Product image of Lacipil (Lacidipine) supplied by GNH India

Lacipil

Active Ingredient:
Lacidipine
Origin:
EU

Lacipil (Lacidipine)

Lacidipine, the active ingredient in Lacipil, is a calcium channel blocker presented as a tablet for oral use. It treats hypertension in adult patients.

GNH India supplies Lacipil as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Glaxosmithkline Trading Services Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Lacidipine is used to manage high blood pressure by targeting vascular smooth‑muscle tone.
  • Hypertension: lowers systolic and diastolic pressure, reducing the risk of cardiovascular events.
  • Essential hypertension: provides sustained blood‑pressure control in patients requiring long‑term therapy.
  • Secondary hypertension: may be employed when blood‑pressure elevation is due to identifiable causes, as part of a comprehensive treatment plan.

How It Works

  • Lacidipine selectively inhibits L‑type calcium channels on vascular smooth‑muscle cells, preventing calcium influx. This leads to relaxation of arterial smooth muscle, decreased peripheral vascular resistance, and consequently a reduction in systemic blood pressure.

Side Effects

Lacidipine may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Flushing: transient warmth and redness.
  • Peripheral edema: swelling of ankles or feet.
  • Dizziness or light‑headedness.
  • Tachycardia: increased heart rate.
  • Nausea or abdominal discomfort.

Serious or Rare Side Effects

  • Severe hypotension: marked drop in blood pressure.
  • Angioedema: swelling of face, lips, or throat.
  • Hepatic dysfunction: elevated liver enzymes.
  • Myocardial infarction: rare cardiac event.
  • Life‑threatening arrhythmias.
  • Anaphylactic reactions: severe allergic response.

Precautions & Warnings

  • Before initiating Lacidipine therapy, consider the following safety measures.
  • Monitor blood pressure: ensure target levels are achieved without excessive drop.
  • Assess hepatic function: liver impairment may alter drug metabolism.
  • Review concomitant antihypertensives: avoid additive hypotensive effects.
  • Caution in elderly patients: increased sensitivity to blood‑pressure changes.
  • Avoid abrupt discontinuation: taper dose to prevent rebound hypertension.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Lacidipine can interact with several drug classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Other calcium‑channel blockers: additive vasodilatory effect.
  • Potent CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): increased plasma concentrations.
  • Grapefruit juice: may raise drug levels.
  • Concurrent antihypertensives causing profound hypotension.
  • Nitrates: risk of excessive blood‑pressure reduction.

Moderate Interactions (Monitor Closely)

  • Diuretics: may enhance antihypertensive effect.
  • Beta‑blockers: monitor heart rate and blood pressure.
  • ACE inhibitors or ARBs: watch for additive hypotension.
  • NSAIDs: possible reduction in antihypertensive efficacy.
  • CYP3A4 inducers (e.g., rifampicin): may lower drug exposure.

Frequently Asked Questions

Lacipil contains the active ingredient lacidipine, which is prescribed to lower high blood pressure (hypertension). By relaxing the smooth muscle in blood vessels, it helps maintain normal cardiovascular function and reduces the risk of complications associated with elevated blood pressure.

Lacidipine selectively blocks L‑type calcium channels on vascular smooth‑muscle cells. This inhibition prevents calcium entry, leading to muscle relaxation, decreased peripheral resistance, and a subsequent reduction in systemic blood pressure.

The appropriate dose of Lacipil is determined by the prescribing healthcare professional based on the individual’s medical condition, response to therapy, and other concurrent medications. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for lacidipine in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss alternatives with their healthcare provider.

To request Lacipil, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Lacipil belongs to the calcium‑channel blocker class, which differs from ACE inhibitors, beta‑blockers, and diuretics in its mechanism of relaxing vascular smooth muscle. It may be preferred when patients require a vasodilatory effect or have contraindications to other classes, but the choice depends on individual clinical factors.

Lacipil tablets should be stored at room temperature, below 25 °C, in the original packaging. Keep them away from moisture, direct sunlight, and excessive heat to maintain product stability.

Lacipil is taken orally, usually once daily, with or without food as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically instructed.

Serious adverse events, although rare, include severe hypotension, angioedema, hepatic dysfunction, myocardial infarction, and life‑threatening arrhythmias. Patients should seek immediate medical attention if they experience symptoms such as extreme dizziness, swelling of the face or throat, or chest pain.

Lacipil is contraindicated in patients with known hypersensitivity to lacidipine or any component of the formulation, and in those with severe aortic stenosis or uncontrolled heart failure. Caution is also advised for individuals with significant liver impairment or those taking interacting medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Lacidipine

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT