Product image of Lacosamida Stada (Lacosamide) supplied by GNH India

Lacosamida Stada

Active Ingredient:
Lacosamide
Origin:
EU

Lacosamida Stada (Lacosamide)

Lacosamide, the active ingredient in Lacosamida Stada, is an anticonvulsant presented as an oral tablet for oral use. It is employed in the treatment of partial‑onset seizures and as adjunctive therapy in epilepsy, helping to stabilize neuronal activity in patients with refractory seizures.

GNH India supplies Lacosamida Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable sourcing for regulated markets through a robust distribution network.

Manufacturer / TM Owner

Laboratorio Stada, S.L.

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Indications & Clinical Uses

  • Lacosamide is an anticonvulsant indicated for seizure disorders.
  • Partial‑onset seizures: used as adjunctive therapy to reduce seizure frequency.
  • Focal epilepsy: improves overall seizure control when combined with other antiepileptic drugs.
  • Adjunctive therapy in epilepsy: contributes to seizure management in patients not controlled by monotherapy.

How It Works

  • Lacosamide enhances the slow inactivation of voltage‑gated sodium channels, which reduces neuronal hyperexcitability. By stabilizing the neuronal membrane, it limits the repetitive firing of neurons that underlies seizure activity, thereby providing antiepileptic effects without markedly affecting normal neuronal conduction.

Side Effects

Lacosamide may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Dizziness
  • Headache
  • Nausea
  • Fatigue
  • Blurred vision
  • Diplopia

Serious or Rare Side Effects

  • Cardiac conduction abnormalities (e.g., PR‑interval prolongation)
  • Suicidal thoughts or behavior
  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Hypersensitivity reactions including anaphylaxis
  • Hepatic enzyme elevations

Precautions & Warnings

  • Before initiating therapy, clinicians should evaluate patient‑specific factors and monitor for potential risks.
  • Renal function: assess before initiating therapy.
  • Hepatic function: monitor liver enzymes during treatment.
  • Cardiac conduction: ECG monitoring for PR‑interval prolongation.
  • Concomitant CNS depressants: use with caution.
  • Pregnancy and lactation: risk unknown; weigh benefits versus risks.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Lacosamide can interact with several medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., carbamazepine, phenytoin): may reduce lacosamide levels.
  • Class III antiarrhythmics (e.g., amiodarone): may increase lacosamide exposure.
  • Other sodium‑channel blockers (e.g., lamotrigine): may increase central nervous system adverse effects.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: may have reduced efficacy.
  • Serotonergic agents: monitor for serotonin syndrome.
  • Alcohol: may enhance dizziness and sedation.

Frequently Asked Questions

Lacosamida Stada contains lacosamide, an anticonvulsant indicated for the adjunctive treatment of partial‑onset seizures and for broader epilepsy management when additional seizure control is needed alongside other antiepileptic drugs.

Lacosamide enhances the slow inactivation of voltage‑gated sodium channels, which stabilizes hyperexcitable neuronal membranes and reduces the repetitive firing of neurons that can trigger seizure activity.

The appropriate dose is individualized by the prescribing clinician based on factors such as the patient’s age, weight, renal and hepatic function, seizure type, and response to therapy. No fixed regimen is provided here.

The pregnancy category for lacosamide is not definitively established. Use during pregnancy or lactation should only occur when the potential benefit justifies any potential risk to the fetus or infant, and under close medical supervision.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Lacosamide’s unique mechanism—enhancing slow sodium‑channel inactivation—differs from many agents that block fast inactivation. This can offer complementary seizure control when combined with other antiepileptics, and it may have a distinct side‑effect profile compared with drugs such as carbamazepine or levetiracetam.

Store the product at ambient temperature, preferably below 25 °C. Keep it in the original packaging, protect it from moisture, heat and direct light, and ensure the container is tightly closed to maintain stability.

Lacosamida Stada is taken orally, usually as a tablet. It should be swallowed whole with water and can be taken with or without food, following the dosing schedule prescribed by the treating physician.

Serious risks include cardiac conduction abnormalities such as PR‑interval prolongation, the potential for suicidal thoughts or behavior, severe skin reactions like Stevens‑Johnson syndrome, hypersensitivity reactions, and significant liver enzyme elevations.

Patients with known hypersensitivity to lacosamide or any excipients, those with severe cardiac conduction disorders, and individuals for whom the prescriber determines the risk outweighs the benefit should avoid using this medication.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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