Product image of Lacidipina Teva (Lacidipine) supplied by GNH India

Lacidipina Teva

Active Ingredient:
Lacidipine
Origin:
EU

Lacidipina Teva (Lacidipine)

Lacidipine, the active ingredient in Lacidipina Teva, is a calcium channel blocker presented as an oral dosage form for oral use. It treats hypertension in adults.

GNH India supplies Lacidipina Teva as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Italia S.R.L.

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Indications & Clinical Uses

  • Lacidipine is used to manage high blood pressure by relaxing vascular smooth muscle.
  • Hypertension: lowers systolic and diastolic blood pressure and reduces cardiovascular strain.
  • Essential hypertension: improves arterial compliance and long‑term blood pressure control.
  • Cardiovascular risk management: contributes to lowering the risk of hypertension‑related complications.

How It Works

  • Lacidipine selectively blocks L‑type calcium channels on vascular smooth muscle cells, inhibiting calcium influx. This vasodilatory effect reduces peripheral vascular resistance, leading to decreased arterial pressure without significant negative inotropic effects on the heart.

Side Effects

Adverse reactions may occur with any antihypertensive therapy.

Common Side Effects

  • Headache
  • Flushing
  • Peripheral edema
  • Dizziness or light‑headedness
  • Tachycardia
  • Palpitations

Serious or Rare Side Effects

  • Severe hypotension
  • Acute myocardial infarction
  • Angina pectoris
  • Elevated liver enzymes
  • Allergic skin reactions (rash, pruritus)
  • Hematologic abnormalities such as neutropenia

Precautions & Warnings

  • Safety considerations should be reviewed before initiating therapy.
  • Monitor blood pressure regularly: adjust dose based on therapeutic response.
  • Avoid abrupt discontinuation: taper under medical supervision to prevent rebound hypertension.
  • Caution in hepatic impairment: dose may need adjustment.
  • Use with caution in elderly patients: increased sensitivity to hypotensive effects.
  • Avoid concomitant use with strong CYP3A4 inhibitors: may raise plasma levels.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Potential drug‑drug interactions require clinical awareness.

Major Interactions (Avoid)

  • Co‑administration with other calcium channel blockers may cause additive hypotension.
  • Potent CYP3A4 inhibitors (e.g., clarithromycin, itraconazole) can increase lacidipine exposure.
  • Grapefruit juice: may markedly raise plasma concentrations.

Moderate Interactions (Monitor Closely):\n- Beta‑blockers: may enhance bradycardia or hypotensive effects.

  • Diuretics: risk of excessive blood pressure reduction.
  • ACE inhibitors or ARBs: monitor for additive antihypertensive effect.

Frequently Asked Questions

Lacidipina Teva contains lacidipine, a calcium channel blocker prescribed to lower elevated blood pressure in adults with hypertension. By relaxing arterial smooth muscle, it helps achieve target blood pressure levels and reduces the risk of hypertension‑related complications.

Lacidipine selectively inhibits L‑type calcium channels on vascular smooth muscle, preventing calcium entry that is necessary for muscle contraction. This inhibition causes vasodilation, decreasing peripheral vascular resistance and ultimately lowering systemic arterial pressure.

The appropriate dose of Lacidipina Teva is determined by the prescribing clinician based on the patient’s blood pressure, response to therapy, and any co‑existing medical conditions. The prescriber will select the strength and dosing schedule that best fits the individual’s needs.

Safety of lacidipine in pregnancy and lactation has not been definitively established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Lacidipine belongs to the dihydropyridine class of calcium channel blockers, offering potent vasodilation with a relatively long half‑life. Compared with other classes such as ACE inhibitors or beta‑blockers, it primarily reduces peripheral resistance and may be preferred when a strong arterial‑relaxing effect is desired.

Lacidipina Teva should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing in areas with high humidity.

Lacidipina Teva is taken orally, usually once daily, with or without food as directed by the prescribing physician. The tablet should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed.

Serious adverse events, although rare, can include severe hypotension, myocardial infarction, angina, significant liver enzyme elevation, and allergic reactions such as rash or anaphylaxis. Patients should seek immediate medical attention if they experience chest pain, fainting, or signs of an allergic response.

Lacidipina Teva is contraindicated in patients with known hypersensitivity to lacidipine or any component of the formulation, and in individuals with severe aortic stenosis or uncontrolled heart failure. Clinicians should also exercise caution in patients with significant hepatic impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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