Product image of Lacosamida Eugia (Lacosamide) supplied by GNH India

Lacosamida Eugia

Active Ingredient:
Lacosamide
Origin:
EU

Lacosamida Eugia (Lacosamide)

Lacosamide, the active ingredient in Lacosamida Eugia, is an anticonvulsant presented as an intravenous formulation for injection use. Classified under ATC code N03AX13, it is employed in the management of partial‑onset seizures in adult patients, reducing neuronal hyperexcitability through modulation of sodium channels and is marketed within the European Union. It is supplied only by prescription.
GNH India supplies Lacosamida Eugia as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory support for cross‑border distribution.

Manufacturer / TM Owner

Eugia Pharma (Malta) Ltd

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Indications & Clinical Uses

  • Lacosamide is an anticonvulsant used in the management of seizure disorders.
  • Partial‑onset seizures: reduces seizure frequency in adults with focal epilepsy.
  • Adjunct therapy for focal seizures: added when monotherapy does not achieve adequate control.

How It Works

  • Lacosamide enhances the slow inactivation of voltage‑gated sodium channels in neuronal membranes, stabilizing hyperexcitable neuronal membranes and thereby decreasing the likelihood of repetitive firing that underlies seizure activity.

Side Effects

Common Side Effects

  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Headache: mild to moderate pain in the head region.
  • Nausea: feeling of queasiness often without vomiting.
  • Fatigue: unusual tiredness or lack of energy.
  • Blurred vision: temporary visual disturbances.
  • Somnolence: increased sleepiness or drowsiness.

Serious or Rare Side Effects

  • Cardiac conduction abnormalities: PR‑interval prolongation that may lead to arrhythmia.
  • Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Suicidal ideation: emergence of thoughts of self‑harm.
  • Hepatic dysfunction: abnormal liver enzyme elevations.
  • Respiratory depression: reduced breathing effort, especially with CNS depressants.
  • Hypersensitivity reactions: including anaphylaxis or severe allergic response.

Precautions & Warnings

  • Precautions should be observed when prescribing lacosamide.
  • Renal impairment: monitor renal function and adjust therapy as needed.
  • Hepatic impairment: use caution and assess liver enzymes regularly.
  • Cardiac conduction abnormalities: avoid in patients with known PR‑interval prolongation.
  • Pregnancy: risk unknown; prescribe only if benefit outweighs potential risk.
  • Concomitant CNS depressants: monitor for additive sedation.
  • Store at below 25°C: keep in the original container, protect from light and moisture.

Avoid Interactions

Lacosamide may interact with several medications.

Major Interactions (Avoid)

  • Carbamazepine: induces metabolism, lowering lacosamide levels.
  • Phenytoin: induces metabolism, reducing efficacy.
  • Strong CYP2C19 inhibitors (e.g., fluconazole): increase lacosamide exposure.

Moderate Interactions (Monitor Closely)

  • CNS depressants (benzodiazepines, opioids): may enhance sedation.
  • Alcohol: can increase dizziness and drowsiness.
  • Diuretics: monitor electrolytes and renal function.

Frequently Asked Questions

Lacosamida Eugia contains lacosamide, an anticonvulsant indicated for the treatment of partial‑onset (focal) seizures in adult patients with epilepsy. It is used to reduce the frequency of seizures when prescribed by a qualified healthcare professional.

Lacosamide enhances the slow inactivation of voltage‑gated sodium channels in neuronal membranes. This stabilizes hyperexcitable neurons and diminishes repetitive firing, which helps to control seizure activity in the brain.

The specific dose and dosing schedule are determined by the prescribing clinician based on the patient’s medical condition, response, and other individual factors. Lacosamide dosing should always follow the prescriber’s instructions.

Safety data for lacosamide in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the possible risk to the fetus or infant, and the decision must be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lacosamide has a distinct mechanism that enhances slow sodium‑channel inactivation, differing from many older antiepileptics that act on fast inactivation. This can provide an alternative for patients who have inadequate response or intolerable side effects with other agents.

Lacosamida Eugia should be stored at temperatures below 25 °C, in its original packaging, protected from light and moisture. Follow standard aseptic handling procedures for intravenous products.

The product is supplied as an intravenous solution and is administered by a healthcare professional via infusion or injection, according to the prescribing information and institutional protocols.

Serious risks include cardiac conduction abnormalities such as PR‑interval prolongation, severe skin reactions like Stevens‑Johnson syndrome, suicidal thoughts, and rare cases of hepatic dysfunction. Patients should be monitored for these events during therapy.

Lacosamida Eugia is contraindicated in patients with known hypersensitivity to lacosamide or any of the formulation components, and it should be used with caution in individuals with significant cardiac conduction disorders, severe renal or hepatic impairment, or those taking interacting medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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