Product image of Laberon (Beclometasone Dipropionate, Formoterol Fumarate Dihydrate) supplied by GNH India

Laberon

Active Ingredient:
Beclometasone Dipropionate, Formoterol Fumarate Dihydrate
Origin:
EU

Laberon (Beclometasone Dipropionate, Formoterol Fumarate Dihydrate)

Beclometasone dipropionate, the active ingredient in Laberon, is a corticosteroid/long‑acting β2‑agonist combination presented as an inhalation aerosol for inhalation use. It is indicated for long‑term maintenance therapy in asthma and chronic obstructive pulmonary disease (COPD) in adults. The formulation delivers both anti‑inflammatory and bronchodilatory effects, helping to reduce airway hyper‑responsiveness and improve lung function, thereby decreasing the frequency of exacerbations and the need for rescue medication.

GNH India supplies Laberon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, and clinics worldwide, ensuring consistent quality and regulatory compliance across global markets.

Manufacturer / TM Owner

Stada Arzneimittel Ag

1
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Indications & Clinical Uses

Laberon, a corticosteroid/long‑acting β2‑agonist inhaler, is used in the management of chronic respiratory diseases.

  • Asthma: provides long‑term control of symptoms and reduces the risk of exacerbations.
  • COPD: improves airflow limitation and decreases symptom burden in maintenance therapy.
  • Exercise‑induced bronchoconstriction: may be used for prevention in patients already on maintenance therapy.

How It Works

  • Beclometasone dipropionate binds to intracellular glucocorticoid receptors, modulating gene transcription to suppress airway inflammation. Formoterol fumarate selectively stimulates β2‑adrenergic receptors on bronchial smooth muscle, increasing cyclic AMP levels and causing prolonged bronchodilation. The combined actions result in reduced airway hyper‑responsiveness and improved airflow over time.

Side Effects

Common Side Effects

  • Oral thrush or candidiasis
  • Hoarseness or dysphonia
  • Cough or throat irritation
  • Headache
  • Tremor or shakiness
  • Palpitations

Serious or Rare Side Effects

  • Paradoxical bronchospasm
  • Adrenal suppression with systemic effects
  • Severe allergic reactions (anaphylaxis)
  • Pneumonia or respiratory infections
  • Cardiac arrhythmias
  • Hyperglycaemia in susceptible patients

Precautions & Warnings

Before initiating therapy, consider the following precautions:

  • Assess for active respiratory infections: treat infection before starting.
  • Monitor for oral candidiasis: advise rinsing mouth after inhalation.
  • Evaluate cardiovascular status: caution in patients with arrhythmias or hypertension.
  • Use the lowest effective dose: adjust based on symptom control.
  • Avoid abrupt discontinuation: taper if long‑term high‑dose use.
  • Store at room temperature: keep in original container, protect from moisture and heat.

Avoid Interactions

Major Interactions (Avoid)

  • Beta‑blockers: may diminish bronchodilator effect and provoke bronchospasm.
  • Potent CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): increase systemic corticosteroid exposure.
  • Other inhaled or systemic corticosteroids: risk of additive glucocorticoid effects.

Moderate Interactions (Monitor Closely)

  • Diuretics: may enhance hypokalaemia when combined with β2‑agonists.
  • Sympathomimetic agents (e.g., epinephrine): additive cardiovascular stimulation.
  • Ritonavir or other strong CYP3A4 inhibitors: monitor for increased side effects.
  • Fluconazole: may modestly raise systemic corticosteroid levels.

Frequently Asked Questions

Laberon is a combination inhaler containing beclometasone dipropionate and formoterol fumarate. It is prescribed for the long‑term maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD) in adult patients, helping to control symptoms and reduce exacerbations.

Beclometasone dipropionate binds to glucocorticoid receptors in airway cells, altering gene expression to suppress inflammation, reduce mucus production, and decrease airway swelling, thereby improving airflow and symptom control.

The prescribed dose of Laberon is determined by the treating physician based on the severity of the disease, patient response, and clinical guidelines. Patients should follow the specific inhalation instructions provided by their healthcare professional.

Safety data for Laberon in pregnancy and lactation are limited. The decision to use it should be made by a qualified healthcare provider after weighing the potential benefits against any possible risks to the mother and infant.

To order Laberon, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Laberon combines an inhaled corticosteroid with a long‑acting β2‑agonist, offering both anti‑inflammatory and bronchodilator effects in a single device. This dual action can improve adherence compared with separate inhalers, while providing comparable efficacy to other combination products such as budesonide/formoterol or fluticasone/salmeterol.

Laberon should be stored at room temperature, below 25 °C, in its original packaging. Keep the inhaler away from excessive heat, moisture and direct sunlight to maintain product stability and performance.

Laberon is delivered via an inhalation aerosol (metered‑dose inhaler). The patient inhales a prescribed number of puffs, typically once or twice daily, using a slow, deep breath followed by a breath‑hold to ensure optimal drug deposition in the lungs.

Serious risks include paradoxical bronchospasm, adrenal suppression with high systemic corticosteroid exposure, severe allergic reactions (anaphylaxis), and rare cardiac arrhythmias. Patients should be monitored for these events, especially during the initial treatment period.

Laberon is contraindicated in patients with known hypersensitivity to beclometasone, formoterol, or any component of the inhaler. It should also be avoided in individuals with untreated acute asthma attacks, severe cardiovascular disorders, or those taking non‑selective β‑blockers.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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