Product image of Lacosamid Jubilant (Lacosamide) supplied by GNH India

Lacosamid Jubilant

Active Ingredient:
Lacosamide
Origin:
EU

Lacosamid Jubilant (Lacosamide)

Lacosamide, the active ingredient in Lacosamid Jubilant, is an anticonvulsant presented as an oral tablet for oral use. It treats partial‑onset seizures in patients with epilepsy.
GNH India supplies Lacosamid Jubilant as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Jubilant Pharmaceuticals Nv

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Indications & Clinical Uses

  • Lacosamid Jubilant is an anticonvulsant indicated for the treatment of focal seizure disorders.
  • Partial‑onset seizures: Reduces seizure frequency when used as adjunctive therapy.
  • Epilepsy: Helps control focal seizures in patients with epilepsy.
  • Adjunctive therapy: Provides additional seizure control when combined with other antiepileptic drugs.

How It Works

  • Lacosamide enhances the slow inactivation of voltage‑gated sodium channels in neuronal membranes, stabilizing hyper‑excitable neurons and reducing repetitive firing that contributes to seizure generation. This selective modulation of sodium channel activity underlies its antiepileptic effect.

Side Effects

Lacosamide may cause a range of adverse reactions.

Common Side Effects

  • Dizziness
  • Fatigue
  • Nausea
  • Headache
  • Diplopia
  • Somnolence

Serious or Rare Side Effects

  • PR‑interval prolongation leading to cardiac conduction abnormalities
  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Suicidal thoughts or behavior
  • Hepatic dysfunction
  • Anaphylactic or severe allergic reactions
  • Respiratory depression

Precautions & Warnings

  • When prescribing Lacosamid Jubilant, clinicians should consider several safety aspects.
  • Renal impairment: Adjust dose or monitor renal function as needed.
  • Hepatic impairment: Monitor liver enzymes and consider dose modification.
  • Cardiac conduction disorders: Perform ECG monitoring for PR‑interval changes.
  • Pregnancy: Use only if the potential benefit outweighs any risk to the fetus.
  • Concomitant CNS depressants: Observe for enhanced sedation or respiratory effects.
  • Store at ambient temperature: Keep below 25 °C in the original container, protected from moisture and light.

Avoid Interactions

Lacosamide can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole) may increase lacosamide plasma levels.
  • Drugs that prolong the PR interval (e.g., class IA antiarrhythmics) can exacerbate cardiac conduction effects.

Moderate Interactions (Monitor Closely)

  • Co‑administration with other antiepileptic drugs may increase central nervous system depression.
  • Alcohol use may enhance sedation and dizziness.
  • Concurrent use with digoxin may require therapeutic drug monitoring.

Frequently Asked Questions

Lacosamid Jubilant contains lacosamide, an anticonvulsant indicated for the adjunctive treatment of partial‑onset (focal) seizures in patients with epilepsy. It helps reduce seizure frequency when added to existing therapy.

Lacosamide enhances the slow inactivation of voltage‑gated sodium channels, stabilizing hyper‑excitable neuronal membranes and limiting repetitive neuronal firing that underlies seizure activity. This selective modulation reduces the likelihood of seizure propagation.

The specific dosage regimen for Lacosamid Jubilant is determined by the prescribing clinician based on the patient’s age, weight, renal and hepatic function, and response to therapy. The prescriber will titrate the dose according to approved labeling.

Safety data for lacosamide in pregnancy are limited, and the product is classified as pregnancy category unknown. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus. Breastfeeding decisions should be made in consultation with a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

The primary alternative in the same class is carbamazepine, which also targets sodium channels but primarily affects fast inactivation. Lacosamide’s selective enhancement of slow inactivation may offer a different side‑effect profile, with less risk of certain dermatologic reactions, though both require monitoring for CNS and cardiac effects.

Lacosamid Jubilant should be stored at ambient temperature, below 25 °C, in its original container. Keep the product away from moisture, direct sunlight and heat sources to maintain stability throughout its shelf life.

The medication is taken orally, usually as a tablet, with or without food as directed by the prescriber. Swallow the tablet whole with water; do not crush or chew unless specifically instructed.

Serious adverse events associated with lacosamide include cardiac conduction abnormalities such as PR‑interval prolongation, severe skin reactions (e.g., Stevens‑Johnson syndrome), suicidal thoughts or behavior, and significant hepatic dysfunction. Patients should seek immediate medical attention if they experience palpitations, rash, mood changes, or jaundice.

Lacosamid Jubilant is contraindicated in patients with known hypersensitivity to lacosamide or any of its excipients. Caution is advised for individuals with pre‑existing cardiac conduction disorders, severe hepatic impairment, or those taking medications that markedly prolong the PR interval. The prescriber will assess suitability before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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