Product image of Lacidipina Tecnigen (Lacidipine) supplied by GNH India

Lacidipina Tecnigen

Active Ingredient:
Lacidipine
Origin:
EU

Lacidipina Tecnigen (Lacidipine)

Lacidipine, the active ingredient in Lacidipina Tecnigen, is a calcium channel blocker presented as a tablet for oral use. It treats hypertension in adult patients. GNH India supplies Lacidipina Tecnigen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Tecnigen S.R.L.

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Indications & Clinical Uses

  • Lacidipine is a calcium‑channel blocker used primarily in the management of high blood pressure.
  • Hypertension: lowers blood pressure by reducing peripheral vascular resistance.
  • Essential hypertension: provides long‑acting control of systolic and diastolic pressures.
  • Secondary hypertension: may be added when other agents are insufficient.

How It Works

  • Lacidipine selectively inhibits L‑type calcium channels in vascular smooth muscle, preventing calcium influx that is necessary for contraction. This vasodilatory effect reduces peripheral vascular resistance, leading to a decrease in arterial blood pressure without significant impact on heart rate.

Side Effects

Lacidipine may cause a range of adverse reactions.

Common Side Effects

  • Headache
  • Flushing
  • Dizziness
  • Peripheral edema
  • Nausea
  • Tachycardia

Serious or Rare Side Effects

  • Severe hypotension
  • Myocardial infarction
  • Hepatic dysfunction
  • Allergic reactions including rash
  • Angioedema
  • Cardiac arrhythmias

Precautions & Warnings

Lacidipine should be used with careful clinical monitoring.

  • Dose titration: start with a low dose and adjust based on blood pressure response.
  • Renal impairment: monitor kidney function regularly.
  • Hepatic impairment: use cautiously and observe liver enzymes.
  • Concomitant antihypertensives: risk of additive hypotension, adjust doses accordingly.
  • Pregnancy: safety not established; avoid unless clearly needed.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Lacidipine can interact with several medicines.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole) may increase plasma levels.
  • Co‑administration with other calcium‑channel blockers can cause excessive hypotension.
  • Grapefruit juice can raise lacidipine concentrations.

Moderate Interactions (Monitor Closely)

  • Diuretics may enhance antihypertensive effect, requiring BP monitoring.
  • Beta‑blockers combined with lacidipine need careful blood pressure observation.
  • Non‑steroidal anti‑inflammatory drugs may reduce antihypertensive efficacy.

Frequently Asked Questions

Lacidipina Tecnigen contains lacidipine, a calcium‑channel blocker indicated for the treatment of hypertension. It helps lower elevated blood pressure by relaxing the smooth muscle of blood vessels, thereby reducing peripheral resistance and improving overall cardiovascular health in adult patients.

Lacidipine blocks L‑type calcium channels on vascular smooth‑muscle cells, preventing calcium entry that is required for muscle contraction. This inhibition leads to vasodilation, a decrease in peripheral vascular resistance, and ultimately a reduction in systemic arterial blood pressure.

The specific dose of lacidipine is individualized by the prescribing clinician based on the patient’s blood pressure, response to therapy, and any co‑existing medical conditions. The prescriber determines the appropriate starting dose and any subsequent adjustments.

Safety data for lacidipine in pregnancy and lactation are limited. It is generally advised to avoid use during pregnancy unless the potential benefit justifies the risk, and breastfeeding mothers should consult their healthcare provider before use.

To place an order, submit an enquiry on the Lacidipina Tecnigen product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lacidipine, as a dihydropyridine calcium‑channel blocker, offers potent vasodilation with a relatively low effect on heart rate, distinguishing it from non‑dihydropyridine agents. Compared with amlodipine, another dihydropyridine, lacidipine has a longer half‑life and may provide smoother blood‑pressure control, though clinical choice depends on individual patient factors.

Store the tablets at ambient temperature, preferably below 25 °C, in the original blister pack or container. Protect them from moisture, excessive heat and direct sunlight to maintain potency throughout the shelf life.

Lacidipina Tecnigen is taken orally, usually once daily. It can be swallowed with or without food; however, consistent administration with respect to meals may help maintain stable plasma levels. Patients should follow the prescriber’s instructions regarding timing and any dietary considerations.

Serious adverse events, though uncommon, include severe hypotension, myocardial infarction, hepatic dysfunction, allergic reactions such as rash or angioedema, and cardiac arrhythmias. Patients should seek immediate medical attention if they experience symptoms like fainting, chest pain, severe dizziness, jaundice or swelling of the face and throat.

Lacidipine is contraindicated in patients with known hypersensitivity to the drug or any other calcium‑channel blockers, in those with severe aortic stenosis, and in individuals with unstable angina or recent myocardial infarction where rapid blood‑pressure reduction could be harmful. Clinicians should also exercise caution in patients with significant liver or kidney disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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