Product image of Lacosamida Farmoz (Lacosamide) supplied by GNH India

Lacosamida Farmoz

Active Ingredient:
Lacosamide
Origin:
EU

Lacosamida Farmoz (Lacosamide)

Lacosamide, the active ingredient in Lacosamida Farmoz, is an anticonvulsant presented as an oral tablet for oral use. It works by stabilizing neuronal membranes and is indicated for the treatment of partial‑onset seizures in patients with epilepsy, including those who have not responded adequately to other therapies.

GNH India supplies Lacosamida Farmoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across markets.

Manufacturer / TM Owner

Farmoz - Sociedade Técnico Medicinal, S.A.

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Indications & Clinical Uses

Lacosamide is an anticonvulsant that targets focal seizure activity.

  • Partial‑onset seizures: reduces seizure frequency as monotherapy or adjunct therapy.
  • Focal epilepsy: provides seizure control in patients with focal onset seizures.
  • Adjunctive therapy for refractory focal seizures: used when other antiepileptic drugs are insufficient.

How It Works

  • Lacosamide enhances the slow inactivation of voltage‑gated sodium channels, stabilizing hyper‑excitable neuronal membranes, and modulates collapsin response mediator protein‑2 (CRMP‑2) activity, which together diminish neuronal firing and reduce seizure propagation.

Side Effects

Lacosamide may cause a range of adverse reactions.

Common Side Effects

  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Headache: mild to moderate pain in the head region.
  • Nausea: feeling of queasiness, sometimes with vomiting.
  • Fatigue: unusual tiredness or lack of energy.
  • Blurred vision: temporary visual disturbances.
  • Somnolence: increased sleepiness during the day.

Serious or Rare Side Effects

  • Cardiac conduction abnormalities: PR interval prolongation or arrhythmia.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Suicidal ideation: emergence of thoughts of self‑harm.
  • Hypersensitivity reactions: rash, angioedema, or anaphylaxis.
  • Liver enzyme elevations: abnormal hepatic function tests.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Pregnancy: risk unknown; use only if potential benefit justifies the risk.
  • Renal function: monitor patients with impaired renal clearance.
  • Cardiac conduction: obtain baseline ECG in patients with known heart disease.
  • Concomitant CNS depressants: use with caution to avoid excessive sedation.
  • Alcohol: avoid excessive consumption as it may enhance CNS effects.
  • Store at ambient temperature: keep below 25°C, retain in original packaging, and protect from moisture.

Avoid Interactions

Lacosamide can interact with several medicines; review patient medication lists.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., carbamazepine, phenytoin): may markedly reduce lacosamide plasma levels.
  • Drugs that prolong PR interval (e.g., class I antiarrhythmics): increase risk of cardiac conduction delays.
  • Other sodium‑channel blockers (e.g., oxcarbazepine): may heighten central nervous system adverse effects.

Moderate Interactions (Monitor Closely)

  • Antidepressants such as bupropion: can raise lacosamide exposure.
  • Warfarin: monitor INR as lacosamide may affect anticoagulation control.
  • Alcohol: may potentiate sedation and dizziness.

Frequently Asked Questions

Lacosamida Farmoz contains lacosamide, an anticonvulsant indicated for the treatment of partial‑onset seizures in patients with epilepsy. It may be prescribed as monotherapy or as an add‑on therapy when seizure control is not achieved with other antiepileptic drugs.

Lacosamide enhances the slow inactivation of voltage‑gated sodium channels, which stabilizes hyper‑excitable neuronal membranes. It also modulates CRMP‑2 activity, a protein involved in neuronal signaling, thereby reducing abnormal neuronal firing that leads to seizures.

The dosing regimen for Lacosamida Farmoz is individualized. A qualified prescriber determines the appropriate dose based on the patient’s clinical condition, response to therapy, and any relevant laboratory parameters.

The safety of lacosamide in pregnancy and lactation has not been definitively established. It should be used only if the potential therapeutic benefit justifies the potential risk to the fetus or infant, and under close medical supervision.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lacosamide’s unique mechanism—enhancing slow sodium‑channel inactivation—differs from many traditional antiepileptics that target fast inactivation. This can provide complementary seizure control when combined with other agents, and it is generally well tolerated, though individual response varies.

Lacosamida Farmoz should be stored at ambient temperature, below 25 °C, in its original packaging to protect from moisture. Keep the product out of direct sunlight and away from excessive heat or humidity.

The medication is taken orally, usually as a tablet, with or without food as directed by the prescribing clinician. Swallow the tablet whole with water and follow the dosing schedule provided by the healthcare professional.

Serious adverse events include cardiac conduction abnormalities such as PR‑interval prolongation, severe skin reactions like Stevens‑Johnson syndrome, and emergence of suicidal thoughts. Patients should be monitored for these signs, and any concerning symptoms should prompt immediate medical evaluation.

Lacosamida Farmoz is contraindicated in patients with known hypersensitivity to lacosamide or any of its excipients. Caution is also advised for individuals with significant cardiac conduction disorders, severe hepatic impairment, or those taking medications that may cause dangerous drug interactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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