Product image of L-Thyroxin Henning (Levothyroxine Sodium) supplied by GNH India

L-Thyroxin Henning

Active Ingredient:
Levothyroxine Sodium
Origin:
EU

L-Thyroxin Henning (Levothyroxine Sodium)

Levothyroxine sodium, the active ingredient in L-Thyroxin Henning, is a thyroid hormone replacement presented as an oral tablet for oral use. It is used to treat hypothyroidism, provide hormone replacement after thyroidectomy, and manage goiter.
GNH India supplies L-Thyroxin Henning as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sanofi-Aventis Deutschland Gmbh

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Indications & Clinical Uses

L-Thyroxin Henning is a synthetic thyroid hormone that acts on the endocrine system to restore normal thyroid function.

  • Hypothyroidism: restores adequate thyroid hormone levels, normalising metabolism and energy.
  • Post‑thyroidectomy hormone replacement: provides necessary T4 to maintain euthyroid status after thyroid removal.
  • Goiter: helps normalise thyroid activity, which can reduce gland enlargement.

How It Works

  • Levothyroxine sodium is a synthetic form of the thyroid hormone thyroxine (T4). After oral absorption, it is converted to the active hormone triiodothyronine (T3) within cells, where it binds nuclear thyroid hormone receptors. This receptor activation modulates gene transcription, increasing basal metabolic rate, protein synthesis, and overall metabolic activity throughout the body.

Side Effects

Levothyroxine may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Headache: occasional mild to moderate pain.
  • Nausea: transient gastrointestinal discomfort.
  • Weight gain: modest increase due to metabolic changes.
  • Fatigue: feeling of tiredness, especially during dose adjustments.

Serious or Rare Side Effects

  • Chest pain or palpitations: may indicate cardiac arrhythmia.
  • Severe allergic reaction (anaphylaxis): rare but requires immediate medical attention.
  • Bone loss (osteoporosis) with long‑term high doses: increased fracture risk.

Precautions & Warnings

When prescribing or dispensing L-Thyroxin Henning, consider the following precautions:

  • Dose adjustment: titrate based on TSH levels and clinical response.
  • Cardiovascular monitoring: use caution in patients with coronary artery disease or arrhythmias.
  • Pregnancy: prescribe only if benefits outweigh potential risks.
  • Elderly: initiate therapy at a lower dose due to increased sensitivity.
  • Drug interactions: review concomitant medications that may affect levothyroxine absorption or metabolism.
  • Store at ambient temperature: keep below 25°C, protect from moisture and light in the original container.

Avoid Interactions

Levothyroxine can interact with several medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid)

  • Calcium or iron supplements: significantly reduce levothyroxine absorption.
  • Antacids containing aluminum or magnesium: impair gastrointestinal uptake.
  • Cholesterol‑lowering agents such as cholestyramine: decrease drug effectiveness.

Moderate Interactions (Monitor Closely)

  • Warfarin: levothyroxine may enhance anticoagulant effect, requiring INR monitoring.
  • Corticosteroids: may increase thyroid hormone metabolism, necessitating dose review.
  • Selective serotonin reuptake inhibitors (e.g., sertraline): can alter thyroid hormone levels, warranting periodic assessment.

Frequently Asked Questions

L-Thyroxin Henning is a prescription oral tablet containing levothyroxine sodium. It is used to replace deficient thyroid hormone in patients with hypothyroidism, to provide hormone replacement after thyroidectomy, and to manage goiter by normalising thyroid function.

Levothyroxine is a synthetic form of the natural thyroid hormone T4. After absorption, it is converted to the active hormone T3 inside cells, where it binds nuclear thyroid receptors. This binding regulates gene expression, increasing basal metabolic rate, protein synthesis, and overall metabolic activity.

The appropriate dose of L-Thyroxin Henning is individualized. A qualified prescriber determines the exact amount based on the patient’s serum TSH levels, weight, age, cardiac status, and response to therapy. No fixed regimen should be assumed without medical guidance.

Levothyroxine is generally considered safe in pregnancy when the benefits outweigh potential risks, as untreated hypothyroidism can harm both mother and fetus. It is excreted in breast milk in small amounts; breastfeeding mothers should continue therapy under physician supervision.

To order L-Thyroxin Henning, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details, and necessary import documentation.

L-Thyroxin Henning contains levothyroxine, the standard T4 replacement used globally. Compared with liothyronine (T3) preparations, levothyroxine offers a longer half‑life and more stable serum levels, making it the preferred first‑line therapy for most hypothyroid patients.

Store L-Thyroxin Henning tablets at ambient temperature, below 25 °C, in the original blister pack to protect from moisture and light. Keep the product out of reach of children and avoid exposure to excessive heat or humidity.

L-Thyroxin Henning is taken orally, usually once daily on an empty stomach, at least 30 minutes before breakfast. Swallow the tablet whole with a full glass of water; do not crush or chew unless specifically instructed by a healthcare professional.

Serious risks include cardiac arrhythmias such as atrial fibrillation, especially in patients with underlying heart disease, and bone loss (osteoporosis) with prolonged high‑dose therapy. Rarely, severe allergic reactions can occur. Patients should report chest pain, palpitations, or unexplained fractures promptly.

L-Thyroxin Henning should be avoided in individuals with untreated adrenal insufficiency, acute thyrotoxicosis, or uncorrected hyperthyroidism. Patients with known hypersensitivity to levothyroxine or any tablet excipients should also refrain from using this medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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