Product image of Lacosadel (Lacosamide) supplied by GNH India

Lacosadel

Active Ingredient:
Lacosamide
Origin:
EU

Lacosadel (Lacosamide)

Lacosamide, the active ingredient in Lacosadel, is a sodium channel blocker presented as an oral formulation for oral use. It is indicated as adjunctive therapy for partial‑onset seizures and primary generalized tonic‑clonic seizures in patients with epilepsy. The medication works by modulating neuronal excitability, helping to reduce seizure frequency in adults and children.

GNH India supplies Lacosadel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and procurement teams across multiple regions worldwide.

Manufacturer / TM Owner

Delorbis Pharmaceuticals Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Lacosamide is used in the management of epilepsy, targeting seizure activity.
  • Partial‑onset seizures: reduces seizure frequency when added to existing antiepileptic therapy.
  • Primary generalized tonic‑clonic seizures: provides adjunctive control of generalized seizure episodes.
  • Epilepsy (overall): contributes to improved seizure management as part of combination therapy.

How It Works

  • Lacosamide enhances the slow inactivation of voltage‑gated sodium channels, which stabilises hyper‑excitable neuronal membranes. By prolonging the inactive state of the channel, the drug reduces repetitive neuronal firing that underlies seizure generation, thereby decreasing the likelihood of seizure propagation in the central nervous system.

Side Effects

Adverse reactions may occur with Lacosamide use.

Common Side Effects

  • Dizziness
  • Nausea
  • Fatigue
  • Headache

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Cardiac arrhythmia (e.g., atrioventricular block)
  • Severe skin reactions such as exfoliative dermatitis

Precautions & Warnings

When prescribing Lacosamide, clinicians should consider several safety measures.

  • Cardiac monitoring: assess baseline ECG and monitor for conduction abnormalities.
  • Hepatic function: evaluate liver enzymes before initiation and periodically thereafter.
  • Drug interactions: review concomitant antiepileptic and CYP‑modulating agents.
  • Patient counseling: advise about possible dizziness and advise caution with operating machinery.
  • Discontinuation: avoid abrupt cessation to reduce risk of seizure worsening.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Lacosamide may interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Carbamazepine: induces metabolism, lowering lacosamide levels.
  • Phenytoin: induces metabolism, reducing therapeutic exposure.
  • Rifampin: strong enzyme inducer that decreases lacosamide concentration.

Moderate Interactions (Monitor Closely)

  • Valproate: may increase lacosamide plasma levels.
  • Oral contraceptives: efficacy can be reduced, requiring alternative contraception methods.

Frequently Asked Questions

Lacosadel contains lacosamide, an antiepileptic drug used as adjunctive therapy for partial‑onset seizures and primary generalized tonic‑clonic seizures in patients with epilepsy. It is prescribed when seizure control is not achieved with existing medication regimens.

Lacosamide enhances the slow inactivation of voltage‑gated sodium channels in neurons. This stabilises hyper‑excitable membranes, reduces repetitive firing, and limits the spread of seizure activity throughout the brain.

The specific dose of Lacosadel is determined by the prescribing clinician based on the patient’s age, weight, seizure type, and response to therapy. Dosage adjustments are made according to clinical guidelines and individual tolerability.

Safety data for lacosamide in pregnancy and lactation are limited. Clinicians should weigh the potential benefits against possible risks and consider alternative treatments when possible. Breastfeeding decisions should be made in consultation with a healthcare professional.

To request Lacosadel, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lacosamide belongs to the sodium channel blocker class and offers a distinct mechanism by enhancing slow inactivation, unlike many agents that target fast inactivation. It is generally well tolerated and may be preferred when patients experience side effects from other sodium‑channel blockers or need an alternative adjunctive option.

Lacosadel should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight and sources of heat to maintain stability.

Lacosadel is taken orally, usually as a tablet or capsule, with or without food. The exact administration schedule is set by the prescriber, who may start with a low dose and titrate upward based on therapeutic response and tolerability.

Serious adverse events include severe skin reactions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis, cardiac conduction abnormalities like atrioventricular block, and rare cases of suicidal ideation. Patients should be monitored closely for any signs of these conditions.

Lacosadel is contraindicated in patients with known hypersensitivity to lacosamide or any of its excipients. Caution is advised for individuals with pre‑existing cardiac conduction disorders, severe hepatic impairment, or those taking interacting enzyme‑inducing medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.