescribed by eye care professionals to eradicate pathogenic bacteria and promote healing of the ocular surface.

Levofloxacin exerts its antibacterial effect by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. These enzymes are essential for DNA replication and transcription. By binding to their ATP‑binding sites, levofloxacin prevents DNA supercoiling and strand separation, leading to bacterial cell death. This mechanism provides broad‑spectrum activity against Gram‑positive and Gram‑negative ocular pathogens.

The dosing regimen for L‑Optic is determined by the prescribing ophthalmologist based on the specific infection, severity, and patient factors. Typical regimens involve one to several drops instilled into the affected eye(s) at defined intervals, such as every two to four hours initially, followed by a reduced frequency. The exact dose and duration must be individualized and written on the prescription.

Safety data for levofloxacin ophthalmic use during pregnancy or lactation are limited. Because systemic absorption can occur, the drug should be used only if the potential benefit justifies the potential risk to the fetus or infant. Healthcare providers should evaluate the risk‑benefit profile and consider alternative treatments when possible.

To place an order, visit the product page for L‑Optic on the GNH India website (gnhindia.com) and submit an enquiry with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

L‑Optic’s active ingredient, levofloxacin, belongs to the fluoroquinolone class, offering broad‑spectrum coverage against many Gram‑positive and Gram‑negative bacteria, including some resistant strains. Compared with older agents such as chloramphenicol or macrolides, levofloxacin often provides faster bacterial eradication and a lower risk of resistance development, though it may carry a higher risk of tendon‑related adverse events.

L‑Optic should be stored at room temperature, preferably below 25 °C, in its original container to protect it from moisture and direct sunlight. Keep the vial tightly closed when not in use and avoid freezing. If the product appears discolored or contains particles, discard it and obtain a new supply.

L‑Optic is applied topically to the eye as an ophthalmic solution. The patient should wash their hands, tilt the head back, and pull down the lower eyelid to create a small pocket. One or more drops are instilled into the conjunctival sac as prescribed, avoiding contact between the tip of the bottle and the eye or any surface to maintain sterility.

The most serious adverse reactions to levofloxacin eye drops include corneal ulceration or worsening of existing corneal lesions, severe allergic responses such as anaphylaxis, and systemic tendon rupture, although the latter is rare. Patients should be instructed to seek immediate medical attention if they experience intense eye pain, sudden vision loss, swelling of the eyelids, or systemic tendon pain.

L‑Optic should be avoided in individuals with a documented hypersensitivity to levofloxacin, other fluoroquinolones, or any component of the ophthalmic formulation. Caution is also advised for patients with a history of tendon disorders, myasthenia gravis, or those taking concomitant systemic fluoroquinolones, as the risk of adverse effects may be heightened.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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