Product image of Lacosamida Cinfa (Lacosamide) supplied by GNH India

Lacosamida Cinfa

Active Ingredient:
Lacosamide
Origin:
EU

Lacosamida Cinfa (Lacosamide)

Lacosamide, the active ingredient in Lacosamida Cinfa, is an anticonvulsant presented as an oral tablet for oral use. It treats partial‑onset seizures in patients with epilepsy.

GNH India supplies Lacosamida Cinfa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratorios Cinfa S.A.

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Indications & Clinical Uses

  • Lacosamide is an antiepileptic drug used to control seizure activity in the central nervous system.
  • Partial‑onset seizures: reduces the frequency and severity of focal seizures.
  • Epilepsy: provides adjunctive therapy for patients with refractory epilepsy.
  • Adjunctive therapy: used alongside other antiepileptic medications to improve overall seizure control.

How It Works

  • Lacosamide enhances the slow inactivation of voltage‑gated sodium channels in neuronal membranes, stabilizing hyperexcitable neuronal membranes and limiting repetitive firing. This modulation reduces the propagation of epileptiform activity without significantly affecting normal neuronal function.

Side Effects

Lacosamide may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Dizziness
  • Headache
  • Nausea
  • Fatigue
  • Diplopia (double vision)
  • Somnolence

Serious or Rare Side Effects

  • Suicidal thoughts or behavior
  • Severe skin reactions (e.g., Stevens‑Johnson syndrome)
  • Cardiac arrhythmias or PR‑interval prolongation
  • Hypersensitivity reactions (anaphylaxis)
  • Liver enzyme elevations
  • Severe respiratory depression (rare).

Precautions & Warnings

  • When prescribing Lacosamide, consider the following precautions.
  • Renal impairment: adjust dose in patients with reduced kidney function.
  • Hepatic impairment: monitor liver function and consider dose adjustment.
  • Cardiac conduction disorders: avoid in patients with known PR‑interval prolongation.
  • Pregnancy: safety not established; weigh benefits against potential risks.
  • Driving and operating machinery: caution due to possible dizziness or somnolence.
  • Store at ambient temperature below 25°C: keep in the original container, protect from moisture.

Avoid Interactions

Lacosamide can interact with several medications; awareness of interaction severity is essential.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., carbamazepine, phenytoin, phenobarbital) may markedly reduce lacosamide plasma levels.
  • Concurrent use with other sodium‑channel blockers (e.g., lamotrigine) can increase risk of cardiac conduction abnormalities.
  • QT‑prolonging agents may exacerbate cardiac rhythm effects.

Moderate Interactions (Monitor Closely)

  • Hormonal contraceptives: efficacy may be decreased, requiring additional contraceptive measures.
  • Alcohol: may enhance central nervous system depression.
  • Other antiepileptic drugs: monitor for additive side‑effects such as dizziness or fatigue.

Frequently Asked Questions

Lacosamida Cinfa contains lacosamide, an antiepileptic medication indicated for the treatment of partial‑onset seizures in patients with epilepsy, either as monotherapy or as adjunctive therapy.

Lacosamide enhances the slow inactivation of voltage‑gated sodium channels in neurons, stabilizing hyper‑excitable membranes and reducing the repetitive firing that leads to seizure activity.

The dosage of lacosamide is individualized by the prescribing clinician based on the patient’s clinical condition, response, and tolerability. Specific dosing regimens should be obtained from a qualified healthcare professional.

Safety of lacosamide in pregnancy and lactation has not been fully established. Clinicians must weigh potential benefits against possible risks and consider alternative therapies when appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Lacosamide’s unique mechanism—enhancing slow sodium‑channel inactivation—differs from many traditional antiepileptics that target fast inactivation. This can offer an alternative for patients who have inadequate seizure control with other agents, though individual response varies.

Store the product at ambient temperature below 25 °C, in its original packaging, and protect it from moisture. Do not expose the tablets to excessive heat or humidity to maintain potency.

Lacosamida Cinfa is administered orally, typically as a tablet taken with or without food. The exact administration schedule should follow the prescriber’s instructions.

Serious risks include the potential for suicidal thoughts or behavior, severe skin reactions such as Stevens‑Johnson syndrome, and cardiac conduction abnormalities like PR‑interval prolongation. Patients should be monitored closely for these events.

Lacosamide should be avoided in patients with known hypersensitivity to the drug, significant cardiac conduction disorders, or those taking strong CYP3A4 inducers without appropriate dose adjustments. Clinicians should assess each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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