Product image of Lacerol Retard (Diltiazem) supplied by GNH India

Lacerol Retard

Active Ingredient:
Diltiazem
Origin:
EU

Lacerol Retard (Diltiazem)

Diltiazem, the active ingredient in Lacerol Retard, is a calcium channel blocker presented as an oral formulation for oral use. It is employed to manage hypertension, angina pectoris, and to control heart rate in atrial fibrillation, particularly in adult patients.

GNH India supplies Lacerol Retard as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for regulated markets. Our distribution network ensures timely delivery and compliance with local regulatory requirements.

Manufacturer / TM Owner

Lacer S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Diltiazem is a calcium channel blocker used to treat cardiovascular conditions.
  • Hypertension: lowers blood pressure by reducing peripheral vascular resistance.
  • Angina pectoris: relieves chest pain by decreasing myocardial oxygen demand.
  • Rate control in atrial fibrillation: slows ventricular response by inhibiting atrioventricular nodal conduction.

How It Works

  • Diltiazem blocks L-type calcium channels in cardiac and vascular smooth muscle cells, which reduces calcium influx. This leads to decreased myocardial contractility, slowed atrioventricular nodal conduction, and relaxation of vascular smooth muscle, resulting in lower heart rate and reduced systemic vascular resistance.

Side Effects

Common Side Effects

  • Headache: mild to moderate intensity.
  • Dizziness or light‑headedness, especially when standing.
  • Flushing: sensation of warmth and redness.
  • Peripheral edema: swelling of the ankles or feet.
  • Constipation or mild gastrointestinal discomfort.
  • Nausea: occasional upset stomach.

Serious or Rare Side Effects

  • Severe hypotension: marked drop in blood pressure.
  • Bradycardia: abnormally slow heart rate.
  • Heart block: impairment of electrical conduction.
  • Hepatic enzyme elevation: abnormal liver function tests.
  • Allergic reactions: rash, itching, or swelling.
  • Pulmonary edema: fluid accumulation in the lungs.

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Blood pressure monitoring: ensure baseline and periodic measurements.
  • Cardiac function assessment: evaluate for existing conduction abnormalities.
  • Drug interaction review: check concomitant medications that affect heart rate or blood pressure.
  • Hepatic impairment: adjust use in patients with liver disease.
  • Abrupt discontinuation: taper dose to avoid rebound hypertension.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Diltiazem may interact with several medicines; awareness helps prevent adverse outcomes. Major Interactions (Avoid):\n- Beta‑blockers: combined use can cause excessive bradycardia.

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): increase diltiazem plasma levels.
  • Digoxin: elevated digoxin concentrations may occur.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampin, carbamazepine): may reduce diltiazem effectiveness.
  • Diuretics: additive hypotensive effect.
  • NSAIDs: may diminish antihypertensive response.
  • Alcohol: can enhance dizziness and hypotension.
  • Grapefruit juice: may modestly increase diltiazem exposure.

Frequently Asked Questions

Lacerol Retard contains diltiazem, a calcium channel blocker prescribed to lower high blood pressure, relieve angina chest pain, and control heart rate in patients with atrial fibrillation. It is used in adult patients when these cardiovascular conditions require pharmacologic management.

Diltiazem blocks L‑type calcium channels in heart muscle and vascular smooth muscle. By reducing calcium entry, it decreases myocardial contractility, slows conduction through the atrioventricular node, and relaxes blood vessels, which together lower heart rate and blood pressure.

The appropriate dose of Lacerol Retard is determined by the prescribing clinician based on the patient’s condition, response, and other medical factors. Dosage adjustments are made according to clinical guidelines and individual therapeutic needs.

Safety of diltiazem in pregnancy or while breastfeeding has not been fully established. Healthcare providers should weigh potential benefits against possible risks and consider alternative therapies when appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Lacerol Retard (diltiazem) belongs to the calcium channel blocker class, which differs from beta‑blockers or nitrates in its mechanism of reducing calcium influx. It offers combined blood‑pressure lowering and heart‑rate control, making it useful when both effects are desired, whereas other classes may target only one aspect.

Lacerol Retard should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture and direct sunlight to maintain its stability and potency throughout its shelf life.

Lacerol Retard is taken orally, usually with a glass of water. The tablet should be swallowed whole and not crushed or chewed unless specifically instructed by a healthcare professional.

Serious risks include severe hypotension, marked bradycardia, heart block, and rare cases of liver enzyme elevation or allergic reactions. Patients should report symptoms such as faintness, slow heartbeat, chest discomfort, or skin rash to their physician promptly.

Lacerol Retard is contraindicated in patients with known hypersensitivity to diltiazem or other calcium channel blockers, those with severe sinus node dysfunction, second‑ or third‑degree atrioventricular block without a pacemaker, and in cases of acute myocardial infarction with cardiogenic shock.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Diltiazem

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT