Product image of Lacosamid 1a Pharma (Lacosamide) supplied by GNH India

Lacosamid 1a Pharma

Active Ingredient:
Lacosamide
Origin:
EU

Lacosamid 1a Pharma (Lacosamide)

Lacosamide, the active ingredient in Lacosamid 1a Pharma, is an anticonvulsant presented as an oral tablet for oral administration. It is used to control partial‑onset seizures, including those that may secondarily generalize, in adult and pediatric patients with epilepsy.

GNH India supplies Lacosamid 1a Pharma as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide under strict quality standards and reliable logistics.

Manufacturer / TM Owner

1a Pharma Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Lacosamide is indicated for seizure disorders within the epilepsy therapeutic pathway.

  • Partial‑onset seizures: Reduces frequency of seizures when used as adjunctive therapy.
  • Adjunctive therapy in epilepsy: Improves overall seizure control when added to other antiepileptic drugs.
  • Secondary generalized seizures arising from focal onset: Helps prevent progression of focal seizures to generalized.

How It Works

  • Lacosamide enhances the slow inactivation of voltage‑gated sodium channels in neuronal membranes, stabilising hyper‑excitable neuronal cells. This modulation limits the repetitive firing of neurons and diminishes the propagation of abnormal electrical activity that underlies seizure generation.

Side Effects

Lacosamide may cause a range of adverse reactions, which are grouped by frequency.

Common Side Effects

  • Dizziness: Transient sensation of light‑headedness.
  • Nausea: Mild to moderate stomach upset.
  • Headache: Occasional tension‑type headache.
  • Fatigue: Generalised tiredness or lack of energy.

Serious or Rare Side Effects

  • Cardiac conduction abnormalities: PR‑interval prolongation that may lead to arrhythmia.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Suicidal ideation: Emergence of depressive thoughts or self‑harm urges.

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Renal impairment: Adjust dose in patients with reduced renal function.
  • Hepatic impairment: Use with caution; monitor liver enzymes.
  • Cardiac conduction: Monitor ECG for PR‑interval prolongation.
  • Pregnancy: Safety not established; weigh benefits against risks.
  • Concomitant CNS depressants: May enhance sedation; observe patient.
  • Store at ambient temperature: Keep below 25 °C, in original packaging, protected from moisture.

Avoid Interactions

Lacosamide can interact with several drug classes; awareness of the interaction level is essential.

Major Interactions (Avoid)

  • Class I antiarrhythmics (e.g., quinidine): May cause excessive PR‑interval prolongation.
  • Strong CYP3A4 inducers (e.g., carbamazepine): Reduce lacosamide plasma concentrations.
  • Other sodium‑channel blockers (e.g., phenytoin): Increase risk of cardiac effects.

Moderate Interactions (Monitor Closely)

  • Opioids: May increase central nervous system depression.
  • Alcohol: Enhances dizziness and drowsiness.
  • Antidepressants (e.g., SSRIs): Potential additive CNS effects.

Frequently Asked Questions

Lacosamid 1a Pharma contains lacosamide, an antiepileptic medication prescribed to treat partial‑onset seizures, including those that may secondarily generalize, in patients with epilepsy. It is used as adjunctive therapy to improve seizure control when combined with other antiepileptic drugs.

Lacosamide enhances the slow inactivation of voltage‑gated sodium channels in neuronal membranes. By stabilising hyper‑excitable neurons, it reduces the ability of abnormal electrical impulses to propagate, thereby decreasing seizure frequency.

The dosage of Lacosamid 1a Pharma is determined individually by a qualified prescriber based on the patient’s age, weight, renal and hepatic function, and response to therapy. The prescribing physician will set the appropriate starting dose and titration schedule.

Safety data for lacosamide in pregnancy and lactation are limited. The medication should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with older sodium‑channel blockers such as carbamazepine, lacosamide selectively enhances slow inactivation rather than fast inactivation, which may result in a different side‑effect profile and lower risk of certain drug‑drug interactions. Clinical choice depends on individual patient characteristics and therapeutic goals.

Store the product at ambient temperature, preferably below 25 °C, in the original packaging. Protect it from moisture and direct sunlight to maintain stability throughout its shelf life.

Lacosamid 1a Pharma is taken orally, usually as a tablet, with or without food as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush or split unless advised.

Serious adverse reactions, although rare, can include cardiac conduction abnormalities such as PR‑interval prolongation, severe skin reactions, suicidal ideation, and hypersensitivity reactions. Patients should be monitored for these events and seek immediate medical attention if they occur.

Individuals with known hypersensitivity to lacosamide or any excipients, patients with significant cardiac conduction disorders, and those taking contraindicated medications that may cause dangerous PR‑interval prolongation should avoid this product unless a specialist determines it is safe.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.