Product image of Labrycor (Isoprenaline Hydrochloride) supplied by GNH India

Labrycor

Active Ingredient:
Isoprenaline Hydrochloride
Origin:
EU

Labrycor (Isoprenaline Hydrochloride)

Isoprenaline Hydrochloride, the active ingredient in Labrycor, is a beta‑adrenergic agonist presented as an injectable solution for intravenous use. It is employed to increase heart rate, improve myocardial contractility, and provide bronchodilation in acute clinical settings.\nGNH India supplies Labrycor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Macure Healthcare Limited

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Indications & Clinical Uses

  • Isoprenaline Hydrochloride acts on the cardiovascular and respiratory systems to manage acute rhythm and airway conditions.\n\nBradycardia: raises heart rate to correct symptomatic slow rhythm.\nHeart block: improves conduction to alleviate block-related bradyarrhythmias.\nAsthma (bronchospasm): relaxes airway smooth muscle to relieve acute bronchoconstriction.\nHypotension: increases cardiac output and vascular tone to support blood pressure.

How It Works

  • Isoprenaline Hydrochloride is a non‑selective beta‑adrenergic receptor agonist that binds to β1 and β2 receptors, stimulating adenylate cyclase and raising intracellular cAMP. The resulting cascade enhances calcium influx in cardiac myocytes, increasing heart rate and contractility, while β2 activation relaxes bronchial smooth muscle and dilates peripheral vessels.

Side Effects

  • Adverse reactions may occur with intravenous administration of Isoprenaline Hydrochloride.\n\nCommon Side Effects:\n- Tachycardia: excessive increase in heart rate.\n- Palpitations: awareness of rapid heartbeat.\n- Tremor: fine muscle shaking.\n- Headache: mild to moderate pain.\n\nSerious or Rare Side Effects:\n- Arrhythmias: potentially life‑threatening rhythm disturbances.\n- Myocardial ischemia: reduced blood flow to heart muscle.\n- Severe hypotension: abrupt drop in blood pressure.\n- Allergic reactions: rash, itching, or anaphylaxis.

Precautions & Warnings

  • Careful monitoring is required when using Isoprenaline Hydrochloride intravenously.\n\nCardiac monitoring: observe heart rate and rhythm throughout infusion.\nBlood pressure monitoring: watch for hypertension or hypotension.\nAsthma caution: monitor for paradoxical bronchospasm.\nRecent myocardial infarction: avoid due to risk of ischemia.\nStore at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

  • Isoprenaline Hydrochloride can interact with several cardiovascular agents.\n\nMajor Interactions (Avoid):\n- Beta‑blockers: antagonize therapeutic effect and may cause severe bradycardia.\n- Calcium channel blockers: additive cardiac effects increase arrhythmia risk.\n- MAO inhibitors: potentiate cardiovascular stimulation.\n\nModerate Interactions (Monitor Closely):\n- Diuretics: may enhance hypotensive response.\n- Digitalis glycosides: increased risk of arrhythmias.

Frequently Asked Questions

Labrycor contains Isoprenaline Hydrochloride and is used intravenously to treat acute bradycardia, heart block, severe asthma bronchospasm, and hypotension by stimulating beta‑adrenergic receptors to raise heart rate, improve cardiac contractility, and relax airway smooth muscle.

Isoprenaline Hydrochloride is a non‑selective beta‑adrenergic agonist. It binds to β1 receptors in the heart and β2 receptors in the lungs and vasculature, activating adenylate cyclase, increasing cAMP, and thereby enhancing heart rate, myocardial force of contraction, and bronchodilation.

The specific dose of Labrycor is determined by the prescribing clinician based on the patient’s condition, weight, and response. Dosage regimens are individualized and should follow the prescriber’s orders and institutional protocols.

Safety data for Isoprenaline Hydrochloride in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To order Labrycor, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Labrycor (Isoprenaline) is a non‑selective beta‑agonist, providing both β1 and β2 stimulation, whereas agents like Dobutamine are more β1‑selective. Isoprenaline offers stronger bronchodilatory effects, making it useful for asthma, but it may cause more tachycardia compared with more cardio‑selective alternatives.

Labrycor should be stored at ambient temperature, below 25 °C, in its original packaging. Protect it from direct light, moisture, and extreme temperatures. Do not freeze the product, and inspect the vial for particulate matter before use.

Labrycor is administered by intravenous infusion under continuous clinical supervision. The solution is typically diluted in a compatible carrier fluid and infused at a rate prescribed by the treating physician, with vital signs monitored throughout the administration.

Serious risks include life‑threatening arrhythmias, myocardial ischemia, severe hypotension, and allergic reactions such as anaphylaxis. Immediate medical attention is required if any of these events occur during or after infusion.

Labrycor is contraindicated in patients with known hypersensitivity to Isoprenaline, uncontrolled ventricular tachyarrhythmias, recent myocardial infarction, severe aortic stenosis, or uncontrolled hypertension. Clinicians should assess each patient’s medical history before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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