Product image of L-Thyroxin Bc (Levothyroxine Sodium) supplied by GNH India

L-Thyroxin Bc

Active Ingredient:
Levothyroxine Sodium
Origin:
EU

L-Thyroxin Bc (Levothyroxine Sodium)

Levothyroxine Sodium, the active ingredient in L-Thyroxin Bc, is a thyroid hormone presented as an oral tablet for oral use. It replaces deficient thyroid hormone in patients with hypothyroidism, supports thyroid hormone replacement therapy, and helps manage goiter.
GNH India supplies L-Thyroxin Bc as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Berlin-Chemie Ag

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Indications & Clinical Uses

L‑Thyroxin Bc is a synthetic thyroid hormone that acts on the hypothalamic‑pituitary‑thyroid axis to restore normal hormone levels.

  • Hypothyroidism: restores euthyroid status and relieves fatigue, weight gain, and cold intolerance.
  • Thyroid hormone replacement therapy: maintains stable thyroid function after thyroidectomy or radioactive iodine treatment.
  • Goiter: reduces thyroid gland enlargement by normalising circulating hormone concentrations.

How It Works

  • Levothyroxine Sodium is a synthetic form of the endogenous hormone thyroxine (T4). After oral absorption, it enters the bloodstream and is converted to the active triiodothyronine (T3) within peripheral tissues. The hormone binds nuclear thyroid‑hormone receptors, modulating gene transcription, increasing basal metabolic rate, and regulating protein synthesis and growth.

Side Effects

Adverse reactions may occur, ranging from mild to severe.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Palpitations: transient increase in heart rate.
  • Insomnia: difficulty falling or staying asleep.
  • Gastrointestinal upset: nausea or abdominal discomfort.
  • Weight loss: unintended reduction in body weight.

Serious or Rare Side Effects

  • Allergic reaction: rash, pruritus, or angioedema.
  • Cardiac arrhythmia: atrial fibrillation or tachyarrhythmias.
  • Osteoporosis: decreased bone mineral density with long‑term overtreatment.
  • Myocardial ischemia: chest pain in patients with coronary disease.

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Cardiovascular disease: assess risk of tachycardia or arrhythmia.
  • Diabetes mellitus: monitor glucose control as thyroid status can affect insulin sensitivity.
  • Adrenal insufficiency: ensure adequate glucocorticoid replacement before starting.
  • Pregnancy or lactation: evaluate benefit‑risk ratio with a healthcare professional.
  • Elderly patients: start with lower doses and titrate cautiously.
  • Store at ambient temperature: keep below 25 °C, retain in original container, protect from moisture and direct sunlight.

Avoid Interactions

Levothyroxine may interact with several medicines, altering its absorption or effect.

Major Interactions (Avoid)

  • Calcium supplements: significantly reduce levothyroxine absorption.
  • Iron salts: impair oral uptake when taken concurrently.
  • Antacids containing aluminum or magnesium: decrease bioavailability.

Moderate Interactions (Monitor Closely)

  • Warfarin: may potentiate anticoagulant effect; monitor INR.
  • Amiodarone: can alter thyroid hormone metabolism.
  • Selective serotonin reuptake inhibitors (SSRIs): may increase risk of abnormal heart rhythm.

Frequently Asked Questions

L‑Thyroxin Bc contains levothyroxine sodium, a synthetic thyroid hormone used to treat hypothyroidism, provide thyroid hormone replacement after thyroidectomy or radioactive iodine therapy, and manage goiter by normalising circulating thyroid hormone levels.

Levothyroxine sodium is a synthetic form of T4 that is absorbed from the gastrointestinal tract, converted to the active T3 in peripheral tissues, and binds nuclear thyroid‑hormone receptors. This interaction regulates gene transcription, increases basal metabolic rate, and supports normal growth and metabolism.

The appropriate dose of L‑Thyroxin Bc is individualized. A qualified prescriber determines the exact amount based on the patient’s age, weight, severity of hypothyroidism, and laboratory thyroid‑stimulating hormone (TSH) levels. No standard dosing regimen is provided here.

Safety data for levothyroxine sodium in pregnancy and lactation are limited, and the product’s pregnancy category is listed as unknown. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and treatment decisions must be made by a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

L‑Thyroxin Bc is a levothyroxine‑only formulation, providing a stable source of synthetic T4. Alternative products may combine T4 with T3 (liothyronine) or use different salt forms. Levothyroxine‑only therapy is generally preferred for most patients because it mimics natural thyroid hormone physiology and offers predictable dosing.

Store the tablets at ambient temperature, preferably below 25 °C. Keep them in the original blister pack or container, protect from moisture, heat, and direct sunlight. Do not store in bathrooms or near kitchen appliances that generate steam.

L‑Thyroxin Bc is taken orally, usually with a full glass of water. It is commonly recommended to take the tablet on an empty stomach, at least 30‑60 minutes before breakfast, to optimise absorption and minimise interactions with food or supplements.

Serious risks include allergic reactions such as rash or angioedema, cardiac arrhythmias (especially atrial fibrillation) in susceptible individuals, myocardial ischemia, and long‑term bone loss leading to osteoporosis when overtreatment causes excessive thyroid hormone levels.

Patients with untreated thyrotoxicosis, acute myocardial infarction, or uncorrected adrenal insufficiency should avoid levothyroxine therapy until those conditions are managed. Additionally, individuals with known hypersensitivity to levothyroxine sodium or any excipients in the tablet should not use the product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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