Product image of Lacosamid Viatris (Lacosamide) supplied by GNH India

Lacosamid Viatris

Active Ingredient:
Lacosamide
Origin:
EU

Lacosamid Viatris (Lacosamide)

Lacosamide, the active ingredient in Lacosamid Viatris, is an anticonvulsant presented as an oral formulation for oral use. It is indicated as adjunctive therapy for partial‑onset seizures in patients with epilepsy. GNH India supplies Lacosamid Viatris as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Viatris Aps

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Indications & Clinical Uses

  • Lacosamide is used in the management of focal epilepsy, acting on neuronal excitability to control seizure activity.
  • Partial‑onset seizures (adults): adjunctive therapy to reduce seizure frequency.
  • Partial‑onset seizures (adolescents): adjunctive therapy to reduce seizure frequency.
  • Focal epilepsy: adjunctive treatment to improve overall seizure control.

How It Works

  • Lacosamide selectively enhances the slow inactivation of voltage‑gated sodium channels in neuronal membranes. By stabilizing hyper‑excitable neuronal membranes, it reduces repetitive neuronal firing that underlies seizure generation, thereby contributing to seizure control when added to existing antiepileptic regimens.

Side Effects

Lacosamide may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Dizziness
  • Nausea
  • Headache
  • Somnolence
  • Diplopia
  • Fatigue

Serious or Rare Side Effects

  • PR‑interval prolongation or other cardiac conduction abnormalities
  • Severe skin reactions (e.g., Stevens‑Johnson syndrome)
  • Hypersensitivity reactions including anaphylaxis
  • Suicidal ideation or behavior
  • Significant hepatic enzyme elevations

Precautions & Warnings

  • When prescribing lacosamide, clinicians should consider several safety aspects.
  • Renal impairment: dose adjustment may be required based on renal function.
  • Cardiac conduction disorders: monitor ECG in patients with existing heart disease.
  • Concomitant CNS depressants: may increase sedation and dizziness.
  • Pregnancy: safety data are limited; use only if benefit outweighs risk.
  • Driving and operating machinery: patients should be cautioned about possible impairment.
  • Store at ambient temperature: keep below 25°C, retain original packaging, protect from moisture.

Avoid Interactions

Lacosamide can interact with other medicines, requiring careful management.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole) may increase lacosamide levels.
  • Strong CYP3A4 inducers (e.g., carbamazepine) may reduce lacosamide efficacy.
  • Other sodium‑channel blockers may potentiate CNS effects.

Moderate Interactions (Monitor Closely)

  • Moderate CYP3A4 inhibitors (e.g., erythromycin) may modestly raise concentrations.
  • Alcohol: may enhance sedation and dizziness.
  • Certain antiepileptics (e.g., phenobarbital) may alter plasma levels.

Frequently Asked Questions

Lacosamid Viatris is a prescription medication containing lacosamide, indicated as adjunctive therapy for partial‑onset (focal) seizures in patients with epilepsy. It helps reduce seizure frequency when added to an existing antiepileptic regimen.

Lacosamide enhances the slow inactivation of voltage‑gated sodium channels in neuronal membranes, stabilizing hyper‑excitable neurons and decreasing repetitive firing that leads to seizures.

The specific dose and titration schedule are determined by the prescribing clinician based on individual patient factors such as age, renal function, and concomitant medications. The prescriber sets the appropriate regimen.

Safety data for lacosamide during pregnancy and lactation are limited; the drug is classified with an unknown pregnancy category. Use only if the potential benefit outweighs the risk, and discuss with a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any required import documentation.

Compared with other sodium‑channel blockers such as carbamazepine or oxcarbazepine, lacosamide selectively enhances slow inactivation, which may result in a different side‑effect profile and lower risk of certain drug‑drug interactions. Clinical choice depends on efficacy, tolerability, and patient‑specific factors.

Lacosamid Viatris should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect from moisture and light. Keep the product out of reach of children and do not use after the expiry date.

The product is taken orally, usually as a tablet or oral solution, and should be swallowed with water. It may be taken with or without food, but patients should follow the prescribing clinician’s instructions regarding timing and any required dose adjustments.

Serious adverse reactions include cardiac conduction abnormalities such as PR‑interval prolongation, severe skin reactions, hypersensitivity, and suicidal thoughts. Patients should seek immediate medical attention if they experience palpitations, rash, or mood changes.

Lacosamide is contraindicated in patients with known hypersensitivity to the drug or any of its excipients. Caution is advised for individuals with significant cardiac conduction disorders, severe renal impairment, or those taking other sodium‑channel‑blocking agents, unless a clinician determines the benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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