Product image of Labrycor (Isoprenaline Hydrochloride) supplied by GNH India

Labrycor

Active Ingredient:
Isoprenaline Hydrochloride
Origin:
EU

Labrycor (Isoprenaline Hydrochloride)

Isoprenaline Hydrochloride, the active ingredient in Labrycor, is a beta‑adrenergic agonist presented as a sterile intravenous solution for use in acute cardiac and respiratory conditions. It increases heart rate and myocardial contractility and also relaxes bronchial smooth muscle, making it useful in managing bradyarrhythmias, heart block, asthma and bronchospasm.

GNH India supplies Labrycor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality and regulatory compliance across all markets, with reliable logistics and dedicated customer support.

Manufacturer / TM Owner

Macure Healthcare Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Isoprenaline Hydrochloride acts on the beta‑adrenergic system to treat several acute cardiac and respiratory disorders.

  • Bradyarrhythmias: restores adequate heart rate and improves cardiac output in patients with abnormally slow rhythms.
  • Heart block: increases conduction through the atrioventricular node, helping to overcome various degrees of block.
  • Asthma: relaxes bronchial smooth muscle, providing rapid relief of bronchospasm during acute attacks.
  • Bronchospasm: produces bronchodilation to improve airflow in severe bronchoconstriction episodes.

How It Works

  • Isoprenaline Hydrochloride is a non‑selective β‑adrenergic receptor agonist that binds to both β1 and β2 receptors. Activation of β1 receptors in the heart increases cyclic AMP, enhancing pacemaker activity and myocardial contractility, while β2 receptor stimulation in the lungs raises cyclic AMP in airway smooth muscle, causing relaxation and bronchodilation. The combined cardiac and pulmonary effects make it valuable in emergency management of bradyarrhythmias and bronchospasm.

Side Effects

Isoprenaline Hydrochloride may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Tachycardia: rapid increase in heart rate.
  • Palpitations: sensation of irregular or forceful heartbeats.
  • Tremor: fine shaking of hands or limbs.
  • Headache: mild to moderate cranial pain.

Serious or Rare Side Effects

  • Arrhythmias: potentially life‑threatening irregular heart rhythms.
  • Myocardial ischemia: reduced blood flow to heart muscle causing chest pain.
  • Severe bronchospasm paradox: unexpected worsening of airway constriction.

Precautions & Warnings

When using Isoprenaline Hydrochloride, careful monitoring and specific precautions are recommended to minimize risks.

  • Cardiac monitoring: continuous ECG and blood pressure should be observed during infusion.
  • Dose titration: start with the lowest effective dose and adjust gradually under medical supervision.
  • Contraindications: avoid use in patients with uncontrolled hyperthyroidism or severe hypertension.
  • Drug interactions: monitor closely when combined with other sympathomimetics or MAO inhibitors.
  • Store at ambient temperature: keep the solution below 25 °C, protected from light and moisture in the original container.

Avoid Interactions

Isoprenaline Hydrochloride interacts with several medications that can amplify or diminish its pharmacologic effects.

Major Interactions (Avoid)

  • Beta‑blockers: antagonize the drug’s action, potentially causing severe bradycardia.
  • Calcium channel blockers: additive negative inotropic effects may precipitate heart failure.

Moderate Interactions (Monitor Closely)

  • MAO inhibitors: may enhance catecholamine effects, increasing risk of hypertension.
  • Diuretics: can cause electrolyte imbalances that affect cardiac response.
  • Anticholinergic agents: may reduce bronchodilatory efficacy.

Frequently Asked Questions

Labrycor contains Isoprenaline Hydrochloride and is prescribed for acute management of bradyarrhythmias, various degrees of heart block, asthma attacks, and severe bronchospasm. By stimulating beta‑adrenergic receptors, it raises heart rate, improves cardiac output, and relaxes airway smooth muscle, providing rapid symptom relief in emergency settings.

Isoprenaline Hydrochloride is a non‑selective beta‑adrenergic agonist. It binds to β1 receptors in the heart, increasing cyclic AMP and enhancing pacemaker activity and contractility. Simultaneously, it activates β2 receptors in the lungs, raising cyclic AMP in airway smooth muscle, which leads to bronchodilation. The dual action supports both cardiac and respiratory function.

The appropriate dose of Labrycor is determined by the prescribing clinician based on the patient’s condition, severity, and response to therapy. Dosing is individualized, and the prescriber will set the infusion rate and duration according to clinical guidelines and monitoring parameters.

Safety data for Isoprenaline Hydrochloride in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Healthcare providers must evaluate each case carefully and discuss potential risks with the patient.

To order Labrycor, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After the request, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements) and assist with import documentation.

Labrycor’s active ingredient, Isoprenaline, is a non‑selective beta‑agonist, whereas alternatives such as epinephrine are also non‑selective but have a stronger alpha‑adrenergic component. Isoprenaline provides more pronounced β2‑mediated bronchodilation with less vasoconstriction, making it preferable when a primary focus on cardiac stimulation and bronchodilation is needed without significant peripheral vasoconstriction.

Labrycor should be stored at ambient temperature, preferably below 25 °C, in its original sealed container. Protect the solution from direct light, moisture, and extreme temperature fluctuations. Do not freeze. Before use, inspect for particulate matter or discoloration and discard any solution that appears compromised.

Labrycor is supplied as a sterile intravenous solution and is administered by a qualified healthcare professional via controlled IV infusion. The infusion rate is titrated to achieve the desired clinical effect while continuous monitoring of cardiac rhythm, blood pressure, and respiratory status is maintained throughout the administration.

Serious adverse reactions include life‑threatening arrhythmias, myocardial ischemia, and paradoxical severe bronchospasm. Patients may also develop profound tachycardia or hypertension. Immediate medical attention is required if any of these events occur, and continuous cardiac and respiratory monitoring is essential during treatment.

Labrycor is contraindicated in patients with uncontrolled hyperthyroidism, severe hypertension, or known hypersensitivity to isoprenaline or any formulation components. It should also be avoided in individuals taking high‑dose beta‑blockers or those with certain types of cardiac conduction disorders where increased heart rate could be harmful.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.