Product image of Lacipil (Lacidipine) supplied by GNH India

Lacipil

Active Ingredient:
Lacidipine
Origin:
EU

Lacipil (Lacidipine)

Lacidipine, the active ingredient in Lacipil, is a dihydropyridine calcium channel blocker presented as a tablet for oral use. It is employed to lower elevated blood pressure in adult patients with hypertension. The medication is indicated for essential hypertension and may be used as part of combination therapy when monotherapy is insufficient.

GNH India supplies Lacipil as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation to support global distribution.

Manufacturer / TM Owner

Glaxosmithkline Trading Services Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lacidipine is used to treat hypertension by relaxing vascular smooth muscle and reducing peripheral resistance.

  • Essential hypertension: lowers systolic and diastolic blood pressure in patients with primary high blood pressure.
  • Isolated systolic hypertension: reduces elevated systolic pressure, especially in older adults.
  • Hypertension as adjunct therapy: may be combined with other antihypertensives when single‑drug control is inadequate.

How It Works

  • Lacidipine selectively blocks L‑type calcium channels in arterial smooth‑muscle cells. By inhibiting calcium influx, it prevents vascular smooth‑muscle contraction, leading to arterial vasodilation. The resulting decrease in peripheral vascular resistance lowers systemic blood pressure without significant effect on cardiac contractility, making it effective for managing essential hypertension.

Side Effects

Lacidipine may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Headache
  • Flushing
  • Peripheral edema
  • Dizziness

Serious or Rare Side Effects

  • Severe hypotension
  • Acute myocardial infarction
  • Angioedema

Precautions & Warnings

When prescribing Lacidipine, clinicians should observe several precautions to ensure safe use.

  • Blood pressure monitoring: regularly assess to avoid excessive hypotension.
  • Hepatic impairment: use with caution and consider dose adjustment in patients with liver dysfunction.
  • Elderly patients: start at low dose and monitor for orthostatic effects.
  • Concomitant antihypertensives: evaluate for additive blood‑pressure lowering effects.
  • Hypersensitivity: discontinue if allergic reaction occurs.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Lacidipine can interact with other medicines, influencing its plasma concentration or enhancing pharmacodynamic effects.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may markedly increase Lacidipine levels.
  • Grapefruit juice: can elevate drug exposure and risk of hypotension.
  • Co‑administration with other potent vasodilators: may cause dangerous drops in blood pressure.

Moderate Interactions (Monitor Closely)

  • Calcium supplements or antacids: may reduce oral absorption of Lacidipine.
  • Beta‑blockers: require monitoring of heart rate and blood pressure.
  • Diuretics: watch for electrolyte disturbances and additive hypotensive effect.

Frequently Asked Questions

Lacipil contains the active ingredient lacidipine, which is prescribed to lower high blood pressure in adults diagnosed with essential hypertension. It works as part of a treatment plan that may include lifestyle changes and, when needed, other antihypertensive agents.

Lacidipine blocks L‑type calcium channels in the smooth muscle of arteries. This inhibition reduces calcium entry into the cells, preventing contraction and causing the blood vessels to relax. The resulting vasodilation decreases peripheral resistance and lowers systemic blood pressure.

The appropriate dose of Lacipil is individualized by the prescribing healthcare professional based on the patient’s blood‑pressure readings, age, renal and hepatic function, and any concomitant medications. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for lacidipine in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and a healthcare provider should be consulted.

To request Lacipil, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lacipil belongs to the dihydropyridine calcium‑channel blocker class, which primarily causes arterial vasodilation. Compared with beta‑blockers or ACE inhibitors, it has a more pronounced effect on peripheral resistance and a lower impact on heart rate, making it useful when vasodilation is the desired primary mechanism.

Lacipil tablets should be stored at room temperature, below 25 °C, in the original packaging. They must be kept away from excess moisture, heat and direct sunlight to maintain stability and potency throughout their shelf life.

Lacipil is taken orally, usually once daily, with or without food as directed by a physician. The tablet should be swallowed whole with a glass of water and not crushed or chewed unless specifically instructed by a healthcare professional.

The most serious adverse events linked to Lacipil include severe hypotension, acute myocardial infarction and angioedema. Patients should be educated to recognize signs such as sudden dizziness, chest pain or swelling of the face and throat and seek immediate medical attention if they occur.

Lacipil is contraindicated in individuals with known hypersensitivity to lacidipine or any other dihydropyridine calcium‑channel blockers. It should also be avoided in patients with severe aortic stenosis or those who have experienced a prior severe hypotensive reaction to similar agents.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.